Postdoctoral Fellowship<\/strong>: RNA Biology, Duke University Medical Center (2012)<\/span> <\/p>\n I am always most proud of the accomplishments of my trainees because it means that I\u2019ve instilled in them an enthusiasm for research and have taught them a thing or two along the way.<\/span>\u00a0<\/span><\/p>\n My lab is interested in understanding mechanisms driving the development of chronic musculoskeletal pain following traumatic stress exposures with the goal of identifying novel therapeutic strategies that reduce the burden of chronic pain suffering across the globe. To accomplish this goal, we use translational research methods including the analysis of biological data from longitudinal observational human cohort studies and behavioral, molecular, and cell culture models of the human pain condition. We are particularly interested in the role that the physiological stress system plays in chronic pain development and are also interested in understanding why women are far more vulnerable to chronic pain than men. Overall, my lab\u2019s goal is to develop at least one novel, non-addictive, therapeutic strategy that is effective at reducing chronic pain in the millions of trauma survivors in need each year.<\/span>\u00a0<\/span><\/p>\n 2024-2029: Sex-Dependent microRNA-mediated Pathways to Chronic Musculoskeletal Pain Following Trauma<\/em> 2023-2025: Repurposing Estrogen-Containing Emergency Contraceptives for the Prevention of Chronic Pain Following Sexual Assault<\/em><\/span>\u00a0<\/em> 2022-2027: Discovering Diagnostics, Subtypes, and Natural History of Traumatic Brain Injury (TBI) vs non-TBI Recovery to Gain Military Advantage (the DISENTANGLE study)<\/em><\/span>\u00a0<\/em> 2022-2023: Diversity Supplement to FKBP51 Antagonism to Prevent Chronic Pain: Optimizing Efficacy and Evaluating Safety and Mechanisms.\u00a0<\/em><\/span> 2020-2025: FKBP51 Antagonism to Prevent Chronic Pain: Optimizing Efficacy and Evaluating Safety and Mechanisms<\/em><\/span> 2020-2023: FKBP51 Inhibition to Prevent Chronic Pain Following Traumatic Stress 2016-2022: Longitudinal Assessment of Post-Traumatic Syndromes<\/em><\/span>\u00a0<\/em> 2018-2022: Key Molecular Mechanisms of Chronic Pain Vulnerability in Women Experiencing MVC.\u00a0<\/em> 2014-2019: Supplement to \u201cInfluence of PTSD Symptoms on Chronic Pain Development after Sexual Assault<\/em>\u201d<\/span> 2015-2016: <\/span>MicroRNA Mechanisms Mediating Chronic Pain Development After Motor Vehicle Trauma<\/em> 2014-2015: MicroRNA as Mediators of Chronic Pain Development Following Motor Vehicle Collision<\/em><\/span> 2023-2024 <\/span>Yang Family Biomedical Scholar Outside of the lab, I love photography, travel, cooking, baking, spending time with friends and most of all, spending time with family (which includes four kids and numerous pets!)<\/span>\u00a0<\/span><\/p>\n Visit the Linnstaedt Lab<\/a>\n","protected":false},"excerpt":{"rendered":"
\nGraduate School<\/strong>: Ph.D. in Molecular and Cell Biology, Georgetown University (2008)<\/span>
\n<\/span>Undergraduate<\/strong>: B.S., Virginia Tech (2003)<\/span><\/p>\nWhat was your greatest recent accomplishment?\u00a0<\/strong><\/h4>\n
What is your lab\u2019s research focus?<\/strong>\u00a0<\/span><\/h4>\n
What grants have you received?<\/strong>\u00a0<\/span><\/h4>\n
\n<\/span>NIAMS R01AR081454
\n<\/span><\/a>PI: S. Linnstaedt<\/span>\u00a0<\/span><\/p>\n
\n<\/span>Cures Within Reach<\/span>
\n<\/span>PI: S. Linnstaedt<\/span>\u00a0<\/span><\/p>\n
\n<\/span>W81XWH22C0122<\/span>
\n<\/span>PI: S. McLean, Co-I: S. Linnstaedt<\/span>\u00a0<\/span><\/p>\n
\n<\/em>NINDS – R01NS118563-01A1S1<\/a>
\n<\/span>PI: Linnstaedt<\/span>\u00a0<\/span><\/p>\n
\n<\/span>NINDS – R01NS118563<\/a>
\n<\/span>PI: S. Linnstaedt, Co-PI: S. McLean<\/span>\u00a0<\/span><\/p>\n
\n<\/em><\/span>Rita Allen Award in Pain, Rita Allen Foundation
\n<\/span>PI: S. Linnstaedt<\/span><\/p>\n
\n<\/span>NIMH – U01MH110925<\/span>
\n<\/span>PI: S. McLean, Co-I: S. Linnstaedt<\/span>\u00a0<\/span><\/p>\n
\n<\/span>NIAMS – K01AR071504\u00a0<\/a><\/span>
\n<\/span>PI: S. Linnstaedt<\/span>\u00a0<\/span><\/p>\n
\n<\/span>Mayday Fund<\/span>
\n<\/span>PIs: S. Linnstaedt and S. McLean<\/span>\u00a0<\/span><\/p>\n
\nFuture Leaders in Pain Grant, The American Pain Society.<\/span>
\nPI: S. Linnstaedt<\/span>\u00a0<\/span><\/p>\n
\n<\/span>IBM Junior Faculty Development Award, University of North Carolina at Chapel Hill<\/span>
\n<\/span>PI: S. Linnstaedt
\n<\/span>\u00a0<\/span><\/p>\nWhat honors have you received?\u00a0<\/strong><\/h4>\n
\n2023 NIH HEAL Director\u2019s Trailblazer Award.<\/span>
\n<\/span>2020 Rita Allen Foundation Pain Scholar Award, Rita Allen Foundation.<\/span>
\n<\/span>2020 Best Poster Award from the UNC School of Medicine Center for Women\u2019s Health Research<\/span>
\n<\/span>2018 <\/span>Recognition of our work on the NIH Director’s Blog<\/span><\/a>
\n<\/span>2018 Federal Work Study Supervisor of the Year Award Nominee\u00a0<\/span>
\n<\/span>2015 Special Recognition from the Basic Science Shared Interest Group of the American Pain Society<\/span>
\n<\/span>2014 Future Leader in Pain Research Award, American Pain Society<\/span>
\n<\/span>2014 Top Abstract Award from the Pain Genetics Committee of the American Pain Society\u00a0<\/span>
\n<\/span>2011 Best Research and Oral Presentation, Center for AIDS Research Annual Retreat, Duke University<\/span>
\n<\/span>2008 Maengwyn-Davies Award, Most Outstanding PhD Thesis, Georgetown University<\/span>\u00a0<\/span><\/p>\nHobbies<\/strong><\/h4>\n