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Journal Covers and highlighted articles by Pharmacology faculty.
Click on images for larger views. |
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Harden and Sondek Labs - Cover of Molecular Cell
"General and versatile autoinhibition of phospholipase C isozymes. " Abstract |
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David Siderovski and Francis Willard are Guest Editors for a two-issue set of papers in the journal Combinatorial Chemistry and High Throughput Screening describing "new technologies and new opportunities for screening compound libraries for modulators of GPCR signaling."
Their editorial introduction to the June 2008 issue can be read here. |
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Samulski Lab - Cover of Virology
"Surface loop dynamics in adeno-associated virus capsid assembly." Abstract |
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Zhang Lab - Cover of Cancer Cell
"Targeted inactivation of Mdm2 E3 ubiquitin ligase activity in the mouse reveals novel mechanistic insights into p53 regulation." Abstract |
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Samulski Lab - Cover of Virology
"Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions." Abstract |
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Richard Mailman - Cover of Trends in Pharmacological Sciences
"GPCR functional selectivity has therapeutic impact" Abstract |
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McCarthy Lab - Neuron publication
"Selective Stimulation of Astrocyte Calcium In Situ Does Not Affect Neuronal Excitatory Synaptic Activity" Abstract |
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Gary Johnson is Guest Editor for the May 14, 2007 issue of Oncogene, along with DN Dhanasekaran. Oncogene issue
Their introduction to the issue is titled "MAPKs: function, regulation, role in cancer and therapeutic targeting." Article
Figure 1: "Integration of the MAPK pathway in the cellular response to environmental stimuli." Artwork by Betsy Clarke. |
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Siderovski Lab - Research on G-alpha proteins is highlighted in the Spring 2007 edition of Endeavors, UNC's Research and Creative Activity Magazine.
"Picture Perfect Proteins" by Molly Davis Article
Before and After Photo of protein-crystallization image stablized by the addition of a peptide, making the image crystal clear. |
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Wang Lab - Cover of Molecular Cell
"General and specific functions of exonic splicing silencers in splicing control."Abstract |
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Johnson Lab - Cover of Journal of Biological Chemistry
"MEKK4 is an effector of the embryonic TRAF4 for JNK activation." Abstract |
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Parise Lab - Research on sickle cell adhesion is highlighted in the Spring 2006 edition of Endeavors, UNC's Research and Creative Activity Magazine.
"Getting Past Stickiness" by Jan McColm Article
Photo of Leslie Parise, Julie Brittain and Sheritha Lee. |
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Hahn Lab - Cover of Cytometry
"Functional Proteometrics for Cell Migration" Abstract |
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Cox Lab - Cover of Molecular Cell
"PKC Regulates a Farnesyl-Electrostatic Switch on K-Ras that Promotes its Association with Bcl-XL on Mitochondria and Induces Apoptosis" Abstract |
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Hahn Lab - Nature publication
"Spatiotemporal dynamics of RhoA activity in migrating cells" Abstract |
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Nicholas Lab - Selected as the highlight paper in Journal of Bacteriology
"Porin-Mediated Antibiotic Resistance in Neisseria gonorrhoeae: Ion, Solute, and Antibiotic Permeation through PIB Proteins with penB Mutations" Abstract |
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Parise Lab - Cover of the Journal of Cell Biology
"Essential role of CIB1 in regulating PAK1 activation and cell migration" Abstract |
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Sondek Lab - Cover of Structure
"Crystal structures of the type III effector protein AvrPphF and its chaperone reveal residues required for plant pathogenesis" Abstract |
