{"id":13964,"date":"2020-02-27T15:45:07","date_gmt":"2020-02-27T20:45:07","guid":{"rendered":"https:\/\/www.med.unc.edu\/biochem\/?p=13964"},"modified":"2020-05-06T15:57:35","modified_gmt":"2020-05-06T19:57:35","slug":"congrats-qi-zhang-and-saskia-neher-on-teams-receiving-emerging-challenges-grants","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/biochem\/news\/congrats-qi-zhang-and-saskia-neher-on-teams-receiving-emerging-challenges-grants\/","title":{"rendered":"Congrats Qi Zhang and Saskia Neher on Teams Receiving Emerging Challenges Grants"},"content":{"rendered":"

The UNC School of Medicine awarded the 2019 Emerging Challenges in Biomedical Research Awards to five teams conducting basic science research in the fields of machine-learning, flaviviruses, vaping, and LPL trafficking<\/span><\/p>\n

The School of Medicine Office of Research provided five teams up to $50,000 in funding as part of the 2019 Emerging Challenges in Biomedical Research (ECBR) Mechanism. ECBR awards are meant to provide pilot funding for early stage projects relevant to NIH priorities, and the Fall 2019 round was to recognize the importance and impact of fundamental research by supporting interdisciplinary, technology-focused, basic science research that can lead to new discoveries or technologies. Furthermore, basic science research related to vaping was considered high-priority due to the current vaping epidemic and reports on vaping related illnesses and deaths.<\/p>\n

\u201cBasic science research leads to the mechanistic understanding of living systems and creates foundational knowledge necessary to develop new drugs, treatments, and new technologies\u201d said Blossom Damania, PhD, UNC School of Medicine Vice Dean for Research. \u201cThe importance of basic science and discovery research cannot be over-emphasized.\u00a0 We are very proud of the outstanding basic science research done here at UNC and were pleased to receive a record number of applications from a spectrum of topics and disciplines\u201d. With five awards, the School of Medicine Office of Research is supporting the largest number of projects in a single ECBR round.<\/p>\n

\"Qi
Qi Zhang, PhD<\/figcaption><\/figure>\n

One awarded team consists of\u00a0Qi Zhang, PhD<\/a>, Associate Professor in the Department of Biochemistry and Biophysics and\u00a0Helen Lazear, PhD<\/a>, Assistant Professor in the Department of Microbiology and Immunology, and will develop a novel technique to characterize xrRNAs from flaviviruses, vector-borne pathogens that cause disease, to better understand the virus-host interactions that dictate flavivirus vector specificity.<\/p>\n

\"Saskia

Saskia Neher, PhD<\/figcaption><\/figure>\n

Saskia Neher, PhD<\/a>, Associate Professor in the Department of Biochemistry and Biophysics and\u00a0Stephanie Gupton, PhD<\/a>, Associate Professor in the Department of Cell Biology and Physiology will use their funding to determine how insulin mobilizes LPL in secretory vesicles and use this information to better understand the dyslipidemia and increased cardiovascular disease risk seen in diabetic patients.<\/p>\n

Melissa Herman, PhD<\/a>, Assistant Professor in the Department of Pharmacology and\u00a0Robert Tarran, PhD<\/a>, Professor in the Department of Cell Biology and Physiology will investigate the role of vitamin E acetate on pulmonary inflammation and neural immune activation to illuminate new information about the pathology of electronic-cigarette vaping-associated lung injury (EVALI).<\/p>\n

The second vaping-related proposal is led by\u00a0Samir Kelada, PhD<\/a>, Associate Professor in the Department of Genetics,\u00a0Ilona Jaspers, PhD<\/a>, Professor in the Department of Pediatrics, and\u00a0Timothy Moran, MD<\/a>, PhD, Assistant Professor in the Department of Pediatrics. Together they will use the\u00a0Collaborative Cross murine resource<\/a>\u00a0to create a novel mouse model of EVALI, and characterize the genetic basis of adverse responses to e-cigarette aerosols.<\/p>\n

The fifth awarded team led by\u00a0Corbin Jones, PhD<\/a>, Professor in the Integrative Program for Biological and Genome Sciences and the Department of Biology,\u00a0Ross Boyce, MD<\/a>, Assistant Professor in the Department of Medicine, and\u00a0Dan Schrider, PhD<\/a>, Assistant Professor in the Department of Genetics will aim to use machine-learning to identify the genetic, evolutionary and ecological forces that lead to differences among mosquito vectors.<\/p>\n

\u00a0\u201cThe awarded teams not only exemplify the depth of basic science research in the School of Medicine, but also the collaborative, multidisciplinary nature of the research done here\u201d notes Damania. \u201cAll of these teams are capitalizing unique strengths of individual members to address big questions and we look forward to seeing the outcome of their endeavors\u201d.<\/p>\n

News courtesy of UNC Health and School of Medicine Newsroom<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

The UNC School of Medicine awarded the 2019 Emerging Challenges in Biomedical Research Awards to five teams conducting basic science research in the fields of machine-learning, flaviviruses, vaping, and LPL trafficking The School of Medicine Office of Research provided five teams up to $50,000 in funding as part of the 2019 Emerging Challenges in Biomedical … Read more<\/a><\/p>\n","protected":false},"author":41619,"featured_media":13965,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[10,298],"class_list":["post-13964","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news_faculty","tag-news_2020","odd"],"acf":[],"yoast_head":"\nCongrats Qi Zhang and Saskia Neher on Teams Receiving Emerging Challenges Grants | 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