{"id":2116,"date":"2023-02-06T10:39:58","date_gmt":"2023-02-06T15:39:58","guid":{"rendered":"https:\/\/www.med.unc.edu\/alcohol\/?post_type=directory&p=2116"},"modified":"2023-02-07T10:43:53","modified_gmt":"2023-02-07T15:43:53","slug":"ryan-vetreno-ph-d","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/alcohol\/directory\/ryan-vetreno-ph-d\/","title":{"rendered":"Ryan Vetreno, Ph.D."},"content":{"rendered":"

Research Interests<\/h2>\n

My research interests involve investigation of proinflammatory neuroimmune and epigenetic mechanisms in animal models of developmental neurobiology and neurodegeneration, including (1) alcohol pharmacology, (2) adolescent neurodevelopment, (3) cholinergic system and neurocircuitry, and (4) Alzheimer\u2019s disease. A major focus of the laboratory is elucidation of neuroimmune and epigenetic mechanisms underlying adolescent binge alcohol-induced disruption of basal forebrain cholinergic neurocircuitry in adulthood. A second focus of the laboratory is investigation of lasting adolescent binge drinking-induced neuroimmune priming as a novel etiological factor contributing to the onset and progression of basal forebrain neuropathology in Alzheimer\u2019s disease. Our laboratory combines ex vivo and in vivo rodent models of alcohol abuse and Alzheimer\u2019s disease with innovative molecular techniques.<\/p>\n

 <\/p>\n

Publications<\/h2>\n

Vetreno, R.P.<\/strong>, Qin, L., Coleman, L.G., & Crews, F.T.\u00a0 (2021). Increased Toll-like receptor-MyD88-NFkB-proinflammatory neuroimmune signaling in the orbitofrontal cortex of human alcohol use disorder. ACER<\/em>, PMID<\/u>: 34415075.<\/p>\n

Liu, W., Rohlman, A.R., Vetreno, R.P.<\/strong>, & Crews, F.T. (2021). Expression of oligodendrocyte and oligoprogenitor cell proteins in frontal cortical white and gray matter: Impact of adolescent development and ethanol exposure. Front Pharmacol<\/em>, PMID<\/u>: 34025418.<\/p>\n

Qin, L., Zou, J., Barnett, A., Vetreno, R.P.<\/strong>, Crews, F.T., & Coleman, L.G. (2021). TRAIL mediates neuronal death in AUD: A link between neuroinflammation and neurodegeneration. Int J Mol Sci<\/em>, PMID<\/u>: 33806288.<\/p>\n

Crews, F.T., Fisher, R., Deason, C., & Vetreno, R.P. <\/strong>(2021). Loss of basal forebrain cholinergic neurons following adolescent binge ethanol exposure: Recovery with the cholinesterase inhibitor galantamine. Front Behav Neurosci<\/em>, PMID<\/u>: 33716687.<\/p>\n

 <\/p>\n

Click here to see full list of publications<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Research Interests My research interests involve investigation of proinflammatory neuroimmune and epigenetic mechanisms in animal models of developmental neurobiology and neurodegeneration, including (1) alcohol pharmacology, (2) adolescent neurodevelopment, (3) cholinergic system and neurocircuitry, and (4) Alzheimer\u2019s disease. A major focus of the laboratory is elucidation of neuroimmune and epigenetic mechanisms underlying adolescent binge alcohol-induced disruption … Read more<\/a><\/p>\n","protected":false},"featured_media":1356,"template":"","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"class_list":["post-2116","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"\nRyan Vetreno, Ph.D. | Bowles Center for Alcohol Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/alcohol\/directory\/ryan-vetreno-ph-d\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ryan Vetreno, Ph.D. | Bowles Center for Alcohol Studies\" \/>\n<meta property=\"og:description\" content=\"Research Interests My research interests involve investigation of proinflammatory neuroimmune and epigenetic mechanisms in animal models of developmental neurobiology and neurodegeneration, including (1) alcohol pharmacology, (2) adolescent neurodevelopment, (3) cholinergic system and neurocircuitry, and (4) Alzheimer\u2019s disease. 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