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Ronald D. Graff, PhD

Research Assistant Professor
     
5129 Thurston Building
CB #7280
UNC School of Medicine
Chapel Hill, NC 27599-7280
919.966.0573
 E-mail: rgraff@med.unc.edu
Education:
  • BS: University of Waterloo, Ontario, Canada
  • PhD (combined program in toxicology): Rutgers, The State University of New Jersey, and University of Medicine and Dentistry of New Jersey
Honors, Awards, and Recognitions:
  • Independent Investigator Award, Arthritis Foundation
  • National Research Service Award
Research Interests:
Our lab studies cartilage biology and osteoarthritis with chondron cultures. A chondron is a chondrocyte with its surrounding pericellular matrix. Chondrons were first isolated from articular cartilage by Tony Poole using homogenization (mechanically isolated chondrons) see references below. In our lab, chondrons are isolated using the enzymes, dispase and collagenase (enzymatically isolated) see references below. Chondrons produce more extracellular matrix than chondrocytes isolated without their pericellular matrix.
Academic Appointments:
1992-1995 Research Assistant; Neurotoxicology Laboratories, School of Pharmacy, Rutgers University
1995-1998 Postdoctoral Fellow; Department of Biochemistry, UNC School of Medicine
1998-2003 Postdoctoral Fellow; Thurston Arthritis Research Center (TARC), UNC School of Medicine
2003-present Research Assistant Professor; TARC and Department of Orthopaedics (joint appointment), UNC School of Medicine
Selected Publications:
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Revised June 2006