Past Events

Pathology & Lab Medicine Grand Rounds, David A. Eberhard, MD, PhD, “UNCseq: Next-Generation Clinical Cancer Genomics” Mar 21, 2013 from 08:30 AM to 09:30 AM G100 Bondurant,
Gait and Balance Impairment Following TBI: Choosing the Best Tools to Guide Intervention Mar 19, 2013 from 12:15 PM to 01:00 PM Inpatient Rehabilitation Center, 7th Floor, Memorial Hospital,
“The Emerging Landscape of Antibody and Antibody-Like Therapeutics” Mar 19, 2013 from 11:00 AM to 12:00 PM G202 MBRB,
STEPHEN DEMAREST, PhD Research Advisor Lilly Biotechnology Center Eli Lilly and Company
New insights into the biochemistry and pathology of coagulation factor XI Mar 15, 2013 from 11:00 AM to 12:00 PM Pagano Conference Room, LCCC,
Dr. David Gailiani Vanderbilt University
Friday ID Conference: Infectious Disease Surveillance in the Community and Healthcare Setting Mar 15, 2013 from 08:30 AM to 09:30 AM 1131 Bioinformatics,
Emily Sickbert-Bennett, PhD, to speak at Friday ID Conference on March 15th.
Neuroscience Center Thursday Seminar Series Mar 14, 2013 from 12:30 PM to 01:30 PM 1131 Bioinformatics,
Songhai Shi, PhD, Memorial Sloan-Kettering Cancer Center
Pathology & Lab Medicine Grand Rounds,W. Kimryn Rathmell, MD, PhD “Molecular Biology of Renal Cell Carcinoma” Mar 14, 2013 from 08:30 AM to 09:30 AM G100 Bondurant,
Coping with Emotional and Behavior Changes after TBI Mar 12, 2013 from 12:15 PM to 01:00 PM Inpatient Rehabilitation Center, 7th Floor, Memorial Hospital,
“CRYSTALLOGRAPHIC SNAPSHOTS REVEAL NEW INTERMEDIATES DURING DNA SYNTHESIS” Mar 12, 2013 from 11:00 AM to 12:00 PM 1131 Bioinformatics,
SAMUEL H. WILSON, Ph.D. Laboratory of Structural Biology NIEHS-NIH
Towards a Neuroscience of Human Emotion Mar 12, 2013 from 11:00 AM to 12:00 PM 321 MacNider Hall,
Abstract Emotions are powerful organizers of perceptual, mnemonic, motivational, and physiological processes. Understanding emotions, and their basic affective and cognitive ingredients, is essential for understanding healthy and disordered brain function. However, in spite of some claims to the contrary in the popular press, there are as yet no reliable human brain markers for affective processes. Here, I introduce an analysis framework for identifying fMRI patterns specific to particular types of mental events. This framework is qualitatively different from the "brain mapping" approach because it emphasizes a) optimization of psychological ("reverse") inference using machine learning; b) quantitative assessment of the diagnostic value of brain patterns; and c) prospective use of the same diagnostic patterns across studies. Using this approach, we have identified a brain pattern that can predict the intensity of physical pain at the level of the individual person with 90-100% accuracy in some tests. This brain marker for pain is distinct from other patterns that are diagnostic of other types of affective events (e.g., observed pain, aversive images, and romantic rejection). These results suggest that it may be possible to develop fMRI-based brain markers for distinct emotional states. Such markers would provide new ways of measuring and classifying emotions, characterizing brain disorders, and testing the effects of cognitive manipulations on pain and emotion.
Chemical Exchange Sensitive MRI: Amide and Amine Protons Mar 11, 2013 from 02:00 PM to 03:00 PM Medical Research Building D Conference Room,
Abstract: Imaging the pH and chemical compositions of the brain is important for understanding brain function and may provide useful information in clinical applications of brain diseases. Chemical exchange of protons between water and biomolecules can be exploited in magnetic resonance imaging (MRI) for measuring pH and metabolite/protein concentration changes which are detected indirectly through water signal with enhanced sensitivity by applying saturation or spin-locking radiofrequency pulses. Exchangeable amide and amine protons are abundant in the brain and have been shown to be promising chemical exchange sites in preclinical studies of brain cancer and stroke. In this talk, I will present the physical principles and the quantification and optimization issues of chemical-exchange sensitive MRI and discuss the in vivo signal source of MRI techniques sensitive to the amide- and amine–water proton exchange.
Chemical Exchange Sensitive MRI: Amide and Amine Protons Mar 11, 2013 from 02:00 PM to 03:00 PM Medical Research Building D Conference Room,
Abstract: Imaging the pH and chemical compositions of the brain is important for understanding brain function and may provide useful information in clinical applications of brain diseases. Chemical exchange of protons between water and biomolecules can be exploited in magnetic resonance imaging (MRI) for measuring pH and metabolite/protein concentration changes which are detected indirectly through water signal with enhanced sensitivity by applying saturation or spin-locking radiofrequency pulses. Exchangeable amide and amine protons are abundant in the brain and have been shown to be promising chemical exchange sites in preclinical studies of brain cancer and stroke. In this talk, I will present the physical principles and the quantification and optimization issues of chemical-exchange sensitive MRI and discuss the in vivo signal source of MRI techniques sensitive to the amide- and amine–water proton exchange.
Bowles Center for Alcohol Studies Seminar Series Mar 11, 2013 from 12:30 PM to 01:30 PM Taylor Hall 124,
Friday ID Conference: HIV in the South Mar 08, 2013 from 08:30 AM to 09:30 AM 1131 Bioinformatics,
Adaora Adimora, MD, to speak at Friday ID Conference on March 8th.
Carolina Systems Genetics Seminar Series Mar 07, 2013 from 03:00 PM to 04:00 PM Pagano Conference Room, LCCC,
David Threadgill, PhD will present the talk "Modeling population exposures in mice: the case of tricholoethylene and Camp Lejeune".
Neuroscience Center Thursday Seminar Series Mar 07, 2013 from 12:30 PM to 01:30 PM 1131 Bioinformatics,
Adam Hantman, PhD, Janelia Farm
2013 BRIC/Radiology Research Day Mar 06, 2013 from 11:30 AM to 06:00 PM NC Cancer Hospital & Bondurant G100,
“PROFILING ATP BINDING IN MYCOBACTERIUM TUBERCULOSIS: Mar 05, 2013 from 11:00 AM to 12:00 PM 1131 Bioinformatics,
CHRISTOPH GRUNDNER, Ph.D. Assistant Professor Department of Global Health University Of Washington, Seattle
Medical Management of Traumatic Brain Injury Mar 04, 2013 from 12:15 PM to 01:00 PM Inpatient Rehabilitation Center, 7th Floor, Memorial Hospital,
Traumatic Brain Injury Discussion Panel Mar 02, 2013 from 01:00 PM to 03:00 PM Inpatient Rehabilitation Center, 7th Floor, Memorial Hospital,