Seminar: Hashim Al-Hashimi (Duke)
February 4 @ 11:00 am - 12:00 pm
James B. Duke Professor of Biochemistry
Director, Duke Center for RNA Biology
Duke University School of Medicine
Host: Ron Swanstrom
“DNA Dynamics Driven Mutagenesis: How DNA Contributes to it’s Own Copying Errors”
Mutations drive evolution and cause diseases such as cancer. But what causes mutations? In this lecture, I will advance a new perspective in which the dynamics of the base pairs in the DNA double helix play an important role determining when, where, and to what extent mutations occur.