{"id":3627,"date":"2020-12-09T13:01:06","date_gmt":"2020-12-09T18:01:06","guid":{"rendered":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/?p=3627"},"modified":"2020-12-09T13:58:28","modified_gmt":"2020-12-09T18:58:28","slug":"nc-tracs-grant-awarded-to-silvio-antoniak-phd","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2020\/12\/nc-tracs-grant-awarded-to-silvio-antoniak-phd\/","title":{"rendered":"NC TraCS Grant awarded to Silvio Antoniak, PHD"},"content":{"rendered":"<p>Congratulations to Silvio Antoniak, Phd with NCSU collaborator James C. Bonner!<\/p>\n<p>Grant application titled \u201cRole of PAR-2 in nanoparticle modulation of allergic lung disease\u201d<br \/>\nThe NC TraCS proposal investigates the contribution of lung macrophage PAR2 on allergic airway disease caused by multi-walled carbon nanotubes (MWCNTs). We propose that common allergens like house dust mite allergens form an \u2018allergen corona\u2019 on the surface of the MWCNTs. This specific \u2018allergen corona\u2019 exhibit proteolytic activity leading to PAR2 activation within the lung. \u00a0PAR2 signaling especially on lung macrophages increases and exacerbate the allergic airways disease.<\/p>\n<figure id=\"attachment_2350\" class=\"thumbnail wp-caption alignnone\" style=\"width: 198px\"><a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2019\/12\/silvio-antoniak.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2350\" src=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2019\/12\/silvio-antoniak.jpg\" alt=\"\" width=\"188\" height=\"250\" \/><\/a><figcaption class=\"caption wp-caption-text\">Silvio Antoniak, PhD<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations to Silvio Antoniak, Phd with NCSU collaborator James C. Bonner! Grant application titled \u201cRole of PAR-2 in nanoparticle modulation of allergic lung disease\u201d The NC TraCS proposal investigates the contribution of lung macrophage PAR2 on allergic airway disease caused by multi-walled carbon nanotubes (MWCNTs). We propose that common allergens like house dust mite allergens &hellip; <a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2020\/12\/nc-tracs-grant-awarded-to-silvio-antoniak-phd\/\" aria-label=\"Read more about NC TraCS Grant awarded to Silvio Antoniak, PHD\">Read more<\/a><\/p>\n","protected":false},"author":15383,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-3627","post","type-post","status-publish","format-standard","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>NC TraCS Grant awarded to Silvio Antoniak, PHD | UNC Blood Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2020\/12\/nc-tracs-grant-awarded-to-silvio-antoniak-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NC TraCS Grant awarded to Silvio Antoniak, PHD | UNC Blood Research Center\" \/>\n<meta property=\"og:description\" content=\"Congratulations to Silvio Antoniak, Phd with NCSU collaborator James C. Bonner! Grant application titled \u201cRole of PAR-2 in nanoparticle modulation of allergic lung disease\u201d The NC TraCS proposal investigates the contribution of lung macrophage PAR2 on allergic airway disease caused by multi-walled carbon nanotubes (MWCNTs). We propose that common allergens like house dust mite allergens &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2020\/12\/nc-tracs-grant-awarded-to-silvio-antoniak-phd\/\" \/>\n<meta property=\"og:site_name\" content=\"UNC Blood Research Center\" \/>\n<meta property=\"article:published_time\" content=\"2020-12-09T18:01:06+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-12-09T18:58:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2019\/12\/silvio-antoniak.jpg\" \/>\n<meta name=\"author\" content=\"Christine Hill\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Christine Hill\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" 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