Ultrasound Molecular Imaging in Disease Detection and Monitoring

BRIC Seminar Series - Presentation by Dr. Juergen K. Willmann, Associate Professor, Stanford University School of Medicine Dept. of Radiology

When Oct 09, 2013
from 01:00 PM to 02:00 PM
Where 1131 Bioinformatics
Contact Name
Contact Phone 919-966-4397
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Abstract:

Ultrasound imaging is a widely available, relatively inexpensive, and real-time imaging modality that does not expose patients to radiation and which is the first-line imaging modality for assessment of many organs. Through the introduction of ultrasound contrast agents, the sensitivity and specificity of ultrasound for detection and characterization of focal lesions has been substantially improved. Recently, targeted contrast-enhanced ultrasound imaging (ultrasound molecular imaging) has gained great momentum in preclinical research by the introduction of ultrasound contrast agents that are targeted at molecular markers over-expressed on the vasculature of certain diseases. By combining the advantages of ultrasound with the ability to image molecular signatures of diseases, ultrasound molecular imaging has great potential as a highly sensitive and quantitative method that could be used for various clinical applications, including screening for early stage disease (such as cancer), characterization of focal lesions, quantitative monitoring of disease process at the molecular level, assisting in image-guided procedures, and confirming target expression for treatment planning and monitoring.

In this talk the concepts of ultrasound molecular imaging are reviewed along with a discussion on current applications in preclinical and clinical research.

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