{"id":3320,"date":"2020-07-16T11:33:05","date_gmt":"2020-07-16T15:33:05","guid":{"rendered":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/?p=3320"},"modified":"2020-08-23T09:27:00","modified_gmt":"2020-08-23T13:27:00","slug":"r01-awarded-to-co-investigator-dr-raj-kasthuri-title-iron-sensitive-rna-regulation-during-erythropoiesis","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2020\/07\/r01-awarded-to-co-investigator-dr-raj-kasthuri-title-iron-sensitive-rna-regulation-during-erythropoiesis\/","title":{"rendered":"R01 awarded to Dr. Maria Aleman (PI), Dr. Raj Kasthuri and Dr. Daniel Dominguez (Co-Is) Title: Iron-sensitive RNA regulation during erythropoiesis"},"content":{"rendered":"<p>Congratulations- R01 awarded to Dr. Maria Aleman (PI), R01 was awarded on a $2 million (direct costs only) 5-year R01 grant; funding period (2020-2025).\u00a0\u00a0 Scientific team includes outstanding scientists and collaborators, Co-Investigators Dr. Raj Kasthuri and Dr. Daniel Dominguez (not pictured).<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3360\" src=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/07\/Maria-Aleman.jpg\" alt=\"Maria Aleman\" width=\"130\" height=\"150\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-2420\" src=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/01\/Raj_Kasthuri-214x300.jpeg\" alt=\"\" width=\"108\" height=\"151\" srcset=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/01\/Raj_Kasthuri-214x300.jpeg 214w, https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/01\/Raj_Kasthuri.jpeg 548w\" sizes=\"auto, (max-width: 108px) 100vw, 108px\" \/><\/p>\n<p>Institute: NIH\/NIDDK (1R01DK124773-01)<br \/>\nTitle: Iron-sensitive RNA regulation during erythropoiesis<br \/>\nPI: Maria Aleman PhD (Pharmacology); Co-investigators: Raj Kasthuri, MD (Medicine), Daniel Dominguez, PhD (Pharmacology)<\/p>\n<p>PROJECT NARRATIVE Iron deficiency is the most common nutritional deficit worldwide and the #1 cause of anemia. The primary goal of this proposal is to define mechanisms by which iron modulates the activity of a family of RNA binding proteins which double as intracellular iron chaperones. This research program is highly relevant to public health because it will uncover basic mechanisms that become dysregulated with iron deficiency.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations- R01 awarded to Dr. Maria Aleman (PI), R01 was awarded on a $2 million (direct costs only) 5-year R01 grant; funding period (2020-2025).\u00a0\u00a0 Scientific team includes outstanding scientists and collaborators, Co-Investigators Dr. Raj Kasthuri and Dr. Daniel Dominguez (not pictured). Institute: NIH\/NIDDK (1R01DK124773-01) Title: Iron-sensitive RNA regulation during erythropoiesis PI: Maria Aleman PhD (Pharmacology); &hellip; <a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2020\/07\/r01-awarded-to-co-investigator-dr-raj-kasthuri-title-iron-sensitive-rna-regulation-during-erythropoiesis\/\" aria-label=\"Read more about R01 awarded to Dr. Maria Aleman (PI), Dr. Raj Kasthuri and Dr. Daniel Dominguez (Co-Is) Title: Iron-sensitive RNA regulation during erythropoiesis\">Read more<\/a><\/p>\n","protected":false},"author":15383,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-3320","post","type-post","status-publish","format-standard","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>R01 awarded to Dr. Maria Aleman (PI), Dr. Raj Kasthuri and Dr. Daniel Dominguez (Co-Is) Title: Iron-sensitive RNA regulation during erythropoiesis | UNC Blood Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2020\/07\/r01-awarded-to-co-investigator-dr-raj-kasthuri-title-iron-sensitive-rna-regulation-during-erythropoiesis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"R01 awarded to Dr. Maria Aleman (PI), Dr. Raj Kasthuri and Dr. Daniel Dominguez (Co-Is) Title: Iron-sensitive RNA regulation during erythropoiesis | UNC Blood Research Center\" \/>\n<meta property=\"og:description\" content=\"Congratulations- R01 awarded to Dr. Maria Aleman (PI), R01 was awarded on a $2 million (direct costs only) 5-year R01 grant; funding period (2020-2025).\u00a0\u00a0 Scientific team includes outstanding scientists and collaborators, Co-Investigators Dr. Raj Kasthuri and Dr. Daniel Dominguez (not pictured). 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