{"id":32437,"date":"2025-11-04T14:04:49","date_gmt":"2025-11-04T19:04:49","guid":{"rendered":"https:\/\/www.med.unc.edu\/biochem\/?p=32437"},"modified":"2025-11-05T07:29:49","modified_gmt":"2025-11-05T12:29:49","slug":"bcbp-team-awarded-multi-pi-r01-grant-from-nia-to-advance-aging-research","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/biochem\/news\/bcbp-team-awarded-multi-pi-r01-grant-from-nia-to-advance-aging-research\/","title":{"rendered":"BCBP Team Awarded Multi-PI R01 Grant from NIA to Advance Aging Research"},"content":{"rendered":"

We\u2019re\u00a0thrilled to announce that our team has been awarded a\u00a0<\/span>Multi-PI\u00a0R01 grant<\/span><\/b>\u00a0from the\u00a0<\/span>National Institute on Aging (NIA)<\/span><\/b>\u00a0for the project titled:\u00a0<\/span>\u00a0<\/span><\/p>\n

\u201cEpigenetic Regulation of Nuclear\u00a0cGAS\u00a0Activity in Aging-Related Inflammation\u201d<\/span><\/b>\u00a0<\/span>\u00a0<\/span><\/p>\n

The grant officially began on\u00a0<\/span>August 15, 2025<\/span><\/b>, and marks a major milestone for our collaborative research efforts.\u00a0<\/span>\u00a0<\/span><\/p>\n

Project Leadership<\/span><\/b>\u00a0<\/span><\/i>\u00a0<\/span><\/p>\n

This is a\u00a0<\/span>multi-PI initiative<\/span><\/b>\u00a0led by\u00a0<\/span>Qi Zhang\u00a0<\/span><\/b>and\u00a0<\/span>Pengda\u00a0Liu<\/span><\/b>, with key contributions from co-investigators\u00a0<\/span>Brian Strahl<\/span><\/b>\u00a0and\u00a0<\/span>Rob McGinty<\/span><\/b>.\u00a0<\/span>\u00a0<\/span><\/p>\n

\"Qi
Qi Zhang PhD<\/figcaption><\/figure>\n
\"Pengda
Pengda Liu PhD<\/figcaption><\/figure>\n
\"Dr.
Brian Strahl PhD<\/figcaption><\/figure>\n
\"Robert
Rob McGinty MD PhD<\/figcaption><\/figure>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

Research Focus<\/span><\/b>\u00a0<\/span><\/i>\u00a0<\/span><\/p>\n

The project explores how epigenetic mechanisms regulate nuclear\u00a0cGAS\u00a0activity, a critical pathway in aging-related inflammation. This work has the potential to uncover new therapeutic targets for age-associated diseases.\u00a0<\/span>\u00a0<\/span><\/p>\n

A True BCBP Team Effort<\/span><\/b>\u00a0<\/span><\/i>\u00a0<\/span><\/p>\n

This award reflects the strength of our\u00a0<\/span>Biochemistry and Biophysics <\/span><\/b>community and its commitment to advancing aging research through interdisciplinary collaboration.<\/span>\u00a0<\/span>Congratulations<\/span><\/span> to the Biochemistry and Biophysics Team!<\/span><\/span>\u00a0<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

We\u2019re\u00a0thrilled to announce that our team has been awarded a\u00a0Multi-PI\u00a0R01 grant\u00a0from the\u00a0National Institute on Aging (NIA)\u00a0for the project titled:\u00a0\u201cEpigenetic Regulation of Nuclear\u00a0cGAS\u00a0Activity in Aging-Related Inflammation.\u201d\u00a0This is a\u00a0multi-PI initiative\u00a0led by\u00a0Qi Zhang\u00a0and\u00a0Pengda\u00a0Liu, with key contributions from co-investigators\u00a0Brian Strahl\u00a0and\u00a0Rob McGinty.<\/p>\n","protected":false},"author":41619,"featured_media":12458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[10],"class_list":["post-32437","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news_faculty","odd"],"acf":[],"yoast_head":"\nBCBP Team Awarded Multi-PI R01 Grant from NIA to Advance Aging Research | Biochemistry and Biophysics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/biochem\/news\/bcbp-team-awarded-multi-pi-r01-grant-from-nia-to-advance-aging-research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BCBP Team Awarded Multi-PI R01 Grant from NIA to Advance Aging Research | Biochemistry and Biophysics\" \/>\n<meta property=\"og:description\" content=\"We\u2019re\u00a0thrilled to announce that our team has been awarded a\u00a0Multi-PI\u00a0R01 grant\u00a0from the\u00a0National Institute on Aging (NIA)\u00a0for the project titled:\u00a0\u201cEpigenetic Regulation of Nuclear\u00a0cGAS\u00a0Activity in Aging-Related Inflammation.\u201d\u00a0This is a\u00a0multi-PI initiative\u00a0led 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