{"id":2239,"date":"2020-01-21T11:46:14","date_gmt":"2020-01-21T16:46:14","guid":{"rendered":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/?page_id=2239"},"modified":"2025-05-16T10:21:20","modified_gmt":"2025-05-16T14:21:20","slug":"unc-blood-research-center","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/","title":{"rendered":"UNC Blood Research Center"},"content":{"rendered":"<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-6 col-md-6 col-xs-12 col-sm-6 oscitas-bootstrap-container\">\n\n<!-- iframe plugin v.5.2 wordpress.org\/plugins\/iframe\/ -->\n<iframe loading=\"lazy\" src=\"https:\/\/uncch.hosted.panopto.com\/Panopto\/Pages\/Embed.aspx?id=5f74a318-a0ca-4081-969f-afd90131e888&#038;autoplay=false&#038;offerviewer=true&#038;showtitle=true&#038;showbrand=true&#038;captions=true&#038;interactivity=all\" height=\"405\" width=\"720\" style=\"border: 1px solid #464646;\" 0=\"allowfullscreen\" allow=\"autoplay\" scrolling=\"yes\" class=\"iframe-class\" frameborder=\"0\"><\/iframe>\n\n<p style=\"text-align: left;\"><\/div>\n<div class=\"col-lg-6 col-md-6 col-xs-12 col-sm-6 oscitas-bootstrap-container\">\n<a class=\"btn btn-primary btn-lg btn-block  oscitas-bootstrap-container\" target=\"_self\" href=\"https:\/\/bsky.app\/profile\/unc-brc.bsky.social\">Follow us at our Bluesky account @unc-brc.bsky.social<\/a>\n<div class=\"clean-quote\"><p>The UNC Blood Research Center (BRC) was established to promote interdisciplinary research in non-malignant blood disorders across UNC. It will seek to advance the work in the following specific areas.<br\/><\/p><\/div>\n<\/div>\n<\/div>\n<hr class=\" rule-thin osc-rule\" \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-6 col-md-6 col-xs-12 col-sm-6 oscitas-bootstrap-container\">\n<h2 class=\"www-somHeader\">Thrombosis<\/h2>\n<p>One in four of the US population will succumb to a terminal thrombotic event, such as: myocardial infarction, stroke, or venous thromboembolism.<\/p>\n<p>Basic science discoveries have paved the way towards better prophylactic and therapeutic approaches to thrombosis. However, a better understanding of the mechanisms underlying thrombosis and prevention without any risk of bleeding remains an unmet need. The BRC seeks to investigate potential approaches to both aims.<\/div>\n<div class=\"col-lg-6 col-md-6 col-xs-12 col-sm-6 oscitas-bootstrap-container\">\n<h2 class=\"www-somHeader\">Bleeding Disorders<\/h2>\n<p>UNC is a world leader in hemophilia, from the development and administration of the first coagulation factor VIII concentrate to the role of the Chapel Hill dog colonies of the Francis Owen Blood Research Center in the pre-clinical testing of protein and gene therapies. The BRC aims to address the broad challenges that remain in numerous other inherited and acquired bleeding disorders.<\/div>\n<\/div>\n<h2 class=\"www-somHeader\">Sickle Cell Disease<\/h2>\n<p>Sickle cell disease affects approximately 100,000 Americans but accounts for an estimated 300,000 births worldwide every year, primarily in sub-Saharan Africa and the Indian sub-continent.<\/p>\n<p>Compared to many other areas of medicine, the development of impactful therapies in sickle cell disease remains inadequate. We will continue to expand our research efforts to this under-served patient population into the future.<\/p>\n<hr \/>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-6 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<h2 class=\"www-somHeader\">Events\/Seminars<\/h2>\n<p class=\"www-somHeader\"><div class=\"event-calendar\"><div class=\"event-post\"><div class=\"event-date\"><time>May<span>26<\/span><\/time><\/div><div class=\"event-details\"><p>Tuesday 9:00 am<\/p><h4 class=\"media-heading\"><a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/event\/tuesday-brc-lab-meeting-78\/\" rel=\"bookmark\">Tuesday BRC Lab Meeting<\/a><\/h4><\/div><\/div><div class=\"event-post\"><div class=\"event-date\"><time>May<span>29<\/span><\/time><\/div><div class=\"event-details\"><p>Friday 11:00 am<\/p><h4 class=\"media-heading\"><a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/event\/brc-seminar-series-spring-2026-jing-fei-dong\/\" rel=\"bookmark\">BRC Seminar Series Spring 2026: Jing-Fei Dong<\/a><\/h4><\/div><\/div><div class=\"event-post\"><div class=\"event-date\"><time>Jun<span>09<\/span><\/time><\/div><div class=\"event-details\"><p>Tuesday 9:00 am<\/p><h4 class=\"media-heading\"><a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/event\/tuesday-brc-lab-meeting-75\/\" rel=\"bookmark\">Tuesday BRC Lab Meeting<\/a><\/h4><\/div><\/div><\/div><!-- .hfeed --><p class=\"tribe-events-widget-link\"><a class=\"btn btn-primary btn-sm\" href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/events\/\" rel=\"bookmark\">View All Events<\/a><\/p>\n<\/div>\n<div class=\"col-lg-6 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<\/div>\n<\/div>\n<h2 class=\"www-somHeader\"><span style=\"color: inherit;\">News<\/span><\/h2>\n        <div class=\"wc-cards-feature\">\n        <div class=\"wc-cards-feature__info\">            <h2 class=\"wc-cards-feature__title\">Recent Posts<\/h2>            <p class=\"wc-cards-feature__description\">News from the Blood Research Center<\/p>        <a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/category\/news\/\" class=\"wc-more-link\">More posts<\/a>        <\/div>\n        <div class=\"wc-cards\"><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2026\/05\/dr-leiderman-group-has-recently-published-two-papers-in-biophysical-journal\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2022\/08\/Karin-Leiderman-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"\" srcset=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2022\/08\/Karin-Leiderman-600x600.jpg 600w, https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2022\/08\/Karin-Leiderman-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">2 weeks ago<\/p><h3 class=\"wc-card__title wc-card__title--3\">Dr. Leiderman group has recently published two papers in Biophysical Journal<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Dr. Leiderman group has recently published two papers in Biophysical Journal. Han Cao first author paper: &#8220;Continuum and discrete modeling of binding-site distribution-mediated reactions on lipid surfaces\u201d collaborative with Anirban Sen Gupta. \u00a0Link to paper: https:\/\/www.cell.com\/biophysj\/fulltext\/S0006-3495(26)00187-6 A collaborative effort Dr. Leiderman was a part of as a co-mentor to the first author who is not &hellip;<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Dr. Leiderman group has recently published two papers in Biophysical Journal\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2026\/05\/leyi-zhang-won-a-poster-award-at-the-12th-symposium-on-hemostasis\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2026\/05\/leyi-zhang-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"\" srcset=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2026\/05\/leyi-zhang-600x600.jpg 600w, https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2026\/05\/leyi-zhang-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">2 weeks ago<\/p><h3 class=\"wc-card__title wc-card__title--3\">Leyi Zhang won a poster award at the 12th Symposium on Hemostasis<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Dr. Karin Leiderman&#8217;s grad student Leyi Zhang won a poster award at the 12th Symposium on Hemostasis. It was entitled: &#8220;Mathematical Modeling of Management of Postoperative Bleeding in Cardiac Surgery\u201d. This work is also collaborative with Dr. Kenichi Tanaka.<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Leyi Zhang won a poster award at the 12th Symposium on Hemostasis\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article><article class=\"wc-card wc-card--1x1 wc-card--zoom\"><a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2026\/05\/jamie-madrigal-was-awarded-the-journal-of-thrombosis-and-haemostasis-editors-award\/\" class=\"wc-card__link-wrap\"><div class=\"wc-card__image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2026\/05\/madrigal-600x600.jpg\" class=\"attachment-wc_card_1x1 size-wc_card_1x1 wp-post-image\" alt=\"\" srcset=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2026\/05\/madrigal-600x600.jpg 600w, https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2026\/05\/madrigal-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\"><\/div><div class=\"wc-card__header\"><p class=\"wc-card__date\">2 weeks ago<\/p><h3 class=\"wc-card__title wc-card__title--3\">Jamie Madrigal was awarded the Journal of Thrombosis and Haemostasis Editor\u2019s award.<\/h3><\/div><div class=\"wc-card__content\"><p class=\"wc-card__excerpt wc-card__excerpt--5\">Jamie Madrigal, previous student of Dr. Karin Leiderman, was awarded the Journal of Thrombosis and Haemostasis Editor\u2019s award. Here is the link to that: https:\/\/www.isth.org\/news\/726139\/Journal-of-Thrombosis-and-Haemostasis-announces-2026-Editors-Awards-recipients.htm<\/p><p class=\"wc-card__more\" aria-label=\"Read more about Jamie Madrigal was awarded the Journal of Thrombosis and Haemostasis Editor\u2019s award.\"><span class=\"wc-card__more-text\" aria-hidden=\"true\">Read more<\/span><\/p><\/div><\/a><\/article>        <\/div>\n        <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Sickle Cell Disease Sickle cell disease affects approximately 100,000 Americans but accounts for an estimated 300,000 births worldwide every year, primarily in sub-Saharan Africa and the Indian sub-continent. Compared to many other areas of medicine, the development of impactful therapies in sickle cell disease remains inadequate. We will continue to expand our research efforts to &hellip; <a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2026\/05\/jamie-madrigal-was-awarded-the-journal-of-thrombosis-and-haemostasis-editors-award\/\" aria-label=\"Read more about Jamie Madrigal was awarded the Journal of Thrombosis and Haemostasis Editor\u2019s award.\">Read more<\/a><\/p>\n","protected":false},"author":79967,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2239","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>UNC Blood Research Center | UNC Blood Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"UNC Blood Research Center | UNC Blood Research Center\" \/>\n<meta property=\"og:description\" content=\"Sickle Cell Disease Sickle cell disease affects approximately 100,000 Americans but accounts for an estimated 300,000 births worldwide every year, primarily in sub-Saharan Africa and the Indian sub-continent. Compared to many other areas of medicine, the development of impactful therapies in sickle cell disease remains inadequate. 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Compared to many other areas of medicine, the development of impactful therapies in sickle cell disease remains inadequate. 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