{"id":19450,"date":"2021-09-22T16:10:47","date_gmt":"2021-09-22T20:10:47","guid":{"rendered":"https:\/\/www.med.unc.edu\/biochem\/?p=19450"},"modified":"2021-09-22T16:29:22","modified_gmt":"2021-09-22T20:29:22","slug":"student-seminar-series-resumed-with-presentations-by-cathy-anderson-spangler-and-gabby-budziszewski","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/biochem\/news\/student-seminar-series-resumed-with-presentations-by-cathy-anderson-spangler-and-gabby-budziszewski\/","title":{"rendered":"Student Seminar series resumed with presentations by Cathy (Anderson) Spangler and Gabby Budziszewski"},"content":{"rendered":"<figure id=\"attachment_19451\" class=\"thumbnail wp-caption alignnone\" style=\"width: 310px\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-19451 size-medium\" src=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-Anderson-Spangler-and-Gabby-Budziszewski-300x213.png\" alt=\"Cathy Anderson Spangler and Gabby Budziszewski\" width=\"300\" height=\"213\" srcset=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-Anderson-Spangler-and-Gabby-Budziszewski-300x213.png 300w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-Anderson-Spangler-and-Gabby-Budziszewski.png 438w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption class=\"caption wp-caption-text\">BCBP Graduate students in McGinty lab, Cathy Anderson Spangler and Gabby Budziszewski<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>On September 16, 2021, the Student Seminar series resumed with virtual presentations by Cathy (Anderson) Spangler and Gabby Budziszewski.<\/p>\n<h2><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-19456 size-large\" src=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-talk-1024x457.png\" alt=\"Cathy (Anderson) Spangler zoom talk\" width=\"1024\" height=\"457\" srcset=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-talk-1024x457.png 1024w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-talk-300x134.png 300w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-talk-768x343.png 768w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-talk-600x268.png 600w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-talk-560x250.png 560w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Cathy-talk.png 1211w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>Cathy (Anderson) Spangler<\/h2>\n<p>Seminar title: &#8220;Exploring the mechanistic basis of nucleosome interactions&#8221;<br \/>\nPI: Robert McGinty<br \/>\nIn this talk, Cathy discussed how we have recently used bulk and single-molecule biophysical and cellular studies to investigate how different interaction interfaces between histone methyltransferase Dot1L and the nucleosome contribute to Dot1L binding and activity in leukemia.<\/p>\n<h2><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-19457 size-large\" src=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Gabby-talk-1024x531.png\" alt=\"Gabby Budziszewski zoom talk\" width=\"1024\" height=\"531\" srcset=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Gabby-talk-1024x531.png 1024w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Gabby-talk-300x156.png 300w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Gabby-talk-768x399.png 768w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Gabby-talk-600x311.png 600w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Gabby-talk-560x291.png 560w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2021\/09\/Gabby-talk.png 1131w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>Gabby Gabby Budziszewski<\/h2>\n<p>Seminar title: &#8220;Chromatin kinase VRK1 engages the nucleosome multivalently to phosphorylate histone H3 threonine 3&#8221;<br \/>\nPI: Rob McGinty<br \/>\nIn this talk, Gabby discussed the mechanism by which VRK1 binds the nucleosome: namely, by binding both DNA linker regions as well as the histone disk face. The multivalent nature of this interaction has implications for the kinase&#8217;s ability to phosphorylate histone H3 tails, a function that is crucial to the proper segregation of chromosomes during mitosis.<\/p>\n<p>Fall 2021 and Spring 2022 BCBP Student Seminar Series talks will be held virtual via zoom.<\/p>\n<h2><a href=\"https:\/\/www.med.unc.edu\/biochem\/event\/bcbp-student-seminar-series-5\/2021-09-16\/\">Fall 2021 Student Seminars<\/a><\/h2>\n<p>Student seminars <em>for students by students<\/em> occur Third Thursday of every month at noon on 9\/16, 10\/21, and 11\/18.<\/p>\n<h2><a href=\"https:\/\/www.med.unc.edu\/biochem\/event\/bcbp-student-seminar-series-6\/2022-01-20\/\">Spring 2022 Student Seminars<\/a><\/h2>\n<p>Student seminars <em>for students by students<\/em> occur Third Thursday of every month at noon on 1\/20, 2\/17, 3\/17, 4\/21, and the Award ceremony will be held on 5\/19.<\/p>\n<h2>Award nominations<\/h2>\n<p>Students have opportunities to nominate their peers for awards that will be held on May 19. Students, please check your email from Odessa for the link to the nomination form.<\/p>\n<p>The award categories are:<\/p>\n<ul style=\"list-style-type: circle\">\n<li>Excellent presentation organization and clarity<\/li>\n<li>Excellent visual aids\/appeal<\/li>\n<li>Ability to connect with the audience<\/li>\n<li>Excellent timing\/pacing of the presentation<\/li>\n<li>Overall outstanding presentation<\/li>\n<\/ul>\n<p>Reem, Rhese, and Jeff will present Student Seminars over Zoom on October 21.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Each month BCBP students have opportunities to present their research in front of their peers. <\/p>\n","protected":false},"author":41619,"featured_media":19451,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[363,13],"class_list":["post-19450","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news_2021","tag-news_students","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Student Seminar series resumed with presentations by Cathy (Anderson) Spangler and Gabby Budziszewski | Biochemistry and Biophysics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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