Past Events

Pathology & Lab Medicine Grand Rounds,W. Kimryn Rathmell, MD, PhD “Molecular Biology of Renal Cell Carcinoma” Mar 14, 2013 from 08:30 AM to 09:30 AM G100 Bondurant,
Coping with Emotional and Behavior Changes after TBI Mar 12, 2013 from 12:15 PM to 01:00 PM Inpatient Rehabilitation Center, 7th Floor, Memorial Hospital,
“CRYSTALLOGRAPHIC SNAPSHOTS REVEAL NEW INTERMEDIATES DURING DNA SYNTHESIS” Mar 12, 2013 from 11:00 AM to 12:00 PM 1131 Bioinformatics,
SAMUEL H. WILSON, Ph.D. Laboratory of Structural Biology NIEHS-NIH
Towards a Neuroscience of Human Emotion Mar 12, 2013 from 11:00 AM to 12:00 PM 321 MacNider Hall,
Abstract Emotions are powerful organizers of perceptual, mnemonic, motivational, and physiological processes. Understanding emotions, and their basic affective and cognitive ingredients, is essential for understanding healthy and disordered brain function. However, in spite of some claims to the contrary in the popular press, there are as yet no reliable human brain markers for affective processes. Here, I introduce an analysis framework for identifying fMRI patterns specific to particular types of mental events. This framework is qualitatively different from the "brain mapping" approach because it emphasizes a) optimization of psychological ("reverse") inference using machine learning; b) quantitative assessment of the diagnostic value of brain patterns; and c) prospective use of the same diagnostic patterns across studies. Using this approach, we have identified a brain pattern that can predict the intensity of physical pain at the level of the individual person with 90-100% accuracy in some tests. This brain marker for pain is distinct from other patterns that are diagnostic of other types of affective events (e.g., observed pain, aversive images, and romantic rejection). These results suggest that it may be possible to develop fMRI-based brain markers for distinct emotional states. Such markers would provide new ways of measuring and classifying emotions, characterizing brain disorders, and testing the effects of cognitive manipulations on pain and emotion.
Chemical Exchange Sensitive MRI: Amide and Amine Protons Mar 11, 2013 from 02:00 PM to 03:00 PM Medical Research Building D Conference Room,
Abstract: Imaging the pH and chemical compositions of the brain is important for understanding brain function and may provide useful information in clinical applications of brain diseases. Chemical exchange of protons between water and biomolecules can be exploited in magnetic resonance imaging (MRI) for measuring pH and metabolite/protein concentration changes which are detected indirectly through water signal with enhanced sensitivity by applying saturation or spin-locking radiofrequency pulses. Exchangeable amide and amine protons are abundant in the brain and have been shown to be promising chemical exchange sites in preclinical studies of brain cancer and stroke. In this talk, I will present the physical principles and the quantification and optimization issues of chemical-exchange sensitive MRI and discuss the in vivo signal source of MRI techniques sensitive to the amide- and amine–water proton exchange.
Chemical Exchange Sensitive MRI: Amide and Amine Protons Mar 11, 2013 from 02:00 PM to 03:00 PM Medical Research Building D Conference Room,
Abstract: Imaging the pH and chemical compositions of the brain is important for understanding brain function and may provide useful information in clinical applications of brain diseases. Chemical exchange of protons between water and biomolecules can be exploited in magnetic resonance imaging (MRI) for measuring pH and metabolite/protein concentration changes which are detected indirectly through water signal with enhanced sensitivity by applying saturation or spin-locking radiofrequency pulses. Exchangeable amide and amine protons are abundant in the brain and have been shown to be promising chemical exchange sites in preclinical studies of brain cancer and stroke. In this talk, I will present the physical principles and the quantification and optimization issues of chemical-exchange sensitive MRI and discuss the in vivo signal source of MRI techniques sensitive to the amide- and amine–water proton exchange.
Bowles Center for Alcohol Studies Seminar Series Mar 11, 2013 from 12:30 PM to 01:30 PM Taylor Hall 124,
Friday ID Conference: HIV in the South Mar 08, 2013 from 08:30 AM to 09:30 AM 1131 Bioinformatics,
Adaora Adimora, MD, to speak at Friday ID Conference on March 8th.
Carolina Systems Genetics Seminar Series Mar 07, 2013 from 03:00 PM to 04:00 PM Pagano Conference Room, LCCC,
David Threadgill, PhD will present the talk "Modeling population exposures in mice: the case of tricholoethylene and Camp Lejeune".
Neuroscience Center Thursday Seminar Series Mar 07, 2013 from 12:30 PM to 01:30 PM 1131 Bioinformatics,
Adam Hantman, PhD, Janelia Farm
2013 BRIC/Radiology Research Day Mar 06, 2013 from 11:30 AM to 06:00 PM NC Cancer Hospital & Bondurant G100,
“PROFILING ATP BINDING IN MYCOBACTERIUM TUBERCULOSIS: Mar 05, 2013 from 11:00 AM to 12:00 PM 1131 Bioinformatics,
CHRISTOPH GRUNDNER, Ph.D. Assistant Professor Department of Global Health University Of Washington, Seattle
Medical Management of Traumatic Brain Injury Mar 04, 2013 from 12:15 PM to 01:00 PM Inpatient Rehabilitation Center, 7th Floor, Memorial Hospital,
Traumatic Brain Injury Discussion Panel Mar 02, 2013 from 01:00 PM to 03:00 PM Inpatient Rehabilitation Center, 7th Floor, Memorial Hospital,
"The Future of Health Information Technology in the US" Mar 01, 2013 from 02:00 PM to 03:30 PM BCBSNC Auditorium, Michael Hooker Research Center,
From federal initiatives to achieve meaningful use, to "tectonic trends," Dr. Friedman will discuss our national progression to a digital health system.
Friday ID Conference: Health Reform and People Living with HIV/AIDS in a Red State Mar 01, 2013 from 08:30 AM to 09:30 AM 1131 Bioinformatics,
Allison Rice, Senior Lecturing Fellow at Duke Law School and Supervising Attorney in the Duke AIDS Legal Project and Duke AIDS Policy Project, to speak at Friday ID Conference on March 1st.
$50K Innovation Pilot Awards- PROPOSAL DEADLINE Mar 01, 2013 12:00 AM n/a,
UNC Health Care and the UNC School of Medicine are pleased to invite their employees to apply for pilot funding for health care innovation efforts. These pilot funds are offered by NC TraCS and the newly formed Center for Innovation of the UNC Health Care System and School of Medicine. Funding is provided by the Center for Innovation. For a copy of the Request for Proposals, including additional information on eligibility and requirements, please click here or copy and paste this link into your browser: http://tracs.unc.edu/begin-research/nc-tracs-pilot-grant-program.html. For questions or assistance please contact either Carol Lewis at carol_lewis@med.unc.edu or Arturo Inda at ainda@unch.unc.edu. All proposals are due on March 1, 2013.
Neuroscience Center Thursday Seminar Series Feb 28, 2013 from 12:30 PM to 01:30 PM 1131 Bioinformatics,
Elizabeth Jonas, MD, Yale University
Cruel Mystery Tour Feb 28, 2013 from 08:00 AM to 01:30 PM UNC Hospitals,
Lupus Foundation of America's Cruel Mystery Lupus Awareness Tour Bus
Pathology & Lab Medicine Grand Rounds,Andra R. Frost, MD, “Targeting Gli1 and Gli-mediated Transcription in Breast Cancer” Feb 28, 2013 from 08:30 AM to 09:30 AM G100 Bondurant,