{"id":2301,"date":"2023-05-02T13:36:32","date_gmt":"2023-05-02T17:36:32","guid":{"rendered":"https:\/\/www.med.unc.edu\/alcohol\/?p=2301"},"modified":"2023-05-02T13:36:32","modified_gmt":"2023-05-02T17:36:32","slug":"dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/","title":{"rendered":"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA"},"content":{"rendered":"<p>Congratulations to Dr. Jessica Hoffman, a postdoctoral fellow in Dr. <a href=\"https:\/\/hodgelab.web.unc.edu\/\">Clyde Hodge\u2019s lab<\/a>, for receiving a K99\/R00 Pathway to Independence Award from the NIAAA. The prestigious K99\/R00 award provides 2 years of support for Dr. Hoffman\u2019s continued postdoctoral research at UNC (K99 phase) followed by 3 years of independent funding after she transitions to a tenure-track faculty position (R00 phase).<\/p>\n<p>Dr. Hoffman\u2019s preclinical project, entitled \u201cA novel mechanism of dependence-induced escalated alcohol self-administration,\u201d will investigate the novel mechanistic role of the auxiliary protein <em>transmembrane AMPAR regulatory protein gamma 8<\/em> (TARP \u03b3-8) in alcohol dependence. During the K99 phase, Dr. Hoffman will extend her training to include use of a novel multi-spectral four-channel fiber photometry platform with Dr. Ian Shih and evaluate a role of TARP \u03b3-8 in dependence-induced escalation of operant alcohol self-administration. During the R00 phase, Dr. Hoffman will integrate these methods to analyze the role of TARP \u03b3-8 in neural circuits that regulate escalated alcohol use during dependence. This work will move the field forward in understanding molecular mechanisms of alcohol dependence and has high translational value for developing novel treatments for individuals suffering from alcohol use disorder.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations to Dr. Jessica Hoffman, a postdoctoral fellow in Dr. Clyde Hodge\u2019s lab, for receiving a K99\/R00 Pathway to Independence Award from the NIAAA. The prestigious K99\/R00 award provides 2 years of support for Dr. Hoffman\u2019s continued postdoctoral research at UNC (K99 phase) followed by 3 years of independent funding after she transitions to a &hellip; <a href=\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/\" aria-label=\"Read more about Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA\">Read more<\/a><\/p>\n","protected":false},"author":15215,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-2301","post","type-post","status-publish","format-standard","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA | Bowles Center for Alcohol Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA | Bowles Center for Alcohol Studies\" \/>\n<meta property=\"og:description\" content=\"Congratulations to Dr. Jessica Hoffman, a postdoctoral fellow in Dr. Clyde Hodge\u2019s lab, for receiving a K99\/R00 Pathway to Independence Award from the NIAAA. The prestigious K99\/R00 award provides 2 years of support for Dr. Hoffman\u2019s continued postdoctoral research at UNC (K99 phase) followed by 3 years of independent funding after she transitions to a &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/\" \/>\n<meta property=\"og:site_name\" content=\"Bowles Center for Alcohol Studies\" \/>\n<meta property=\"article:published_time\" content=\"2023-05-02T17:36:32+00:00\" \/>\n<meta name=\"author\" content=\"Jennie Vaughn\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jennie Vaughn\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/\"},\"author\":{\"name\":\"Jennie Vaughn\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/person\/10218eb7b170c65af8ee8f6a42f8e769\"},\"headline\":\"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA\",\"datePublished\":\"2023-05-02T17:36:32+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/\"},\"wordCount\":205,\"publisher\":{\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#organization\"},\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/\",\"url\":\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/\",\"name\":\"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA | Bowles Center for Alcohol Studies\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#website\"},\"datePublished\":\"2023-05-02T17:36:32+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/alcohol\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/alcohol\/\",\"name\":\"Bowles Center for Alcohol Studies\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/alcohol\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#organization\",\"name\":\"Bowles Center for Alcohol Studies\",\"url\":\"https:\/\/www.med.unc.edu\/alcohol\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.med.unc.edu\/alcohol\/wp-content\/uploads\/sites\/515\/2018\/05\/Bowles-Center-for-Alcohol-Studies_logo_rgb_h.png\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/alcohol\/wp-content\/uploads\/sites\/515\/2018\/05\/Bowles-Center-for-Alcohol-Studies_logo_rgb_h.png\",\"width\":1489,\"height\":151,\"caption\":\"Bowles Center for Alcohol Studies\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/person\/10218eb7b170c65af8ee8f6a42f8e769\",\"name\":\"Jennie Vaughn\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ffcab8006ce80c67278642429f926aff8ffcb46de7872209afcec6f56093f60e?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ffcab8006ce80c67278642429f926aff8ffcb46de7872209afcec6f56093f60e?s=96&d=mm&r=g\",\"caption\":\"Jennie Vaughn\"},\"description\":\"School of Social Work\",\"url\":\"https:\/\/www.med.unc.edu\/alcohol\/author\/jsvaughn\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA | Bowles Center for Alcohol Studies","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/","og_locale":"en_US","og_type":"article","og_title":"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA | Bowles Center for Alcohol Studies","og_description":"Congratulations to Dr. Jessica Hoffman, a postdoctoral fellow in Dr. Clyde Hodge\u2019s lab, for receiving a K99\/R00 Pathway to Independence Award from the NIAAA. The prestigious K99\/R00 award provides 2 years of support for Dr. Hoffman\u2019s continued postdoctoral research at UNC (K99 phase) followed by 3 years of independent funding after she transitions to a &hellip; Read more","og_url":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/","og_site_name":"Bowles Center for Alcohol Studies","article_published_time":"2023-05-02T17:36:32+00:00","author":"Jennie Vaughn","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jennie Vaughn","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/#article","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/"},"author":{"name":"Jennie Vaughn","@id":"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/person\/10218eb7b170c65af8ee8f6a42f8e769"},"headline":"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA","datePublished":"2023-05-02T17:36:32+00:00","mainEntityOfPage":{"@id":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/"},"wordCount":205,"publisher":{"@id":"https:\/\/www.med.unc.edu\/alcohol\/#organization"},"articleSection":["News"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/","url":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/","name":"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA | Bowles Center for Alcohol Studies","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/alcohol\/#website"},"datePublished":"2023-05-02T17:36:32+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/alcohol\/dr-jessica-hoffman-receives-k99-r00-pathway-to-independence-award-from-the-niaaa\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/alcohol\/"},{"@type":"ListItem","position":2,"name":"Dr. Jessica Hoffman receives K99\/R00 Pathway to Independence Award from the NIAAA"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/alcohol\/#website","url":"https:\/\/www.med.unc.edu\/alcohol\/","name":"Bowles Center for Alcohol Studies","description":"","publisher":{"@id":"https:\/\/www.med.unc.edu\/alcohol\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/alcohol\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.med.unc.edu\/alcohol\/#organization","name":"Bowles Center for Alcohol Studies","url":"https:\/\/www.med.unc.edu\/alcohol\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/logo\/image\/","url":"https:\/\/www.med.unc.edu\/alcohol\/wp-content\/uploads\/sites\/515\/2018\/05\/Bowles-Center-for-Alcohol-Studies_logo_rgb_h.png","contentUrl":"https:\/\/www.med.unc.edu\/alcohol\/wp-content\/uploads\/sites\/515\/2018\/05\/Bowles-Center-for-Alcohol-Studies_logo_rgb_h.png","width":1489,"height":151,"caption":"Bowles Center for Alcohol Studies"},"image":{"@id":"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/person\/10218eb7b170c65af8ee8f6a42f8e769","name":"Jennie Vaughn","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/alcohol\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/ffcab8006ce80c67278642429f926aff8ffcb46de7872209afcec6f56093f60e?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ffcab8006ce80c67278642429f926aff8ffcb46de7872209afcec6f56093f60e?s=96&d=mm&r=g","caption":"Jennie Vaughn"},"description":"School of Social Work","url":"https:\/\/www.med.unc.edu\/alcohol\/author\/jsvaughn\/"}]}},"featured_image":false,"featured_image_medium":false,"featured_image_medium_large":false,"featured_image_large":false,"featured_image_thumbnail":false,"featured_image_alt":false,"category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/alcohol\/category\/news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/posts\/2301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/users\/15215"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/comments?post=2301"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/posts\/2301\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/media?parent=2301"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/categories?post=2301"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/alcohol\/wp-json\/wp\/v2\/tags?post=2301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}