{"id":27232,"date":"2023-08-15T12:01:38","date_gmt":"2023-08-15T16:01:38","guid":{"rendered":"https:\/\/www.med.unc.edu\/biochem\/?p=27232"},"modified":"2023-08-16T11:33:07","modified_gmt":"2023-08-16T15:33:07","slug":"zhijun-li-phd-joins-qi-zhangs-lab-as-a-research-assistant-professor","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/biochem\/news\/zhijun-li-phd-joins-qi-zhangs-lab-as-a-research-assistant-professor\/","title":{"rendered":"Zhijun Li PhD joins Qi Zhang\u2019s Lab as a Research Assistant Professor"},"content":{"rendered":"<p><strong>Meet Dr. Zhijun Li<\/strong><\/p>\n<figure id=\"attachment_27230\" class=\"thumbnail wp-caption alignright\" style=\"width: 298px\"><a href=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2023\/08\/Zhijun-Li-phd-2023-new-faculty.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-27230\" src=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2023\/08\/Zhijun-Li-phd-2023-new-faculty-288x300.jpg\" alt=\"Zhijun Li\" width=\"288\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2023\/08\/Zhijun-Li-phd-2023-new-faculty-288x300.jpg 288w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2023\/08\/Zhijun-Li-phd-2023-new-faculty-600x625.jpg 600w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2023\/08\/Zhijun-Li-phd-2023-new-faculty-560x583.jpg 560w, https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2023\/08\/Zhijun-Li-phd-2023-new-faculty.jpg 650w\" sizes=\"auto, (max-width: 288px) 100vw, 288px\" \/><\/a><figcaption class=\"caption wp-caption-text\">Zhijun Li PhD, Research Assistant Professor in the Zhang lab<\/figcaption><\/figure>\n<p>My name is Zhijun Li; I am very excited for this opportunity to join BCBP and <a href=\"https:\/\/www.med.unc.edu\/biochem\/directory\/zhang\/\">Prof. Qi Zhang\u2019s Lab<\/a> as a Research Assistant Professor. \u00a0I received my Ph.D. in a joint program of science and engineering, from Saitama University and Cellular and Molecular Biology Unit of RIKEN in Japan. I hope my research projects, which bridge biochemistry, immunology, and cancer biology, both complement and enhance current efforts of our department to investigate fundamental mechanisms of biochemistry and biophysics, related to cancer development and to translate scientific discoveries into new treatments. Further, I am eager to share my expertise in biochemistry, biophysics, and cellular biology with the lab, department, and greater scientific communities.<\/p>\n<p>I have been a member of Dr. Yue Xiong and Dr. Al Baldwin\u2019s lab at the Lineberger Cancer Center, working on two cytoplasmically localized cullin-ring family E3 ligases, Cul9 and Cul7. I found that the functions of CUL9 in regulating cell proliferation and maintaining genomic integrity are mainly mediated by p53, and that CUL9 is a critical p53 activator. To understand the mechanistic role of CUL9, I established the mice model of Cul9 KO and Cul9-p53 binding deficient knock-in. Using those MEF cells I successfully identified Survivin as one of the critical substrates of CUL9 by mass spec-based proteomic approaches. Most recently, I have been studying the metabolic and epigenetic control of antitumor immunity and focused on the function of TET2 DNA dioxygenase that is frequently mutated in human hematopoietic malignancies to identify potential therapeutic targets for immunotherapy of solid tumors.<\/p>\n<p>I am excited to utilize my extensive experiences in these fields to contribute to our department\u2019s pursuit of basic science discoveries; specifically, towards the mechanism of RNA demethylation in immune response during tumor formation and advancing the understanding of cell immortalization. I am excited by the prospect of contributing to the rich community of researchers within the Department of Biochemistry and Biophysics and the UNC School of Medicine more broadly.<\/p>\n<p>I look forward to working with you all!<\/p>\n<p>Zhijun Li, Ph.D<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Meet Dr. Zhijun Li. He received his Ph.D. in a joint program of science and engineering, from Saitama University and Cellular and Molecular Biology Unit of RIKEN in Japan&#8230;<\/p>\n","protected":false},"author":41619,"featured_media":27236,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[10,385],"class_list":["post-27232","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news_faculty","tag-news_2023","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Zhijun Li PhD joins Qi Zhang\u2019s Lab as a Research Assistant Professor | Biochemistry and Biophysics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/biochem\/news\/zhijun-li-phd-joins-qi-zhangs-lab-as-a-research-assistant-professor\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zhijun Li PhD joins Qi Zhang\u2019s Lab as a Research Assistant Professor | Biochemistry and Biophysics\" \/>\n<meta property=\"og:description\" content=\"Meet Dr. Zhijun Li. He received his Ph.D. in a joint program of science and engineering, from Saitama University and Cellular and Molecular Biology Unit of RIKEN in Japan...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/biochem\/news\/zhijun-li-phd-joins-qi-zhangs-lab-as-a-research-assistant-professor\/\" \/>\n<meta property=\"og:site_name\" content=\"Biochemistry and Biophysics\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/uncbiochemistryandbiophysics\/\" \/>\n<meta property=\"article:published_time\" content=\"2023-08-15T16:01:38+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-16T15:33:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2023\/08\/image-od-new-faculty.png\" \/>\n\t<meta property=\"og:image:width\" content=\"378\" \/>\n\t<meta property=\"og:image:height\" content=\"385\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Carolyn Clabo\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UNC_BCBP\" \/>\n<meta name=\"twitter:site\" content=\"@UNC_BCBP\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Carolyn Clabo\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/biochem\/news\/zhijun-li-phd-joins-qi-zhangs-lab-as-a-research-assistant-professor\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/biochem\/news\/zhijun-li-phd-joins-qi-zhangs-lab-as-a-research-assistant-professor\/\"},\"author\":{\"name\":\"Carolyn Clabo\",\"@id\":\"https:\/\/www.med.unc.edu\/biochem\/#\/schema\/person\/9693a4e0a76e8208ca2105ae25587332\"},\"headline\":\"Zhijun Li PhD joins Qi Zhang\u2019s Lab as a Research Assistant Professor\",\"datePublished\":\"2023-08-15T16:01:38+00:00\",\"dateModified\":\"2023-08-16T15:33:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/biochem\/news\/zhijun-li-phd-joins-qi-zhangs-lab-as-a-research-assistant-professor\/\"},\"wordCount\":375,\"publisher\":{\"@id\":\"https:\/\/www.med.unc.edu\/biochem\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/biochem\/news\/zhijun-li-phd-joins-qi-zhangs-lab-as-a-research-assistant-professor\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/biochem\/wp-content\/uploads\/sites\/795\/2023\/08\/image-od-new-faculty.png\",\"keywords\":[\"Faculty &amp; 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