{"id":25343,"date":"2023-02-09T09:57:00","date_gmt":"2023-02-09T14:57:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/biochem\/?p=25343"},"modified":"2023-02-16T14:44:31","modified_gmt":"2023-02-16T19:44:31","slug":"dr-saskia-neher-received-an-r01-grant-for-381864-from-nhlbi","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/biochem\/news\/dr-saskia-neher-received-an-r01-grant-for-381864-from-nhlbi\/","title":{"rendered":"Dr. Saskia Neher received an R01 grant for $1,527,456 from NHLBI"},"content":{"rendered":"<p><a href=\"https:\/\/www.med.unc.edu\/biochem\/directory\/neher\/\">Dr. Saskia Neher<\/a> Associate Professor of Biochemistry and Biophysics received an R01 for her project \u201cLipoprotein Lipase Through the Secretory System\u201d from the National Heart, Lung, And Blood Institute of the National Institutes of Health (NHLBI) for <span class=\"TextRun SCXW73668802 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW73668802 BCX8\">$1,527,456 <\/span><\/span>for the period of 12\/21\/2022 through 11\/30\/2026.<\/p>\n<hr \/>\n<figure id=\"attachment_11800\" class=\"thumbnail wp-caption alignright\" style=\"width: 210px\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-11800 size-medium\" src=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2019\/11\/Neher.Sakia_.2019April-200x300.jpg\" alt=\"Saskia Neher\" width=\"200\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2019\/11\/Neher.Sakia_.2019April-200x300.jpg 200w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2019\/11\/Neher.Sakia_.2019April-768x1151.jpg 768w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2019\/11\/Neher.Sakia_.2019April-683x1024.jpg 683w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2019\/11\/Neher.Sakia_.2019April-600x899.jpg 600w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><figcaption class=\"caption wp-caption-text\">Saskia Neher PhD, Associate Professor<\/figcaption><\/figure>\n<blockquote><p>PI: Dr. Saskia Neher<br \/>\nProject Title: \u201cLipoprotein Lipase Through the Secretory System\u201d<br \/>\nSponsor: National Heart, Lung, And Blood Institute of the National Institutes of Health (NHLBI)<br \/>\nAward Amount: <span class=\"TextRun SCXW73668802 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW73668802 BCX8\">$1,527,456\u00a0<\/span><\/span><span class=\"EOP SCXW73668802 BCX8\" data-ccp-props=\"{&quot;201341983&quot;:1,&quot;335559739&quot;:160,&quot;335559740&quot;:480}\">\u00a0<\/span><br \/>\nGrant Award type: R01<br \/>\nProject Dates: 12\/21\/2022 &#8211; 11\/30\/2026<\/p><\/blockquote>\n<p>The Research Project Grant (R01) is the original and historically oldest grant mechanism used by NIH. The R01 provides support for health-related research and development based on the mission of the NIH.<\/p>\n<p><span class=\"TextRun SCXW180466303 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW180466303 BCX8\">The Neher lab primarily studies proteins involved in lipid metabolism. They use structural biology, biochemistry, and microscopy to answer questions about enzyme function, inhibition, and trafficking.<\/span><span class=\"NormalTextRun SCXW180466303 BCX8\"> This new award focuses on lipoprotein lipase, the main enzyme responsible for <\/span><span class=\"NormalTextRun SCXW180466303 BCX8\">hydrolyzing triglycerides from circulating lipoproteins. It will allow the lab to better understand how lipoprotein lipase <\/span><span class=\"NormalTextRun SCXW180466303 BCX8\">moves<\/span><span class=\"NormalTextRun SCXW180466303 BCX8\"> from cells into<\/span><span class=\"NormalTextRun SCXW180466303 BCX8\"> the<\/span><span class=\"NormalTextRun SCXW180466303 BCX8\"> blood in response to insulin <\/span><span class=\"NormalTextRun SCXW180466303 BCX8\">signaling<\/span><span class=\"NormalTextRun SCXW180466303 BCX8\">.\u00a0<\/span><\/span><span class=\"EOP SCXW180466303 BCX8\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/neherlab.web.unc.edu\/research\/\">Neher lab<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Saskia Neher received an R01 from the National Heart, Lung, And Blood Institute of the National Institutes of Health for $1,527,456 for her project \u201cLipoprotein Lipase Through the Secretory System\u201d which is funded through November 30, 2026.<\/p>\n","protected":false},"author":41619,"featured_media":11800,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[10,385],"class_list":["post-25343","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news_faculty","tag-news_2023","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dr. Saskia Neher received an R01 grant for $1,527,456 from NHLBI | Biochemistry and Biophysics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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