Shan Zha, M.D., Ph.D., James A Wolff Professor of Pediatrics, Pathology and Cell Biology and of Microbiology and Immunology (in the Institute for Cancer Genetics and in the Herbert Irving Comprehensive Cancer Center Department of Pathology and Cell Biology Columbia University Title: “Inhibition is not deletion in DNA damaging therapies” Host: Xian Chen
Wei Xu, Ph.D., Professor of Oncology University of Wisconsin-Madison Host: Xian Chen Title: “Targeting estrogen receptors and cofactors for precision medicine in breast cancer”
This publication is the result of collaboration with many researchers from UNC Biochemistry and Biophysics, Lineberger, University of Texas Southwestern, University of Edinburgh, Center for Epigenetics-Van Andel Institute, and Yale. First co-authors are Drs. Xijuan Liu and Jun Wang. Congratulations on your publication in Nature! Subjects: Breast cancer, Epigenetics, Gene Expression.
— January 25 (Virtual) Elizabeth Kellogg, Ph.D., Assistant Professor, Dept. of Molecular Biology & Genetics Cornell University Host: Brian Kuhlman Title: Mechanistic studies of CRISPR-associated transposons (CAST) using cryo-EM February 8 (Virtual) Peter Penzes, Ph.D., Director, Center for Autism and Neurodevelopment Northwestern University -Host: Patricia Maness Title: Synaptic biology of ankyrin February 15 … Read more
Lingjun Li, Ph.D., Professor, Pharmaceutical Sciences and Chemistry, University of Wisconsin-Madison Venue: Zoom Talk Title: Advancing Biomedical Research via Innovation in Mass Spectrometry-based Approaches Host: Xian Chen
Abstract: Protein hydroxylation affects protein stability, activity, and interactome, therefore contributing to various diseases including cancers. However, the transiency of the hydroxylation reaction hinders the identification of hydroxylase substrates.
The second edition of “On the Record with LP.”
This paper describes a ground-breaking multi-omics technology to discover drivers of proliferative and invasive breast tumors.
Thesis title: Secretotranscriptomics: A Novel Approach to the Discovery of Liquid Biopsy Biomarkers for Breast Cancer Prognosis Seminar is based upon the doctoral dissertation of Astor Ankney under the direction of Dr. Xian Chen ABSTRACT Presently, a 50-gene expression model (PAM50) serves as a breast cancer subtype classifier that is insufficient to distinguish, within each … Read more
BING ZHANG, PHD ǀ Baylor College of Medicine Host: Xian Chen “Proteogenomics: A New Avenue for Cancer Research” Proteogenomics is a new research field at the interface of genomics and proteomics. In this talk, I will introduce our computational infrastructure and bioinformatics tools for cancer proteogenomic data analysis. Using proteogenomics data from the Clinical … Read more
Spring 2018 JANUARY 16 VICTORIA D’ SOUZA, PHD ǀ Harvard UniversityHost: Qi Zhang “Unraveling Viral RNA Genomes: One Segment at a time” Joint Seminar with the UNC Program in Molecular & Cellular Biophysics JANUARY, 30 UNC BIOCHEMISTRY & BIOPHYSICS GRADUATE STUDENT INVITED LECTURE BILL CLEMONS, PHD ǀ Cal Tech “Structural insights into the targeting of tail-anchored membrane … Read more
