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Adil Muneer earned his PhD under the direction of Dr. Xian Chen

December 1, 2023

Adil Muneer successfully defended his dissertation under the direction of Dr. Xian Chen on August 25th, 2023, and he has received his PhD. The title of his dissertation is “Non-canonical translation regulatory function of G9a in chronic inflammation associated diseases.”

Student Thesis defense: Adil Muneer (Xian Chen lab)

August 25, 2023

Title “Non-canonical translation regulatory function of G9a in chronic inflammation associated diseases” Join us on Monday August 28 at 1 PM in Marsico 2004. For Zoom information contact the student.

Xian Chen

June 27, 2015

Research: Systems cancer biology and immunology, cancer therapeutic response, protein-protein interaction networks (interactomes), post-translational modifications, epigenetic regulation, signal transduction, disease marker discovery.

Freezer Challenge encourages energy-saving practices

September 14, 2022

As part of a growing green-lab movement, Carolina competes with labs internationally to cut the high cost of cold storage. Xian Chen’s lab is highlighted for being one of the two labs at UNC who participated in the international challenge!

Latest Grant Awards to SOM Faculty

October 7, 2021

Xian Chen PhD and Aziz Sancar MD PhD were among those who received grants at the School of Medicine during 9/15/2021 – 9/30/2021.

Our team publishes cell proliferation research in Science Advances

January 4, 2021

CRL4DCAF1/VprBP E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development. Authors: Xiao-Ran Han, Naoya Sasaki, Sarah Jackson, Pu Wang, Zhijun Li, Matthew Smith, Ling Xie, Xian Chen, Yanping Zhang, Bill Marzluff and Yue Xiong publishes cell proliferation research in Science Advances.

Prognostic tool could identify high-risk breast cancer patients

March 1, 2018

In the journal Cell Chemical Biology, researchers led by Biochemistry and Biophysics Associate Professor and Faculty Director, Quantitative Proteomics Center for Disease Marker Discovery, Xian Chen, PhD, report on potential prognostic tool that could be used to identify high-risk patients within particular subtypes of breast cancer.

UNC team reports a novel DNA Damage-Dependent Tumor Suppressor

July 27, 2012

Life is full of choices, and even cells come to a fork in the road. They have to decide what to do about damage to their DNA: repair the damage, force the damaged cell to die, or allow the damage to transform the cell to a tumor cell. Read more on the work from the Xian Chen lab in the Department of Biochemistry & Biophysics that was published in Cell Death & Disease.