{"id":2587,"date":"2025-02-14T15:58:21","date_gmt":"2025-02-14T20:58:21","guid":{"rendered":"https:\/\/www.med.unc.edu\/alcohol\/?page_id=2587"},"modified":"2025-02-18T11:54:01","modified_gmt":"2025-02-18T16:54:01","slug":"alison-roland-ph-d","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/alcohol\/alison-roland-ph-d\/","title":{"rendered":"Alison Roland, Ph.D."},"content":{"rendered":"

\"\"<\/p>\n

 <\/p>\n

Research Assistant Professor<\/b>
\nBowles Center for Alcohol Studies
\nDepartment of Psychiatry<\/p>\n

Office |<\/b> 5023 Thurston-Bowles Bldg, CB #7178
\nEmail |<\/b> alison_roland@med.unc.edu<\/a>
\nLab Website | <\/b>Kash Lab<\/a><\/p>\n

Biosketch <\/strong>| Roland Biosketch<\/a><\/p>\n

 <\/p>\n

Research Interests<\/strong><\/p>\n

Dr. Roland\u2019s research in the Kash lab focuses on the neural mechanisms underlying alcohol use disorder, and in particular how stress and affective dysregulation precipitate and perpetuate heavy alcohol consumption. Her work integrates a variety of molecular, surgical, and pharmacological approaches in mice, including adeno-associated virus-mediated genetic manipulations, fiber photometry using genetically encoded calcium sensors, immunohistochemical staining, imaging of cleared whole-brain tissue, and behavioral studies in mouse models that recapitulate aspects of alcohol use disorder. Using these techniques, she focuses on the neuropeptides and neurocircuitry within the extended amygdala and other brain regions that drive maladaptive affective behaviors and escalated drinking, with a focus on identifying therapeutically relevant molecular targets. Recently, Dr. Roland led a collaborative study investigating whole-brain networks involved in alcohol withdrawal, identifying the cortical amygdala as a key brain region that drives large-scale changes in neural activity during withdrawal. This work established the cortical amygdala as a novel anatomical hub for alcohol drinking behavior. Dr. Roland\u2019s ongoing research focuses on the role of various amygdalar subnuclei in negative affective behaviors and alcohol odor cue-induced drinking, as well as the role of neuropeptides in shaping interregional communication. In addition to her research, Dr. Roland mentors undergraduate and graduate students in the Kash lab.<\/p>\n

 <\/p>\n

Recent Publications<\/strong><\/p>\n

https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/alison.roland.1\/bibliography\/public\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

  Research Assistant Professor Bowles Center for Alcohol Studies Department of Psychiatry Office | 5023 Thurston-Bowles Bldg, CB #7178 Email | alison_roland@med.unc.edu Lab Website | Kash Lab Biosketch | Roland Biosketch   Research Interests Dr. Roland\u2019s research in the Kash lab focuses on the neural mechanisms underlying alcohol use disorder, and in particular how stress … Read more<\/a><\/p>\n","protected":false},"author":15215,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2587","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"\nAlison Roland, Ph.D. | Bowles Center for Alcohol Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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