Date: Wednesday, October 30, 2013
Time: 11:30 a.m. to 12:30 p.m.
Location: Brinkhous-Bullitt Room 219
Clinical trials are an established component of research. Recently, the impact of trials has been hindered by the increasing cost of participant enrollment and follow-up, and the limited applicability of trial findings to the population of individuals affected by the condition of interest. Conducting trials that are quicker, more generalizable, and with lower cost per enrollee is likely to be a major focus of NIH and PCORI over the next several years. These efforts are called ‘pragmatic clinical trials’ or ‘large simple trials.’ NIH has already invested in such trials through their ‘collaboratory’ program (https://commonfund.nih.gov/hcscollaboratory/). Additional RFA’s are expected later this year. PCORI’s clinical data research network infrastructure (CDRN) program is designed to support such work.
TraCS will sponsor a seminar on pragmatic trials on October 30, 11:30 a.m. to 12:30 p.m. Speakers will discuss what is different about pragmatic trials in terms of setting, design, and appropriate questions, including the informatics infrastructure needed to conduct this work. Current examples of pragmatic trials in the US may involve conduct within the setting of large integrated health care delivery systems, raising issues of engagement with providers, administrators, and patients in order to successfully enroll and complete follow-up in a timely and efficient manner.
The session will have several short presentations, with much of the time devoted to discussion. Bring your ideas!