{"id":2353,"date":"2026-01-12T15:20:57","date_gmt":"2026-01-12T20:20:57","guid":{"rendered":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/?page_id=2353"},"modified":"2026-01-21T10:49:02","modified_gmt":"2026-01-21T15:49:02","slug":"acute-myeloid-leukemia-associated-thrombosis-and-bleeding","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/research\/acute-myeloid-leukemia-associated-thrombosis-and-bleeding\/","title":{"rendered":"Acute myeloid leukemia-associated thrombosis and bleeding"},"content":{"rendered":"<div>Acute myeloid leukemia (AML) is associated with both venous thrombosis and bleeding. However, the mediators underlying these complications have not yet been elucidated. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2475037925006430\">We have recently developed a mouse xenograft model of AML<\/a> that mimics human disease, and we are currently establishing a mouse allograft model of AML. Using these models, we aim to investigate the mechanisms by which AML induces venous thrombosis and bleeding.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Acute myeloid leukemia (AML) is associated with both venous thrombosis and bleeding. However, the mediators underlying these complications have not yet been elucidated. We have recently developed a mouse xenograft model of AML that mimics human disease, and we are currently establishing a mouse allograft model of AML. Using these models, we aim to investigate &hellip; <a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/research\/acute-myeloid-leukemia-associated-thrombosis-and-bleeding\/\" aria-label=\"Read more about Acute myeloid leukemia-associated thrombosis and bleeding\">Read more<\/a><\/p>\n","protected":false},"author":42253,"featured_media":0,"parent":2319,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2353","page","type-page","status-publish","hentry","odd"],"acf":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/pages\/2353","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/users\/42253"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/comments?post=2353"}],"version-history":[{"count":2,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/pages\/2353\/revisions"}],"predecessor-version":[{"id":2417,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/pages\/2353\/revisions\/2417"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/pages\/2319"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/hisadalab\/wp-json\/wp\/v2\/media?parent=2353"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}