{"id":3004,"date":"2018-09-18T13:20:28","date_gmt":"2018-09-18T17:20:28","guid":{"rendered":"https:\/\/www.med.unc.edu\/bigs2\/?page_id=3004"},"modified":"2020-10-13T19:15:11","modified_gmt":"2020-10-13T23:15:11","slug":"frats","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/bigs2\/frats\/","title":{"rendered":"FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit"},"content":{"rendered":"<div id=\"content1\">\n<div id=\"main\">\n<div id=\"right\">\n<div id=\"right_text\">\n<div class=\"box\">\n<p>FRATS, Functional Regression Analysis of DTI Tract Statistics, is a functional\u00a0regression framework, is for the analysis of multiple diffusion properties\u00a0along fiber bundle as functions in an infinite dimensional space and their\u00a0association with a set of covariates of interest, such as age, diagnostic\u00a0status and gender, in real applications. It consists of four integrated\u00a0components: the local polynomial kernel method for smoothing multiple diffusion\u00a0properties along individual fiber bundles, a functional linear model for\u00a0characterizing the association between fiber bundle diffusion properties and a\u00a0set of covariates, a global test statistic for testing hypotheses of interest,\u00a0and a resampling method for approximating the p-value of the global test\u00a0statistic. The resulting analysis pipeline can be used for understanding normal\u00a0brain development, the neural bases of neuropsychiatric disorders, and the\u00a0joint effects of environmental and genetic factors on white matter fiber\u00a0bundles.<\/p>\n<p><strong><a href=\"http:\/\/www.nitrc.org\/projects\/frats\/\">Software Download (with GUI)<\/a><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Citation<\/strong>: Zhu H, Styner M, Tang N, Liu Z, Lin W, Gilmore JH. FRATS: Functional Regression Analysis of DTI Tract Statistics. <em>IEEE Trans Med Imaging<\/em>. 2010.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"footer\">\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<p><!-- footer ends--><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>FRATS, Functional Regression Analysis of DTI Tract Statistics, is a functional\u00a0regression framework, is for the analysis of multiple diffusion properties\u00a0along fiber bundle as functions in an infinite dimensional space and their\u00a0association with a set of covariates of interest, such as age, diagnostic\u00a0status and gender, in real applications. It consists of four integrated\u00a0components: the local polynomial &hellip; <a href=\"https:\/\/www.med.unc.edu\/bigs2\/frats\/\" aria-label=\"Read more about FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit\">Read more<\/a><\/p>\n","protected":false},"author":1503,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-3004","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit - BIG-S2<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit - BIG-S2\" \/>\n<meta property=\"og:description\" content=\"FRATS, Functional Regression Analysis of DTI Tract Statistics, is a functional\u00a0regression framework, is for the analysis of multiple diffusion properties\u00a0along fiber bundle as functions in an infinite dimensional space and their\u00a0association with a set of covariates of interest, such as age, diagnostic\u00a0status and gender, in real applications. It consists of four integrated\u00a0components: the local polynomial &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/bigs2\/frats\/\" \/>\n<meta property=\"og:site_name\" content=\"BIG-S2\" \/>\n<meta property=\"article:modified_time\" content=\"2020-10-13T23:15:11+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/bigs2\/frats\/\",\"url\":\"https:\/\/www.med.unc.edu\/bigs2\/frats\/\",\"name\":\"FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit - BIG-S2\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/bigs2\/#website\"},\"datePublished\":\"2018-09-18T17:20:28+00:00\",\"dateModified\":\"2020-10-13T23:15:11+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/bigs2\/frats\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/bigs2\/frats\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/bigs2\/frats\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/bigs2\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/bigs2\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/bigs2\/\",\"name\":\"BIG-S2\",\"description\":\"Biostatistics and Imaging Genomics analysis lab - Statistics &amp; Signal\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/bigs2\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit - BIG-S2","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit - BIG-S2","og_description":"FRATS, Functional Regression Analysis of DTI Tract Statistics, is a functional\u00a0regression framework, is for the analysis of multiple diffusion properties\u00a0along fiber bundle as functions in an infinite dimensional space and their\u00a0association with a set of covariates of interest, such as age, diagnostic\u00a0status and gender, in real applications. It consists of four integrated\u00a0components: the local polynomial &hellip; Read more","og_url":"https:\/\/www.med.unc.edu\/bigs2\/frats\/","og_site_name":"BIG-S2","article_modified_time":"2020-10-13T23:15:11+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/bigs2\/frats\/","url":"https:\/\/www.med.unc.edu\/bigs2\/frats\/","name":"FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit - BIG-S2","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/bigs2\/#website"},"datePublished":"2018-09-18T17:20:28+00:00","dateModified":"2020-10-13T23:15:11+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/bigs2\/frats\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/bigs2\/frats\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/bigs2\/frats\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/bigs2\/"},{"@type":"ListItem","position":2,"name":"FRATS: Functional Regression Analysis of DTI Tract Statistics, a DTI-Statistics Toolkit"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/bigs2\/#website","url":"https:\/\/www.med.unc.edu\/bigs2\/","name":"BIG-S2","description":"Biostatistics and Imaging Genomics analysis lab - Statistics &amp; Signal","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/bigs2\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/bigs2\/wp-json\/wp\/v2\/pages\/3004","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/bigs2\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/bigs2\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/bigs2\/wp-json\/wp\/v2\/users\/1503"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/bigs2\/wp-json\/wp\/v2\/comments?post=3004"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/bigs2\/wp-json\/wp\/v2\/pages\/3004\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/bigs2\/wp-json\/wp\/v2\/media?parent=3004"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}