{"id":305,"date":"2017-09-21T18:55:00","date_gmt":"2017-09-21T22:55:00","guid":{"rendered":"https:\/\/med.sites.unc.edu\/alcohol\/joyce-besheer-receives-nih-grant-to-study-brain-circuits-affected-by-ptsd-and-alcohol-use\/"},"modified":"2017-12-11T16:44:08","modified_gmt":"2017-12-11T21:44:08","slug":"joyce-besheer-receives-nih-grant-to-study-brain-circuits-affected-by-ptsd-and-alcohol-use","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/alcohol\/joyce-besheer-receives-nih-grant-to-study-brain-circuits-affected-by-ptsd-and-alcohol-use\/","title":{"rendered":"Joyce Besheer receives NIH grant to study brain circuits affected by PTSD and alcohol use"},"content":{"rendered":"<p><!-- description --><\/p>\n<p class=\"lead\">\n<div class=\"image-section\">\n<\/div>\n<p>The National Institute on Alcohol Abuse and Alcoholism has awarded a $1.9 million, 5-year grant to Joyce Besheer, PhD, of the Bowles Center for Alcohol Studies, to study the underlying neuropathy of post-traumatic stress disorder and alcohol abuse.<\/p>\n<\/p>\n<dl class=\"portalMessage info\" id=\"kssPortalMessage\">\n<dt\/>\n<dd\/><\/dl>\n<div id=\"viewlet-above-content-body\"\/>\n<div id=\"content-area\">\n<div class=\"newsImageContainer somLinkedContent\"><a class=\"target link-overlay\" href=\"http:\/\/news.unchealthcare.org\/som-vital-signs\/2017\/sept-21\/nih-grant-for-unc-scientists-to-study-brain-circuits-affected-by-comorbid-ptsd-and-alcohol-use\/image2\/image_view_fullscreen\" id=\"parent-fieldname-image\" rel=\"#pb_1\"><img loading=\"lazy\" decoding=\"async\" alt=\"Besheers receives NIH grant to study brain circuits affected by PTSD and alcohol use\" height=\"400\" src=\"http:\/\/news.unchealthcare.org\/som-vital-signs\/2017\/sept-21\/nih-grant-for-unc-scientists-to-study-brain-circuits-affected-by-comorbid-ptsd-and-alcohol-use\/@@images\/c2d92baa-5c04-4f6c-a860-f3c9ab29bada.jpeg\" title=\"Besheers receives NIH grant to study brain circuits affected by PTSD and alcohol use\" width=\"225\"\/> <\/a> <span class=\"image-caption\"><a class=\"target link-overlay\" href=\"http:\/\/news.unchealthcare.org\/som-vital-signs\/2017\/sept-21\/nih-grant-for-unc-scientists-to-study-brain-circuits-affected-by-comorbid-ptsd-and-alcohol-use\/image2\/image_view_fullscreen\" id=\"parent-fieldname-image\" rel=\"#pb_2\"><img decoding=\"async\" src=\"http:\/\/news.unchealthcare.org\/som-vital-signs\/2017\/sept-21\/search_icon.png\"\/>click to enlarge<\/a><span id=\"parent-fieldname-imageCaption2-af8142441a95494691530280fc5de87d\"> Joyce Besheer, PhD <\/span> <\/span><\/div>\n<div class=\"plain\" id=\"parent-fieldname-text\">\n<p>Post-Traumatic stress disorder (PTSD) is a debilitating and enduring disorder that develops in some individuals following intense trauma. It is also associated with problem drinking and alcohol use disorder. Joyce Besheer, PhD, of UNC\u2019s Bowles Center for Alcohol Studies, has been awarded a $1.9 million, 5-year NIH grant from the National Institute on Alcohol Abuse and Alcoholism to study the interaction between PTSD and alcohol abuse.<\/p>\n<p>\u201cAlcohol and stress share the brain circuitry that contributes to the co-occurrence of these disorders,\u201d Besheer said. \u201cBut, how brain circuitry changes in PTSD to increase the risk of alcohol use disorder is not well understood.\u201d<\/p>\n<p>Besheer and her team have been using existing animal models of PTSD to examine how exposure to stressful events can produce long-lasting behavioral and neurocircuitry changes that mimic PTSD symptom clusters, and how these symptoms may contribute to increased alcohol use.<\/p>\n<p>\u201cInitially, we will determine which PTSD-like behavioral characteristics are predictive of escalated drinking patterns. From there we will examine adaptations in the circuitry of areas of the brain involved in emotional memory and cognition that may drive escalations in alcohol use,\u201d Besheer said.<\/p>\n<p>Ultimately, the goal of this project is to provide a better understanding of the neural mechanisms underlying how PTSD can lead to alcohol use disorders, in the hope that this understanding will lead to new therapeutic options<\/p>\n<\/p>\n<p><a class=\"external-link\" href=\"http:\/\/news.unchealthcare.org\/som-vital-signs\/2017\/sept-21\/nih-grant-for-unc-scientists-to-study-brain-circuits-affected-by-comorbid-ptsd-and-alcohol-use?utm_source=vs-email&#038;utm_medium=email&#038;utm_campaign=38\" target=\"_self\" title=\"\">http:\/\/news.unchealthcare.org\/som-vital-signs\/2017\/sept-21\/nih-grant-for-unc-scientists-to-study-brain-circuits-affected-by-comorbid-ptsd-and-alcohol-use?utm_source=vs-email&#038;utm_medium=email&#038;utm_campaign=38<\/a><\/p>\n<\/p><\/div>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>The National Institute on Alcohol Abuse and Alcoholism has awarded a $1.9 million, 5-year grant to Joyce Besheer, PhD, of the Bowles Center for Alcohol Studies, to study the underlying neuropathy of post-traumatic stress disorder and alcohol abuse. click to enlarge Joyce Besheer, PhD Post-Traumatic stress disorder (PTSD) is a debilitating and enduring disorder that &hellip; <a href=\"https:\/\/www.med.unc.edu\/alcohol\/joyce-besheer-receives-nih-grant-to-study-brain-circuits-affected-by-ptsd-and-alcohol-use\/\" aria-label=\"Read more about Joyce Besheer receives NIH grant to study brain circuits affected by PTSD and alcohol use\">Read more<\/a><\/p>\n","protected":false},"author":63912,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-305","post","type-post","status-publish","format-standard","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Joyce Besheer receives NIH grant to study brain circuits affected by PTSD and alcohol use | Bowles Center for Alcohol Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/alcohol\/joyce-besheer-receives-nih-grant-to-study-brain-circuits-affected-by-ptsd-and-alcohol-use\/\" \/>\n<meta property=\"og:locale\" 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