Samuel McLean

Professor of Anesthesiology and Emergency Medicine
Vice Chair for Research

Education:

Residency: Emergency Medicine, Boston Medical Center (2001)
Residency: Internal Medicine, Massachusetts General Hospital (1998)
Post-Graduate: MPH , University of Michigan (1995)
Medical School: MD, University of Michigan (1995)
Undergraduate: BA Comparative Religion and Philosophy, Dartmouth College (1990)

Notable Publications
and Presentations

Textbook Contributions
McLean SA. Neurobiologic mechanisms of whiplash . In: Whiplash injury: Perspectives on the development of chronic pain, Troels S. Jensen, Dennis Turk, and Helge Kasch (eds.) , Philadelphia, Pennsylvania, IASP press (2016) pp 155-169.
Bortsov AV, Millikan RC, Belfer I, Boortz-Marx RL, Arora H, McLean SA . Genetic polymorphisms in mu-opioid receptor gene and breast cancer survival. In: Morphine and Metastases, Marie-Odile Parat (ed.) , New York, New York, Springer (2013) pp 95-112.
Refereed Publications
Jones CW, others and McLean SA. Epidemiology of Intravenous Fluid Use for the Treatment of Headache in the Emergency Department: Findings from the National Hospital Ambulatory Medical Care Survey. American Journal of Emergency Medicine 2017.
Kent M, Tighe P, Belfer I, Brennan TJ, Bruehl S, Brummett C, Buckenmaier C, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon D, Hurley R, Kehlet H, Loeser J, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, T. The ACTTION-American Pain Society-American Academy of Pain Medicine Pain Pain Taxonomy (AAAPT): An Evidence-Based and Multidimensional Approach to Classifying Acute Pain Conditions. Pain Medicine 2017.
Mauck MC, Smith J, Liu AY, Jones SW, Shupp JW, Villard MA, Williams F, Hwang J, Karlnoski R, Smith DJ, Cairns BA, Kessler RC, McLean SA. Chronic pain and itch are common, morbid sequelae among individuals who receive tissue autograft after major thermal burn injury. Clin J Pain. 2016.
Wang X, Xie H, Cotton AS, Brickman KR, Lewis TL, Wall JT, Tamburrino MB, Bauer WR, Law K, McLean SA, Liberzon I. Early changes in emotion processing after mild traumatic brain injury following motor vehicle collision. Journal of Neurotrauma 2016.
Linnstaedt SD, Walker MG, Riker KD, Nyland JE, Hu JM, Rossi C, Swor RA, Jones JS, Diatchenko L, Bortsov AV, Peak DA, McLean SA. Genetic variant rs3750625 in the 3?UTR of ADRA2A affects stress dependent acute pain severity after trauma and alters a microRNA-34a regulatory site. Pain2016.
Linnstaedt SD, Hu JunMei, Liu AY, Soward AC, Bollen KA, Wang HE, Hendry PL, Zimny E, Lewandowski C, Velilla MA, Damiron K, Pearson C, Domeier R, Kaushik S, Feldman J, Rosenberg M, Jones J, Swor R, Rathlev N, McLean SA. Methodology of the AA CRASH Prospective Observational Study Evaluating the Incidence and Pathogenesis of Chronic Pain and Adverse Psychological Outcomes in African Americans following Motor Vehicle Collision. BMJ Open 2016.
Linnstaedt SD, Riker KD, Walker MG, Nyland JE, Zimny E, Lewandowski C, Hendry PL, Damiron K, Pearson C, Velilla MA, Jones J, Swor RA, Domeier R, McLean SA. microRNA-320a predicts chronic axial and widespread pain development following motor vehicle collision in a stress-dependent manner. JOSPT 2016; 46: 911-919.
Beaudoin FL, Gutman R, Merchant RC, Melissa CA, Swor RA, Jones JS, Lee DC, Peak DA, Domeier RM, Rathlev NK, McLean SA. Persistent pain after motor vehicle collision: Comparative effectiveness of opioids versus non-steroidal anti-inflammatory drugs prescribed from the emergency department- A propensity matched analysis. Pain 2016.
Xie H, Liberzon I, Cotton AS, Elhai JD, Wall JT, Tamburrino MB, Brickman KR, Ferguson EJ, McLean SA, Wang X. Preliminary Study of Acute Changes in Emotion Processing in Trauma Survivors with PTSD Symptoms. PLOS ONE 2016.
Platts-Mills TF, Nicholson RJ, Richmond NL, Patel KV, Simonsick EM, Domeier RM, Swor RA, Hendry PL, Peak DA, Rathlev NK, Jones JS, Lee DC, Weaver MA, Keefe FJ, McLean SA. Restricted Activity and Persistent Pain following Motor Vehicle Collision among Older Adults: a Multicenter Prospective Cohort Study. BMC Geriatrics 2016.
Feinberg RK, Hu J, Weaver MA, Fillingim RB, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Liberzon I, McLean SA. Stress-Related Psychological Symptoms Contribute to Axial Pain Persistence after Motor Vehicle Collision: Path Analysis Results from A Prospective Longitudinal Study. Pain 2016.
Mauck MC, Villard MA, Liu AY, Jones S, Hwang J, Williams F, Shupp J, Karlnoski R, Smith D, Bien M, Jia E, Cairns B, Ji RR, McLean SA. Association between pain and itch symptom severity after major thermal burn injury increases over time. Presented at the Annual Meeting of the American Pain Society, Austin, TX 2016 (abstract).
Keku A, Battles S, Liu A, Soward A, D?Anza T, Bell K, Galloway L, Nouhan P, Groat J, Gieger-Sedgwick A, Ho J, Jarvis K, McLean SA. Design, Implementation, and Initial Results from the Women?s Health Study. Presented at the Annual Meeting of the American Pain Society, Austin, TX2016 (abstract).
Wang X, Xie H, Brickman KR, Bazerbashi MF, Tamburrino MB, McLean SA, Liberzon I. Early changes in cortical emotion processing circuits after mild traumatic brain injury following motor vehicle collision. Presented at the 2016 Military Health System Research Symposium 2016 (abstract).
Liu AY, Wang H, Velilla M, Pearson C, Lewandowski C, Hendry PL, Damiron K, Domeier RM, Kaushik S, Feldman JA, Jones JS, McLean SA. Previous burden of adverse life events is associated with increased acute pain in African Americans experiencing motor vehicle collision. Presented at the Annual Meeting of the American Pain Society, Austin, TX 2016 (abstract).
Villard MA, Mauck M, Liu AY, Jones S, Hwang J, Williams F, Shupp J, Karlnoski R, Smith D, Doshi N, Jallah D, Cairns B, McLean SA. PTSD influences pain and itch symptoms overtime following MThBI. Presented at the Annual Meeting of the American Pain Society, Austin, TX 2016 (abstract).
Linnstaedt SD, Wu A, Zimny E, Lewandowski C, Hendry PL, Damiron K, Pearson C, Velilla MA, Jones J, Swor R, Domeier R, McLean SA. Sex-dependent expression of microRNA-19b predicts chronic widespread pain and posttraumatic stress disorder development following trauma exposure. Presented at the Annual Meeting of the American Pain Society, Austin, TX 2016 (abstract).
Auvergne L, Bortsov AV, Ulirsch JC, Peak DA, Jones JS, Swor RA, Domeier RM, Lee DC, Rathlev NK, Hendry PL, McLean SA. Association of epidemiologic factors and genetic variants influencing HPA axis function with Post-Concussive Symptoms? after minor motor vehicle collision. Psychosomatic Medicine 2015.
Hu J, Bortsov AV, Ballina LE, Orrey DC, Swor RA, Peak D, Jones J, Rathlev N, Lee DC, Domeier R, Hendry P, McLean SA. Chronic widespread pain after motor vehicle collision typically occurs via immediate development and non-recovery: results of an emergency department-based cohort study. Pain 2015.
Linnstaedt SD, Bortsov AV, Soward AC, Swor R, Peak D, Jones J, Rathlev N, Lee DC, Domeier R, Hendry P, McLean SA. CRHBP polymorphisms predict chronic pain development following motor vehicle collision. Pain 2015.
Linnstaedt SD, Walker MG, Parker JS, Yeh E, Sons RL, Zimny E, Lewandowski C, Hendry PL, Damiron K, Pearson C, Velilla MA, O?Neil BJ, Jones JS, Swor RA, Domeier R, Hammond S, McLean SA. microRNA circulating in the early aftermath of motor vehicle collision predict persistent pain development and suggest a role for microRNA in sex-specific pain differences. Mol Pain 2015; 11.
Meloto CB, Bortsov AV, Bair E, Helgeson ES, Ostrom C, Smith SB, Dubner R, Slade GD, Fillingim RB, Greenspan JD, Ohrbach R, Maixner W, McLean SA, Luda Diatchenko. Modification of COMT-dependent pain sensitivity by psychological stress and sex. PAIN 2015.
Linnstaedt SD, Hu J, Bortsov AV, Soward AC, Swor RA, Jones JS, Lee DC, Peak DA, Domeier RM, Rathlev NK, Hendry PL, McLean SA. ?-Opioid Receptor Gene A118G variants and persistent pain symptoms among men and women experiencing motor vehicle collision. J Pain 2015; 6: 637-644.
Platts-Mills TF, Flannigan SA, Bortsov AV, Smith S, Domeier RM, Swor RA, Hendry PL, Peak DA, Rathlev NK, Jones JS, Lee DC, Keefe FJ, Sloane PD, McLean SA. Persistent pain among older adults discharged home from the emergency department after motor vehicle crash: a prospective study. Ann Emerg Med 2015.
Nyland JE, McLean SA and Loyd DL. Prior stress exposure increases pain behaviors in a rat model of full thickness thermal injury. BURNS 2015.
Walton DM, Elliott J, Lee J, Loh E, MacDermid J, Schabrun S, Siqueira WL, Corneil BD, Birmingham T, Brown A, Cooper L, Dickey JP, Dixon SJ, Fraser D, Gati J, Gloor G, Good G, Holdsworth D, McLean SA, Millard W, Miller J, Sadi J, Seguin C, Seminowicz DA, Shoemaker JK, Siegmund G, Vertseegh T, Wideman TH. Research priorities in the field of post-traumatic pain and disability: results of an interdisciplinary consensus-generating workshop. Pain Research & Management 2015.
Halawa OI, Al-Diri I, McLean SA and Darnall BD. When I’m in pain, I feel god is testing me: differences in Middle Eastern and US cancer pain experiences. J Pal Med 2015.
Nyland JE, Mclean SA and Averitt DL. Combined serotonin and norepinephrine reuptake inhibition reduces the effects of stress on post-injury pain behaviors in a rat model of burn injury, Presented at the Annual Meeting of the American Pain Society, Palm Springs, CA. J Pain 2015; 16 (abstract).
Liu AY, Hu J, Platts-Mills TF, Lateef B, Qadri YJ, Wang HE, Velilla MA, Pearson C, Zimny E, Lewandowski C, Hendry PL, Damiron K, Domeier RM, Kaushik S, Feldman JA, Jones JS, Villard MA, McLean SA. Education status is not associated with opioid medication receipt among African American emergency department patients with acute pain. Presented at the Annual Meeting of the American Pain Society, Palm Springs, CA, J Pain 2015; 16 (abstract).
Nicholson RJ, Hunold KM, Weaver MA, Lytle LA, Keefe FJ, McLean SA, Platts-Mills TF. Effect of Reduced Physical Activity on the Development of Persistent Pain After Motor Vehicle Collision in Older Adults: a Propensity Score-Matched Analysis. Presented at the Annual Meeting of the Society of Academic Emergency Medicine 2015 (abstract).
Hu J, Bollen KA, Lane ST, Bortsov AV, Peak DA, Jones JS, Swor RA, Domeier RM, Lee DC, Rathlev NK, Hendry PL, McLean SA. Evaluation of the influence of stress-induced pain vulnerability and sociodemographic characteristics on acute pain after a motor vehicle collision using structural equation modeling. Presented at American Pain Society Meeting ,Palm Springs,CA, JPain 2015; 16 (abstract).
Hu J, Bollen KA, Lane ST, Bortsov AV, Peak DA, Jones JS, Swor RA, Domeier RM, Lee DC, Rathlev NK, Hendry PL, McLean SA. Evaluation of the influence of stress-induced pain vulnerability and sociodemographic characteristics on acute pain after a motor vehicle collision using structural equation modeling. Presented at American Pain Society Meeting ,Palm Springs,CA, J Pain 2015; 16 (abstract).
Villard MA, Beaudoin FL, Hu J, Orrey D, Peak DA, Jones JS, Swor RA, Domeier RM, Lee DC, Rathlev NK, Hendry PL, McLean SA. Few individuals at high risk of persistent musculoskeletal pain after motor vehicle collision receive early psychological or physiotherapy intervention. Presented at the Annual Meeting of the American Pain Society, Palm Springs, CA, J Pain 2015; 16 (abstract).
Linnstaedt SD, Riker KD, Nyland JE, Zimny E, Lewandowski C, Hendry PL, Damiron K, Pearson C, Velilla MA, Jones J, Swor R, Domeier R, McLean SA. microRNA 320a is a potential mediator of chronic widespread hyperalgesia development after stress exposure. Presented at the Annual Meeting of the American Pain Society, Palm Springs, CA 2015; 46 (abstract).
Linnstaedt SD, Yeh E, Walker MG, Sons RL, Zimny E, Lewandowski C, Hendry PL, Damiron K, Pearson C, Velilla MA, Jones J, Swor R, Domeier R, McLean SA. MicroRNA in whole blood as predictors of severe axial pain development following motor vehicle collision trauma. Presented at the Annual Meeting of the American Society for Anesthesiology, San Diego, CA 2015 (abstract).
Lateef B, Liu AY, Hu J, MO Martel, RR Edwards, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, McLean SA. Pain Catastrophizing as a Predictor of Opioid Administration in Patients Presenting to the Emergency Department (ED) After Motor Vehicle Collision (MVC) 1(1). Presented at the Annual Meeting of the American Pain Society, Palm Springs, CA 2015 (abstract).
Mauck MC, Liu AY, Bortsov AV, Jones S, Hwang J, Williams FN, Shupp JW, Karlnoski T, Smith DJ, Krishnan A, Wesp B, Gellatly M, Cairns B, McLean SA. Predictors of pain severity after major thermal burn injury vary according to phase of burn wound healing. Presented at the Annual Meeting of the American Pain Society, Palm Springs, CA, May 2015, J Pain 2015; 16 (abstract).
Beaudoin FL, Gutman R, Peak DA, Jones JS, Swor RA, Domeier RM, Lee DC, Rathlev NK, Hendry PL, McLean SA. Treatment effects of opioids versus NSAIDs prescribed from the emergency department following motor vehicle crash: the impact on pain outcomes at 6 weeks. Presented at the Annual Meeting of the American Pain Society, Palm Springs, CA, J Pain 2015; 16 (abstract).
Bortsov AV, Velilla MA, Damiron K, Pearson C Jones JS, Hendry PL, Kurz MC, McLean SA. Vitamin D deficiency is associated with worse overall pain outcomes over time among African Americans experiencing motor vehicle collision. Presented at the Annual Meeting of the American Pain Society, Palm Springs, CA, J Pain 2015; 16 (abstract).
Bortsov AV, Diatchenko L and McLean SA. COMT haplotype interactions predict pain intensity and interference 6 weeks after motor vehicle collision. Neuromolecular Med 2014; 16(1): 83-93.
Lewis GC, Platts-Mills TF, Swor R, Peak D, Jones J, Rathlev N, Lee D, Domeier R, Hendry P, McLean SA. Incidence and Predictors of Acute Psychological Distress and Dissociation after Motor Vehicle Collision: a Cross-Sectional Study. J Trauma Dissociation 2014; 15(5): 527-47.
Lewis GC, Platts-Mills TF, Swor R, Peak D, Jones J, Rathlev N, Lee D, Domeier R, Hendry P, McLean SA. Incidence and Predictors of Acute Psychological Distress and Dissociation after Motor Vehicle Collision: a Cross-Sectional Study.. Journal of Trauma & Dissociation 2014.
McLean SA, Ulirsch JC, Slade GD, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Bortsov AV, Blair E. Incidence and Predictors of Neck and Widespread Pain after Motor Vehical Collision among US Litigants and Non-Litigants.. Pain 2014; 155(2): 309-321.
McLean SA, Ulirsch JC, Slade GD, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Bortsov AV, Bair E. Incidence and Predictors of Neck and Widespread Pain after Motor Vehicle Collision among US Litigants and Non-Litigants. Pain 2014; 155(2): 309-321.
Ulirsch JC, Ballina LE, Soward AC, Rossi C, Hauda WE, Holbrook D, Wheeler R, Foley KA, Batts J, Collette R, Goodman E, McLean SA. Pain and Somatic Symptoms are Sequelae of Sexual Assault: Results of a Prospective Longitudinal Study. Eur J Pain 2014; 18(4): 559-66.
Ulirsch JC, Ballina LE, Soward AC, Rossi C, Hauda WE, Holbrook D, Wheeler R, Foley KA, Batts J, Collette R, Goodman E, McLean SA. Pain and Somatic Symptoms are Sequelae of Sexual Assault: Results of a Prospective Longitudinal Study. Eur J Pain 2014; 18(4): 559-566.
Bortsov AV, Platts-Mills TF, Peak DA, Jones JS, Swor RA, Domeier RM, Lee DC, Rathlev NK, Hendry PL, Fillingim RB, McLean SA. Pain Location and Duration Impact Life Function Interference During the Year Following Motor Vehicle Collision. Pain 2014; 155(9): 1836-45.
Lubomirsky B, Wang X, Hong X, Smirnoff JB, Biehn TJ, Contractor AA, Elhai JD, Sutu C, Brickman KR, Liberzon I, McLean SA, Tamburrino, MB. Preliminary study on the relationship between visitation in the emergency department and posttraumatic mental health. Soc Work Ment Health2014; 12: 69-80.
Orrey DC, Halawa OI, Bortsov AV, Shupp JW, Jones SW, Haith LR, Hoskins JM, Jordan MH, Bangdiwala S, Roane BM, Platts-Mills TF, Holmes JH, Hwang J, Cairns BA, McLean SA. Results of a pilot multi-centered genotype-based randomized placebo-controlled trial of propranolol to reduce pain after major thermal burn injury.. Clinical Journal of Pain 2014.
Liu AY, Bermudez AL, Hu J, Jones S, Hwang J, Smith JE, Ballina LE, Patel A, Tran T, Karlnoski T, Smith DJ, Cairns B, McLean SA. African Americans Are at Increased Risk of Developing Chronic Pain and Itch at the Site of Tissue Autograft Following Major Thermal Burn Injury. Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
Linnstaedt SD, Walker MG, Parker JS, Sons RL, Velilla MA, Pearson C, O?Neil BJ, Zimny E, Lewandowski C, Damiron K, Hendry PL, Barnes S, Rosenberg M, Hammond SM, McLean SA. Circulating microRNA evaluated in the early aftermath of motor vehicle collision predict widespread pain development in African Americans and provide potential pathogenic insights: results of a preliminary analysis. Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
Bortsov AV, Diatchenko L and McLean SA. COMT haplotypes predict pain intensity and interference 6 weeks after motor vehicle collision. Neuromolecular Med 2014; 16(1): 83-93 (abstract).
Bortsov AV, Miller WC, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, McLean SA. Derivation of an emergency department-based clinical prediction tool to identify individuals at increased risk of chronic musculoskeletal pain development after motor vehicle collision . Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
Hu J, Bortsov AV, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Platts-Mills TF, Linnstaedt SD, McLean SA. Most widespread pain present 1 year after motor vehicle collision (MVC) begins in the early aftermath of the MVC: results of a multicenter prospective cohort study . Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
Duval ER, Wang X, Cotton AS, Xie H, Ramanujam V, Ho S, Brickman KR, Tamburrino MB, McLean SA, Liberzon I. Neural Mechanisms underlying Emotion Modulation during Recovery from Acute Stress . Presented at the American College of Neuropsychopharmacology annual meeting, Phoenix, AZ, Neuropsychopharmacology 2014; 39 (abstract).
Nichols J, Hu J, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Liberzon I, McLean SA. Not so great expectations: characteristics associated with negative expectations of physical and emotional recovery in the hours after motor vehicle collision . Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
Bermudez AL, Hu J, Bortsov AV, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Linnstaedt SD, McLean SA. Obesity increases the risk of persistent moderate or severe neck pain 6 months after motor vehicle collision. Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
Platts-Mills TF, Pereira G, Isenberg E, Weaver M, Swor RA, Jones JS, Lee DC, Peak DA, Domeier RM, Rathlev NK, Hendry PL, McLean SA. Older adults with persistent musculoskeletal pain after motor vehicle collision are at increased risk of functional decline: a prospective longitudinal study. Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
Feinberg RK, Weaver MA, Liberzon I, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, McLean SA. Stress-Related Psychological Symptoms Contribute to Neck Pain Persistence after Motor Vehicle Collision: Path Analysis Results from A Prospective Longitudinal Study . Presented at American Pain Society Meeting, Tampa, FL, J Pain 2014; 15 (abstract).
Xie H, Wall J, Liberzon I, Tamburrino M, Cotton A, Custer A, McLean SA, Brickman K, Bauer W, Wang X. Subacute cortical thickness changes after mild traumatic brain injury. Selected for presentation at the Annual Meeting of the Society of Biological Psychiatry, New York, NY, Biological Psychiatry 2014; 75 (abstract).
Linnstaedt SD , Walker MG, Bortsov AV, Swor RA, Jones JS, Lee DC, Peak DA, Domeier RM, Rathlev NK, McLean SA. The ADRA2A genetic variant rs3750635 influences extent and severity of acute pain after motor vehicle collision and may do so by regulating microRNA function. Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
Bortsov AV, Swift-Scanlan T, Diatchenko L, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, McLean SA. Variable DNA methylation in genes involved in immune response is a potential predictor of chronic widespread pain after motor vehicle collision .Presented at the Annual Meeting of the American Pain Society, Tampa, FL, J Pain 2014; 15 (abstract).
McLean SA. The Scientific Journey to Predicting and Preventing Post-Operative Pain: Recalling Dr. Wall’s stories along the way.. Anesthesiology 2013; 119(6): 1244-1246.
Bortsov AV, Platts-Mills TF, Peak DA, Jones JS, Swor RA, Domeier RM, Lee DC, Rathlev NK, Hendry PL, Fillingim RB, McLean SA. Pain Distribution and Predictors of Widespread Pain in the Immediate Aftermath of Motor Vehicle Collision. European Journal of Pain 2013; 17(8): 1243-1251.
Bortsov AV, Smith JE, Diatchenko L, Soward AC, Ulirsch JC, Rossi C, Swor RA, Hauda WE, Peak DA, Jones JS, Holbrook D, Rathlev NK, Foley KA, Lee DC, Collette R, Domeier RM, Hendry PL, McLean SA. Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure. Pain 2013; 154(8): 1419-1426.
Lubomirsky B, Wang X, Hong X, Smirnoff JB, Biehn TJ, Contractor AA, Elhai JD, Sutu C, Brickman KR, Liberzon I, McLean SA, Tamburrino MB. Preliminary study on the relationship between visitation in the emergency department and posttraumatic mental health. Social Work in Mental Health 2013; 12: 69-80.
Isaacs CG, Kistler C, Hunold KM, Pereira GF, Buchbinder M, Weaver MA, McLean SA, Platts-Mills TF. Shared Decision-Making in the Selection of Outpatient Analgesics for Older Individuals in the Emergency Department. J Am Geriatr Society 2013; 61(5): 793-798.
Hunold KM, Esserman DA, Isaacs CG, Dickey RM, Pereira GF, Fillingim RB, Sloane PD, McLean SA, Platts-Mills TF. Side Effects from Oral Opioids in Older Adults During the First Week of Treatment for Acute Musculoskeletal Pain. Academic Emergency Medicine 2013; 20(9): 872-879.
Halpern CT, Tucker CM, Bengtson A, Kupper LL, McLean SA, Martin SL. Somatic Symptoms Among US Adolescent Females: Associations with Sexual and Physical Violence Exposure. Maternal and Child Health Journal 2013; 17(10): 1951-1960.
Ballina LE, Ulirsch JC, Soward AC, Rossi C, Rotolo S, Linnstaedt SD, Heafner T, Foley KA, Batts J, Collette R, Holbrook D, Zelman S, McLean SA. u-Opioid Receptor Gene A118G Polymorphism Predicts Pain Recovery after Sexual Assault. Journal of Pain 2013; 14(2): 165-171.
Lee DC, Peak DA, Jones JS, Domeier RM, Hendry PL, Rathlev NK, Swor RA, McLean SA. Variations in institutional review board reviews of a multi-center, Emergency Department (ED)-based genetic research protocol. Am J Emerg Med 2013; 31(6): 967-969.
Platts-Mills TF, Matthews S, Pereira G, Fillingim R, Swor R, Jones J, Lee D, Peak D, Domeier R, Rathlev N, Hendry P, McLean S. Age-related differences in recovery from pain due to motor vehicle collision: a prospective longitudinal study. Journal of Pain 2013; 14(4): S13 (abstract).
Linnstaedt S, Bortsov A, Swor R, Jones J, Lee D, Peak D, Domeier R, Rathlev N, Hendry P, McLean S. Among women with substantial peritraumatic distress after minor motor vehicle collision (MVC), the presence of one or more G alleles at OPRM1 A118G is protective against developing persistent moderate or severe pain. Journal of Pain 2013; 14(4): S42 (abstract).
Verma N, Platts-Mills TF, Hunold K, Swor R, Peak D, Lee D, Jones J, Rathlev N, Domeier R, Hendry P, McLean S. Initial neuropathic pain symptoms predict musculoskeletal pain severity six weeks after MVC. Journal of Pain 2013; 14(4): S19 (abstract).
Orrey DC, Ulirsch J, Linnstaedt S, Swor R, Peak D, Jones J, Rathlev N, Lee D, Domeier R, Hendry P, McLean S. Interactions between gender and other risk factors are associated with persistent neck pain after motor vehicle collision. Journal of Pain 2013; 14(4): S17 (abstract).
Ulirsch J, Bortsov A, Soward A, Swor R, Peak D, Jones J, Rathlev N, Lee D, Domeier R, Hendry P, McLean S. No man is an island: living in a more disadvantaged neighborhood increases the likelihood of developing persistent moderate or severe neck pain 6 weeks after motor vehicle collision. Journal of Pain 2013; 14(4): S101 (abstract).
Soward A, Ulirsch J, Bair E, Slade G, Swor R, Peak D, Jones J, Rathlev N, Lee D, Domeier R, Hendry P, McLean S. Risk factors for persistent pain after motor vehicle collision differ between litigants and non-litigants. Journal of Pain 2013; 14(4): S29 (abstract).
Refereed Unpublished Presentations
Bortsov AV, Linnstaedt SD, Swor RA, Peak DA, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Jones JS, McLean SA. Genetic variants affecting CRH-binding protein predict pain persistence after trauma exposure (Abstract Presentation). Given at: American Society of Anesthesiologists Annual Conference, San Francisco, CA, 10/12/2014 – 10/16/2014.
Xie H, Wall J, Liberzon I, Tamburrino M, Cotton A, Custer A, McLean, SA, Brickman K, Bauer W, Wang X. Subacute cortical thickness changes after mild traumatic brain injury (Abstract Presentation). Given at: Annual Meeting of the Society of Biological Psychiatry, New York, NY, 05/08/2014 – 5/10/2014.
Liu AY, Bermudez AL, Hu J, Jones S, Hwang J, Smith JE, Ballina LE, Patel A, Tran T, Karlnoski T, Smith DJ, Cairns B, McLean SA. African Americans Are at Increased Risk of Developing Chronic Pain and Itch at the Site of Tissue Autograph Following Major Thermal Burn Injury (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Linnstaedt SD, Walker MG, Parker JS, Sons RL, Velilla MA, Pearson C, O’Neil BJ, Zimny E, Lewandowski C, Damiron K, Hendry PL, Barnes S, Rosenberg M, Hammond SM, McLean SA. Circulation microRNA evaluated in the early aftermath of motor vehicle collision predict widespread pain development in African Americans and provide potential pathogenic insights: results of a preliminary analysis (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Bortsov AV, Miller WC, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, McLean SA. Derivation of an emergency department-based clinical prediction tool to identify individuals at increased risk of chronic musculoskeletal pain development after motor vehicle collision (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Hu J, Bortsov AV, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Platts-Mills TF, Linnstaedt SD, McLean SA. Most widespread pain present 1 year after motor vehicle collision (MVC) begins in the early aftermath of the MVC: results of a multicenter prospective cohort study (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Nichols J, Hu J, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Liberzon I, McLean SA. Not so great expectations: characteristics associated with negative expectations of physical and emotional recovery in the hours after motor vehicle collision (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Bermudez AL, Hu J, Bortsov AV, Soward AC, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, Linnstaedt SD, McLean SA. Obesity increases the risk of persistent moderate or severe neck pain 6 months after motor vehicle collision (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Platts-Mills TF, Pereira G, Isenberg E, Weaver M, Swor RA, Jones JS, Lee DC, Peak DA, Domeier RM, Rathlev NK, Hendry PL, McLean SA. Older adults with persistent musculosketal pain after motor vehicle collision are at increased risk of functional decline: a prospective longitudinal study (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Linnstaedt SD, Walker MG, Bortsov AV, Swor RA, Jones JS, Lee DC, Peak DA, Domeier RM, Rathlev NK, McLean SA. The ADRA2A genetic variant rs3750635 influences extent and severity of acute pain after motor vehicle collision and may do so by regulating microRNA function (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Bortsov AV, Swift-Scanlan T, Diatchenko L, Swor RA, Peak DA, Jones JS, Rathlev NK, Lee DC, Domeier RM, Hendry PL, McLean SA. Variable DNA methylation in genes involved in immune response is a potential predictor of chronic widespread pain after motor vehicle collision (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, Tampa, FL, 04/30/2014 – 5/3/2014.
Adasme RA, Platts-Mills TF, Fillingim R, Swor R, Jones J, Lee D, Peak D, Domeier R, Rathlev N, Hendry P, McLean S. Fear of movement in the early aftermath of a motor vehicle collision in an independent predictor of pain interference at six weeks (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, New Orleans, LA, 05/08/2013 – 5/11/2013.
Murray CT, Ulirsch J, Soward A, Rossi C, Rotolo S, Wheeler R, Foley K, Batts J, Collette R, Holbrook D, Goodman E, Csontos E, McLean S. Most sexual assault survivors with new moderate or severe pain do not receive medical care in the initial six weeks after sexual assault (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, New Orleans, LA, 05/08/2013 – 5/11/2013.
Ulirsch J, Bortsov A, Soward A, Swor R, Peak D, Jones J, Rathlev N, Lee D, Domeier R, Hendry P, McLean SA. No man is an island: living in a more disadvantaged neighborhood increases the likelihood of developing persistent moderate or severe neck pain 6 weeks after motor vehicle collision (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, New Orleans, LA, 05/08/2013 – 5/11/2013.
Ballina L, Ulirsch J, Nielson C, Adasme RA, Thom N, Pauley C, Jones S, Hwang J, Cairns B, McLean SA. Pain catastrophizing influences pain and itch symptoms within 24 hours of skin autograph (Abstract Presentation). Given at: Annual Meeting of the American Pain Society, New Orleans, LA, 05/08/2013 – 5/11/2013.
Un-Refereed Unpublished Presentations
McLean. Neurobiologic Mechanisms of Whiplash Pathogenesis (Lecture). Given at: Symposium Speaker, 12th Research Symposium of the International Association for the Study of Pain, Aarhus, Denmark, 03/21/2014 – 3/23/2014.
McLean SA. When the Pain Doesn’t End: Research into the Transition from Acute to Chronic Pain (Lecture). Given at: The North and South Carolina Society of Anesthesiologists Annual Meeting, Asheville, NC, 09/07/2013.
McLean SA. Liar, Wimp, Drug Seeker? Understanding Pain Variability in our Patients, in the ED (Lecture). Given at: Harvard Affiliated Emergency Medicine Residency Program, Massachusetts General Hospital, Boston, MA, 06/2013.