## Summary statistics for sex-chromosome association analysis of 2,822 brain imaing traits, including regional brain volumes (101), cortical thickness (63), surface area (66), DTI-AD-PC (105), DTI-FA-PC (105), DTI-MD-PC (105), DTI-MO-PC (105), DTI-RD-PC (105), DTI-mean (110), rfMRI-ICA (1777), rfMRI-G360 (90), and tfMRI-G360 (90).

For annotation of surface area, DTI and fMRI traits, please refers to Traits_annotation.xlsx

## Version
Sept. 1, 2023

## Author
Zhiwen (Owen) Jiang, owenjf@live.unc.edu

## Sample size
n = 34,000 (UKB white cohort in phase 1 to 3)

## Number of reported SNPs
289,000 NPR SNPs on the chrX, 11,000 PAR SNPs on the chrX, and 140 SNPs on the chrY.

## Association analysis was performed by plink 2.00 https://www.cog-genomics.org/plink/2.0/

## Each file contains the following columns
CHROM: chromosome
POS: physical position (GRCh 37)
ID: SNP identifier
REF: reference allele
ALT: alternative allele
A1: minor allele that was tested
TEST: method of testing (additive model)
OBS_CT: per-SNP sample size
BETA: SNP effect
SE: SNP SE
T_STAT: SNP T statistic
P: p-value
ERRCODE: indicator of errors

## Reference
Jiang, Zhiwen, et al. "The pivotal role of the X-chromosome in the genetic architecture of the human brain." medRxiv (2023): 2023-08.

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