The
Marion I. Barnhart Memorial LectureOur dear friend and colleague, Marion Barnhart, had a brilliant career in medical and scientific research and education. Her many important discoveries in the fields of cellular physiology, blood coagulation and thrombosis, platelet vessel wall interactions and other aspects of hematology won her national and international acclaim and numerous awards and will have
a lasting impact on scientific thinking. Although she was 64 when she died, the Dean of Wayne State University's medical school noted that she was undoubtedly the youngest member of the faculty in terms of enthusiasm, excitement, energy, productivity, and her always upbeat, positive attitude.
Marion received the PhD degree in cellular physiology from the University of Missouri in 1950 and then came to Detroit as an instructor in physiology and pharmacology at Wayne State University School of Medicine. She was the first recipient of the Distinguished Graduate Faculty Award given at Wayne State University in 1974. Among her contributions are the description of the cellular sites for synthesis of prothrombin, fibrinogen and other blood coagulation proteins, the demonstration of the important role played by neutrophils and eosinophils in fibrin dissolution, scanning electron microscopy of the sequence of events in platelet activation and platelet-vessel wall interactions, circulatory pathways in the human spleen and the development of the human umbilical vein model for studying platelet-vessel wall interactions.
When she met her untimely death, Marion was the Director of the Bargman Laboratory for Cell and Molecular Research, was the Principal Investigator/Director of an NIH multidisciplinary training grant in Experimental Hematology, and Professor of Physiology at Wayne State University. In addition, she was chairperson of the Hemostasis Committee of the NIH's Blood Diseases and Resources Advisory committee, and a Charter member of Wayne State's Academy of Scholars. With her vibrant personality, great enthusiasm and genuine warmth, Marion touched and enriched the lives of all who were fortunate enough to interact with her. She believed in striving for excellence in whatever one did and served as a superb role model for all--not only as a scientist and educator, but a wonderful, caring human being.
Marion Barnhart Memorial Lecturers
| 1987 J. Evan Sadler 1989 Marjorie B. Zucker 1991 Kai Simons 1993 Robert Rosenberg |
1995 Peter Carmeliet 1997 V. Fuster 1999 D. Collen 2001 Edward F. Plow |
2003 Peter Carmeliet 2005 Denisa Wagner 2007 John F. Hartwig |
The Kenneth M. Brinkhous Memorial Lecture
Kenneth M. Brinkhous was an influential leader and charter member of the ISTH. He was one of the 16 original members of a committee organized in 1954 as the International Committee for the Standardization of the Nomenclature of the Blood Clotting Factors. This committee expanded in 1969 into the ISTH with 173 members. Dr. Brinkhous was elected as one of the founding board members of the Society and he served as the Secretary General for 12 years. His leadership of the ISTH and the SSC is recognized by this lectureship which has been endowed by a generous contribution of Wyeth.
Kenneth M. Brinkhous Memorial Lecturers
2007 Ian R. Peake
Robert P. Grant was a renowned cardiologist with interdisciplinary research interests. He was born in 1915 in Ontario and received his MD from Cornell Medical College in 1940. He interned at the Peter Bent Brigham and New York Hospitals. Dr. Grant was a Visiting Physician at Emory Grady Hospital in Atlanta, Georgia (USA). He joined the National Heart Institute European Director stationed in Paris and worked in many way to facilitate international research and communications. He was recalled to Bethesda in March, 1996, to become the National Heart Institute Director and established a research grant for the study of thrombosis and hemorrhagic diseases. He died in August, 1966.
Dr. Grant was a distinguished cardiologist and student of cardiovascular physiology. He was for many years a member of the intramural staff of the National Heart Institute. Having a great interest in the development of young scientists and clinicians, he became Chief of Training Grants and Fellowships in the Institute's intramural programs, a position which brought him into contact with every academic cardiology department in America. He became a trusted counselor in the establishment of research and training programs at many institutions. He later spent five years as representative of the National Institutes of Health in Europe. With headquarters at the American Embassy in Paris, he traveled extensively, facilitating American-European collaboration in medical research and education. He was called home to be Director of the National Heart Institute in March of 1966. Thus, he had a very wide association nationally and internationally, and his sudden death in August 1966 was a grievous shock to many devoted friends. Contributions to a memorial fund came from many donors. Trustees of the fund deliberated at length to find a suitable memorial and finally decided in 1969 to award the fund to the newly formed International Society on Thrombosis and Haemostasis for creation of a medal to be used in honoring individuals who make outstanding contributions to progress. The international scope and the scientific content of the Society's programs were eminently suitable for the Robert P. Grant memorial.
The Robert P. Grant Medal is the highest award of the ISTH. It is presented at each biennial Congress of the Society to a recipient selected for outstanding service or accomplishment which has promoted the goals of the Society. This award may be for research achievement, for organizational activities, for important public recognition and support of research activities, for facilitation of institutional cooperation and communications, for unusual teaching or educational initiatives, or for the development of concepts which result in a clearer understanding of the meaning of research data.
Robert P. Grant Medal Recipients
| 1975 R.G. Macfarlane 1977 Sol Sherry 1979 Jacques Caen 1980 Oscar Ratnoff 1983 Ernst Luscher 1985 Kenneth M. Brinkhous |
1987 J. Fraser Mustard 1989 Earl W. Davie 1991 Samuel I. Rapaport 1993 Marc Verstraete 1995 Harold R. Roberts 1997 Kenneth G. Mann |
1999 Jan J. Sixma 2001 Pier M. Mannucci 2003 Yale Nemerson 2005 Dominique Meyer 2007 Uri Seligsohn |
The
Shirley Johnson Memorial Lecture
Shirley Alma Johnson was born April 15, 1922 in Mervin, Saskatchewan, Canada, and died September 11, 1970 in Washington, DC. She received her PhD in Physiology from the University of Toronto in 1949. Her first position was teaching physiology at the College of Osteopathy and Surgery, Kirksville, MO. Her outstanding career in the field of coagulation was launched between 1951 and 1956 as a research associate and later as friend and colleague of Professor Walter H. Seegers in the Department of Physiology and Pharmacology at Wayne State University, Detroit, Michigan. Her early interests encompassed the plasma coagulation factors, but became focused on the ultrastructure and pathophysiology of platelets. Her later publications dealt mainly with the interaction of platelets with the fibrin clotting mechanisms and the vascular endothelium. The careful, systematic research establishing the endothelial supporting function of platelets could serve as a model for any investigators in the field of hemostasis and thrombosis.
Dr. Johnson headed the Divisions of Coagulation at the Henry Ford Hospital, Detroit (1956-1960); the Milwaukee County General Hospital (1960-1963); Wood Veterans Administration Medical Center, Milwaukee, Wisconsin (1963-1966); and the Veterans Administration Medical Center, Washington, DC (1967-1970) with faculty appointments at Wayne State University, Marquette University College of Medicine, Georgetown and George Washington Colleges of Medicine, respectively. She was a very active member in the ISTH and the early ICTH.
Her 96 scientific publications and the five books she co-authors and co-edited remain as monuments to the industry, talent and effective life-style of a dedicated and talented scientist.
This lectureship is dedicated to a great lady who inspired excellence in her students and associates. She loved people, literature, music and travel. She was beloved in the international scientific community and will ever be remembered by all who knew her.
The Shirley A. Johnson Memorial Lecturers
| 1972 Walter H. Seegers 1973 J. Fraser Mustard 1975 G.V.R. Born 1977 Bengt Samuelsson 1979 John R. Vane 1981 Ernst Luscher 1983 Johan Stenflo |
1985 Inga Marie Nilsson 1987 Ralph L. Nachman 1989 -the late Theodore S. Zimmerman (by Z.M. Ruggeri) 1991 Edward F. Plow 1993 Harold R. Roberts 1995 Barry Coller |
1997 Graham Jamieson 1999 Robert D. Rosenberg (Yale Nemerson, lecturer) 2001 Robert D. Rosenberg 2003 Bonno N. Bouma 2005 David Phillips 2007 Johannes Oldenburg |
The
Wright-Schulte Memorial Lecture
In 1976 a gift to the Society established the Wright-Schulte Lecture. The Lecture commerates Mr. Arthur Schulte (at right, a successful merchant and philanthropist who was the first American patient to receive heparin therapy and his physician, Irving S. Wright, MD (at left).
Dr. Wright's contributions to the filed of thrombosis and hemostasis are legendary. He was the driving force in the establishment and success of the International Committee on the Nomenclature of the Blood Clotting Factors (now known as the Scientific and Standardization Committee of the ISTH) and served as it's Chairman during its formative years (1954-1963). He spearheaded and directed the first major trial sponsored by the American Heart Association on oral anticoagulation in acute myocardial infarction. He was the dominant figure from the mid-1940s to the mid-1960s in drawing attention in the United States and beyond to the importance of the thrombosis problem and the need to foster and expand research on this subject.
As a result of his motivating influence and organizational abilities, the International Society on Thrombosis and Haemostasis was founded in 1969.
The Wright-Schulte Memorial Lecturers
| 1975 Helge Stormorken 1977 V.V. Kakkar 1979 Oscar Ratnoff 1981 Marc Verstraete |
1983 Bjarne Østerud 1985 Nubuo N. Aoki 1987 H. Coen Hemker 1989 Yale Nemerson |
2001 Robin W. Carrell 2003 P. M. Mannucci 2005 David Ginsburg 2007 Richard O. Hynes |
The
Pia Glas-Greenwalt Memorial Lecture
Pia Glas was born in 1932, in Sigmaringen, Germany, and studied medicine at the Eberhard-Karl University Medical School in Tubingen. The direction of her career was evident in her Doctoral thesis, which was entitled "Fibrinolgenolysis following plasminogen activation by streptokinase." She continued postdoctoral training with Dr. Tage Astrup to Washington, DC, at the James F. Mitchell Foundation. She returned briefly to Tubingen for further training in medicine and certification in hematology, but came back to the Mitchell Foundation in 1970. It was there that she married Tibby Greenwalt. When Dr. Astrup retired, Dr. Glas-Greenwalt was promptly recruited to be the civilian Head of the Coagulation Division, Department of Experimental Pathology, at the Naval Research Institute in Bethesda, MD.
Dr. Glas-Greenwalt moved to the University of Cincinnati in 1979, where she continued her research in fibrinolysis. In the early 1980's, she was a pioneer in the field of plasma proteins being used as inhibitors for t-PA and urokinase. She identified increased plasma levels of what proved to be plasminogen activator inhibitor-1 in patients with systemic lupus erythematosus.
In 1990, Dr. Glas-Greenwalt moved to the Good Samaritan Hospital to create and direct a state-of-the-art Fibrinolysis/Special Coagulation laboratory. She had long investigated the properties and therapeutic uses of the defibrinating enzyme Ancrod, and at the time of her death in 1996, she was engaged in laboratory analyses for 600 patients, in a study of Ancrod as therapy for ischemic stroke.
The Pia Glas-Greenwalt Memorial Lecturers
| 1999 David J. Loskutoff 2001 George J. Broze |
2003 J. Ironside 2005 Douglas Vaughan |
2007 John H. Griffin |
The Harold R. Roberts Award for Distinguished Service to the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis
Since the founding in 1954 of the International Committee for the Standardization of the Nomenclature of the Blood Clotting Factors, many distinguished individuals have unselfishly offered their time and talents in support of the mission of the Committee.
None served longer or with more distinction than Dr. Harold R. Roberts. Dr. Roberts first became active in the work of the Committee in 1966 and was a charter member of the International Society on Thrombosis and Haemostasis when it was organized in 1970. He served as Secretary General of the Committee from 1978 to 1988 when the Committee merged administratively with the ISTH. He then took the reins of both the Committee and Society as its first Executive Director and led the organization for another eleven years. For more than 20 years, he has been a leader, a mentor, a counselor and scientific diplomat internationally recognized for his fairness, wisdom and unselfish devotion to the Committee and the Society.
The Committee and the Society wish to acknowledge the work and to honor the legacy of Harold Roberts' service through creation of a permanent award. In keeping with the legacy of Dr. Roberts, the award honors meritorious service to the SSC, beyond expectations and over a significant period of time.
The inaugural Harold R. Roberts award will be given in conjunction with the 52 nd SSC Annual Meeting in Oslo. Presentation of the Harold R. Roberts Award will be made during the Welcoming Reception at Oslo City Hall on Thursday evening, 29 June, 2006.
The Harold R. Roberts Medal Recipients
2006 Jane G. Lenahan
2007 Margareta Blombäck
Sol Sherry (1916-1993) was a founder of the International Society on Thrombosis and Haemostasis and leader of the Society for 6 years as its first Chairman. His scientific career spanned 70 years and his contributions to scientific research on thrombosis and thrombolysis and subsequent clinical application has earned him the title, "Father" of thrombolytic therapy.
Dr. Sherry's early research was in the laboratory of Dr. Elaine Ralli on the physiology and metabolism of Vitamin C. Following distinguished service in WWII as a flight surgeon and head of the US Army's Eastern European Typhus Control mission, he returned to research with Dr. W.S. Tillet who was investigating the therapeutic potential of streptococcal enzymes. As Director of the May Institute of Medical Research at the University of Cincinnati, Dr. Sherry and colleagues studied clotting and fibrinolytic enzyme systems. As Director of Medicine at Jewish Hospital in St. Louis, Dr. Sherry lead research establishing the safety and efficacy of clot dissolution in thrombotic disease.
Dr. Sherry's immense achievements in the field of thrombosis and thrombolysis, particularly the introduction of streptokinase into clinical practice for the treatment of thrombotic disorders, such as deep vein thrombosis, pulmonary embolism and acute myocardial infarction have saved many lives and improved the quality of life for patients at risk for thrombotic disorders. It is for these reasons that the ISTH established a named lectureship in his honor.
The Sol Sherry Lectureship is awarded to individuals whose work in the fields of thrombosis and hemostasis has been recognized internationally as having a long-standing and significant impact in the prevention or treatment of thromboembolic or hemostatic disorders and has contributed to a deeper understanding of the biomedical principles of these diseases and disorders.
The Sol Sherry Memorial Lecturers
| 1993 C. T. Esmon 1995 Victor J. Marder and M. M. Samama 1997 Jos Vermylen |
1999 Jurgen van de Loo and Salim Yusuf 2001 Marie-Germaine Bousser 2003 Frits R. Rosendaal |
2005 Harry Buller 2007 Jay L. Degen |
ISTH
BIENNIAL AWARDS FOR CONTRIBUTIONS TO HAEMOSTASIS
The ISTH Biennial Awards for Contributions to Hemostasis (BACH) are
presented during the biennial Congress of the Society.
Initiated in 1982, the Biennial Awards for Contributions to Hemostasis recognize individuals who, in the opinion of their co-workers and peers, have made significant contributions to research and education in blood coagulation. The awards are presented in two categories: Distinguished Career Awards and Investigator Recognition Awards.
Five Society members whose accomplishments are internationally regarded as exemplary models of excellence in research and teaching receive the BACH Investigator Recognition Award and five whose career contributions have significantly advanced the scientific community's understanding of the diseases and disorders affecting hemostasis receive the BACH Distinguished Career Award.
The Nominating Committee for the Biennial Awards is comprised of the Society's Senior Advisory Council, 99 distinguished and internationally recognized experts who have previously served as elected members of the ISTH Scientific and Standardization Committee. Final election of awardees is made by the current members of the SSC.
A list of past recipients is shown below.|
Stockholm, Sweden, 1983 Distinguished Career Awards Investigator Recognition Awards |
San Diego, CA, USA, 1985 Distinguished Career Awards Investigator Recognition Awards |
Brussels, Belgium, 1987 Distinguished Career Awards Investigator Recognition Awards |
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Tokyo, Japan, 1989 Distinguished Career Awards Investigator Recognition Awards |
Amsterdam, The Netherlands, 1991 Distinguished Career Awards Investigator Recognition Awards |
New York City, NY, USA, 1993 Distinguished Career Awards Investigator Recognition Awards |
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XVth ISTH Congress Jerusalem, Israel 1995 Distinguished Career Awards Investigator Recognition Awards |
XVIth ISTH Congress Florence, Italy 1997 Distinguished Career Awards Investigator Recognition Awards |
XVIIth ISTH Congress Washington, DC, USA 1999 Distinguished Career Awards Investigator Recognition Awards |
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XVIIIth ISTH Congress Paris, France 2001 Distinguished Career Awards Investigator Recognition Awards |
Contributions to Hemostasis XIXth ISTH Congress Birmingham, England 2003 Investigator Recognition Awards Distinguished Career Awards |
12th ISTH Biennial Awards for Investigator Recognition Distinguished Career
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13th ISTH Biennial Awards for Distinguished Career Awards Investigator Recognition Award |
Sanofi-Aventis/ISTH Fellowship Awards
Sanofi-Aventis/ISTH Fellowship Awardees
1999 Mathias Riewald and Maria R. Taliani
2001 Marina Marchetti and Galit Sarig
2003
Cecilia Becattini and Anna Zetser
2005 Wendy Lim and Anat Aharon
2007 Yona Nadir and Vera Ignjatovic