Curriculum Vitae

Heather G. Baudet

University of North Carolina

School of Medicine

101 Manning Drive

Chapel Hill, NC 27599

Tel. 919-225-6465

E-mail: hbaudet@nc.rr.com

EDUCATION

University of North Carolina School of Medicine
Chapel Hill, North Carolina

M.D. May 2007

University of North Carolina School of Medicine
Chapel Hill, North Carolina

Ph.D. May 2005

Randolph-Macon Woman’s College
Lynchburg, Virginia
B.S. in Biology magna cum laude, 1996

University of North Carolina - Charlotte
Charlotte, North Carolina
Courses in History, Physics and Sociology, 1994-1996

St. John’s University

Jamaica, New York

Courses in Literature, Mathematics and Religion, 1991-1992

HONORS AND AWARDS

University of North Carolina School of Medicine

· Pierre Morell Neurobiology Curriculum Research Day Award – 1^st place 2004

· Awarded National Alliance for Autism Research Grant for Biomedical Research in Autism Spectrum Disorders, 2001-2003.

· Michiko Kuno Research Award, 2000

· John B. Graham Student Research Society of the University of North Carolina at Chapel Hill School of Medicine, 2000.

· Grover Dale Medical Scholarship, 1997

· Research Fellowship, 1996, 1999 and 2000
University of North Carolina School of Medicine: Neurobiology Program

Randolph-Macon Woman’s College

· Departmental Honors in Biology, 1996

· Phi Beta Kappa, 1996

· Magna Cum Laude, 1996

· R-MWC Centennial Scholarship Award, 1992-1996

· Rated “1/Excellent” for writing skills, 1995 and 1996

· Old Dominion Athletic Conference Scholar Athlete Award, 1993 and 1994

· Dean's List seven semesters

ACTIVITIES

University of North Carolina School of Medicine

· American Medical Association 1999-present

· American Medical Student Association 1999-2007

· Tour Guide 1999

Randolph Macon Woman’s College

· Curriculum Committee 1994-1996

Chair 1995-1996, Assistant Chair 1994-1995

· Academic Programming Committee, 1994-1996

· Internship with Dr. Lori Schneider, 1995

Neurology – Davidson, NC.

· Health Advisory Board, 1994-1995

· Internship with Dr. George Hurt, 1994 - 1995
Neurosurgery – Lynchburg, VA.

· Tennis Team, 1992-1994

· Basketball Team, 1993-1994

· Fencing Team, 1992-1993

RESEARCH

Publications:

Parnell SE, Dehart DB, Wills TA, Chen SY, Hodge CW, Besheer J, Waage-Baudet HG, Charness ME, Sulik KK. Maternal oral intake mouse model for fetal alcohol spectrum disorders: ocular defects as a measure of effect. Alcohol Clin Exp Res. 2006 Oct;30(10):1791-8

THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, Brain malformations in a mouse model for the Smith-Lemli-Opitz syndrome and their implications for autism - Dissertation, Waage-Baudet, Heather, Publication Date: 9/2005

Waage-Baudet H, Dunty WC Jr, Dehart DB, Hiller S, Sulik KK.Immunohistochemical and microarray analyses of a mouse model for the smith-lemli-opitz syndrome. Dev Neurosci. 2005;27(6):378-96.

Lauder JM, Waage-Baudet H, Seidel H, Crawley JN, Perez A, Moy SS. Differential Effects of the Fragile-X Mutation on Gene Expression and Behavioral Phenotype in Mice on FVB and C57BL/6 Backgrounds. Society for Neuroscience's 34th Annual Meeting. San Diego, CA 2004 (Poster).

Lauder, J., Waage-Baudet H, and Moy, SS. (USA): Modeling genetic susceptibility to autism in mouse models of Fragile-X and Smith-Lemli-Opitz syndrome. Fifteenth Biennial Meeting of the International Society for Developmental Neuroscience. Edinburgh, Scotland. 2004 (Abstract).

Waage-Baudet H, Lauder JM, Dehart DB, Kluckman K, Hiller S, Tint GS, Sulik KK. Abnormal serotonergic development in a mouse model for the Smith-Lemli-Opitz syndrome: implications for autism. Int J Dev Neurosci. 2003 Dec;21(8):451-9.

Waage-Baudet, H.G., Twenty-third David W. Smith Workshop on Malformations and Morphogenesis (Abstract) 2002.

Fitzky BU, Moebius FF, Asaoka H, Waage-Baudet H, Xu L, Xu G, Maeda N, Kluckman K, Hiller S, Yu H, Batta AK, Shefer S, Chen T, Salen G, Sulik K, Simoni RD, Ness GC, Glossmann H, Patel SB, Tint GS. 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. J Clin Invest. 2001 Sep;108(6):905-15

G.S. Tint, H. Waage, K. Sulik, F. Moebius, B. Fitzky, H. Glossmann, S. Shefer, G. Salen, K. Kluckman, N. Maeda. A mouse model for the Smith-Lemli-Opitz Syndrome (SLOS). Dept of Medicine VA Medical Center, East Orange, NJ and UMDNJ-NJ Medical School, Newark, NJ, Univ of North Carolina, NC and Universitat Innsbruck, Innsbruck, Austria. Society for Human Genetics, October 1999 (Abstract).

Crews FT. Waage HG. Wilkie MB. Lauder JM. Ethanol pretreatment enhances NMDA excitotoxicity in biogenic amine neurons: protection by brain derived neurotrophic factor. Alcoholism: Clinical & Experimental Research. 23(11):1834-42, 1999 Nov.

H.G. Waage, J.R. Yates, A.R. Blight, and M.P. Heyes. Intraspinal infusion of quinolinic acid produces inflammatory lesions and behavioral deficits in guinea pigs. Div. Neurosurg., Univ. NC, Chapel Hill and Lab of Neurotoxicology, NIMH, Bethesda MD. Society for Neuroscience, November 1997 (Abstract).

Presentations:

Pierre Morell Neurobiology Curriculum Research Day, Brain malformations in a mouse model for the Smith-Lemli-Opitz syndrome and their implications for autism, Waage-Baudet, H, Publication Date: 2005

NIEHS, Microarray,and Immunohistochemical Analyses of a Mouse Model for the Smith-Lemli-Opitz Syndrome: Implications for Autism, Waage-Baudet H, Publication Date: 2004

UNC NDRC Autism Forum, Microarray,and Immunohistochemical Analyses of a Mouse Model for the Smith-Lemli-Opitz Syndrome: Implications for Autism, Waage-Baudet H, Publication Date: 2004

Twenty-third David W. Smith Workshop on Malformations and Morphogenesis, Abnormal Serotonergic Development in a mouse model for SLOS, Waage-Baudet, H.G, Publication Date: 2002

UNC Neuroscience Center Seminar Series, Autism, serotonin and SLOS, Waage-Baudet H, Publication Date: 2002

NIH Autism Coordinating Committee's 2001 Scientific Conference on "Potential Cellular and Molecular Mechanisms in Autism and Related Disorders.", Brain Malformations in a Mouse Model for Smith-Lemli-Opitz Syndrome - Implications for Autism, Waage-Baudet, H.G., Lauder, J.M., Sulik, K.K, Publication Date: 2001

Waage-Baudet, H.G., Tint, G.S., Maeda N., Lauder, J.M., Sulik K.K. Brain Malformations in the 7-DHCR Mouse Model - Implications for the behavioral phenotype seen in SLOS and Autism. The Fourth International Smith-Lemli-Opitz/RSH Syndrome Scientific Symposium Detroit, Michigan June 22-23, 2001.

Waage, H.G., Tint G.S., Maeda N., Goodrum J., Sulik K.K. Generation of a mouse model for the Smith-Lemli-Opitz syndrome – targeted disruption of the Delta-7-sterol reductase gene in mice. Student research day at the university of North Carolina, School of Medicine. January 19, 2000.

Waage, H.G., Tint, G.S., Moebius, F.F., Glossmann, H., Maeda, N., Sulik, K. Targeted disruption of the D-7-sterol reductase gene in mice. Second International Scientific Symposium on Smith-Lemli-Opitz/RSH Syndrome. June 1999.

Research Experience:

· Brain Malformations in a Mouse Model for Smith-Lemli-Opitz Syndrome and their implications for Autism

Preceptors:

Nobuyo Maeda, Ph.D.
Department of Pathology University of North Carolina - Chapel Hill, NC.

Kathleen Sulik, Ph.D.

Department of Cell Biology and Anatomy, University of North Carolina - Chapel Hill, NC.

May1998 – 2005
Description: Targeted disruption of the D-7-sterol reductase gene in mice to create a mouse model for the Smith-Lemli-Opitz/RSH Syndrome and characterization of the mouse model.

· NMDA Mediated Excitotoxicity in Biogenic Amines

Preceptors:	Fulton T. Crews, Ph.D. Center for Alcohol Studies at the University of North Carolina, Chapel Hill
May1997 – August 1997 Description: An assessment of ethanol induced NMDA mediated excitotoxicity in biogenic amines and the protection by brain derived neurotrophic factor.

· The Effects of Quinolinic Acid in Spinal Cord Injury

Preceptors:	Andrew R. Blight, Ph.D. Department of Neurosurgery at the University of North Carolina School of Medicine
August 1996 – May 1997 Description: An assessment of the role of quinolinic acid in spinal cord injury by intraspinal infusion of quinolinic acid in guinea pigs.

· A study of the apoptosis in bacterial colonies

Preceptors:

Judith Palmer, Ph.D.
Department of Biology at Randolph-Macon Woman’s College

September 1995 – May 1996
Funding: Randolph-Macon Woman’s College Honors program in Biology

Description: A look at the effects of environmental stress and its ability to induce apoptosis in Escherichia coli

TEACHING EXPERIENCE/EMPLOYMENT

March – May, 2003	Medical Neurobiology Lab Instructor University of North Carolina School of Medicine Chapel Hill, North Carolina
March – May, 2002	Medical Neurobiology Teacher Assistant University of North Carolina School of Medicine Chapel Hill, North Carolina
March – May, 2000	Medical Neurobiology Teacher Assistant University of North Carolina School of Medicine Chapel Hill, North Carolina
August-May 1995-1996	Writing Lab Tutor Randolph-Macon Woman’s College Lynchburg, Virginia Assisted students with scientific writing skills
August – May, 1994-1995 1995-1996	Ethyl Center Tutor Randolph-Macon Woman’s College Lynchburg, Virginia Assisted students in the areas of Statistics, Chemistry and Biology.
January-May, 1994	Volunteer Central Virginia Training Center Lynchburg, Virginia Worked with children with developmental disabilities.
May- August, 1993	Volunteer University Hospital Charlotte, North Carolina Assisted nursing and hospital staff with patient care.

PROFESSIONAL MEMBERSHIPS

Society for Neuroscience, 1996-1997

American Medical Student Association, 1999- present
American Medical Association 1999- present

PERSONAL INTERESTS

Painting, Creative Writing, Computers, Tennis, Foreign travel