{"id":3967,"date":"2011-08-02T19:20:00","date_gmt":"2011-08-02T23:20:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/biochem\/sancar-july-22-2011-cover-of-jbc\/"},"modified":"2018-08-01T10:23:40","modified_gmt":"2018-08-01T14:23:40","slug":"sancar-july-22-2011-cover-of-jbc","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/biochem\/news\/sancar-july-22-2011-cover-of-jbc\/","title":{"rendered":"Sancar lab featured on the cover of JBC published on July 22, 2011"},"content":{"rendered":"
\n

On the JBC Cover: The circadian clock is the internal timekeeping molecular system that generates a daily rhythm in an organism\u2019s physiology and behavior.<\/p>\n

\n
\n \"image2\"\/
From the cover of JBC issue July 22, 2011
\n <\/figcaption><\/figure>\n<\/div>\n
\n

Biochemical Analysis of the Canonical Model for the Mammalian Circadian Clock<\/b><\/i><\/a><\/p>\n

Authors: <\/b>Rui Ye, Christopher P. Selby, Nuri Ozturk, Yunus Annayev and Aziz Sancar<\/p>\n

Journal<\/b>: The Journal of Biological Chemistry<\/p>\n

Issue: <\/b>July 22, 2011 \u2013 <\/b>286, 25891-25902<\/p>\n

\n\n

On The Cover:<\/b> The circadian clock is the internal timekeeping molecular system that generates a daily rhythm in an organism\u2019s physiology and behavior. Based on genetic and cell biological experiments, a canonical model for the circadian clock in mammals consisting of TTFL has been developed. The paper by Rui Ye and colleagues describes the purification of the mammalian clock proteins and the first biochemical test of the model. Their findings support some aspects of the canonical model but also suggest that some key features of the model need to be revised. The cover picture is a whimsical illustration of the significance of biochemical analysis to the understanding of this complex behavioral system.<\/p>\n

Learn more: Sancar Lab<\/span><\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

<\/p>\n

On the JBC Cover: The circadian clock is the internal timekeeping molecular system that generates a daily rhythm in an organism’s physiology and behavior.<\/p>\n","protected":false},"author":12066,"featured_media":3968,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[10,16,4,17],"class_list":["post-3967","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news_faculty","tag-news_2011","tag-recent-news","tag-sancar_news","odd"],"acf":[],"yoast_head":"\nSancar lab featured on the cover of JBC published on July 22, 2011 | Biochemistry and Biophysics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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