BCBP Seminar: Sarah Keane PhD

Sarah Keane, Ph.D., Assistant Professor, Chemistry and Biophysics

University of Michigan

Host: Qi Zhang

Title: Structural determinants of microRNA biogenesis

Research: The discovery of functional non-coding (nc) RNAs has revolutionalized our understanding of gene expression and regulation. There is a wealth recent information implicating ncRNAs as regulators of a variety of cellular and pathogenic processes. To this end, we are interested in uncovering the mechanisms and functional roles of ncRNAs in disease progression using a combination of biomolecular NMR and other biophysical and structural tools.