{"id":4327,"date":"2022-04-04T13:13:57","date_gmt":"2022-04-04T17:13:57","guid":{"rendered":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/?p=4327"},"modified":"2022-04-04T13:25:11","modified_gmt":"2022-04-04T17:25:11","slug":"dr-robert-lee-published","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/","title":{"rendered":"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight<\/i>"},"content":{"rendered":"

\"\"<\/p>\n

Platelet homeostasis, i.e. a stable platelet count in the circulation, is dependent on a tight regulation of both platelet production and clearance. Dr. Robert Lee, in collaboration with members of the Bergmeier lab, the Flick lab, and international collaborators, recently published their studies on the effect of uninhibited signaling by the small GTPase Rap1 on platelet homeostasis. Their findings, published in the Journal of Clinical Investigation Insight<\/em>, describe a novel, integrin-based mechanism of platelet clearance that could be critical for our understanding of select inherited and acquired thrombocytopenias.<\/p>\n

Click here to read the published study.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Platelet homeostasis, i.e. a stable platelet count in the circulation, is dependent on a tight regulation of both platelet production and clearance. Dr. Robert Lee, in collaboration with members of the Bergmeier lab, the Flick lab, and international collaborators, recently published their studies on the effect of uninhibited signaling by the small GTPase Rap1 on … Journal of Clinical Investigation Insight<\/i>“>Read more<\/a><\/p>\n","protected":false},"author":112194,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-4327","post","type-post","status-publish","format-standard","hentry","category-news","odd"],"acf":[],"yoast_head":"\nDr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight | UNC Blood Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight | UNC Blood Research Center\" \/>\n<meta property=\"og:description\" content=\"Platelet homeostasis, i.e. a stable platelet count in the circulation, is dependent on a tight regulation of both platelet production and clearance. Dr. Robert Lee, in collaboration with members of the Bergmeier lab, the Flick lab, and international collaborators, recently published their studies on the effect of uninhibited signaling by the small GTPase Rap1 on … Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/\" \/>\n<meta property=\"og:site_name\" content=\"UNC Blood Research Center\" \/>\n<meta property=\"article:published_time\" content=\"2022-04-04T17:13:57+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-04-04T17:25:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee-214x300.jpg\" \/>\n<meta name=\"author\" content=\"amshespe\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"amshespe\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/\"},\"author\":{\"name\":\"amshespe\",\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#\/schema\/person\/260407197a0758362b2233f07aa78729\"},\"headline\":\"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight\",\"datePublished\":\"2022-04-04T17:13:57+00:00\",\"dateModified\":\"2022-04-04T17:25:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/\"},\"wordCount\":107,\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee-214x300.jpg\",\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/\",\"url\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/\",\"name\":\"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight | UNC Blood Research Center\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee-214x300.jpg\",\"datePublished\":\"2022-04-04T17:13:57+00:00\",\"dateModified\":\"2022-04-04T17:25:11+00:00\",\"author\":{\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#\/schema\/person\/260407197a0758362b2233f07aa78729\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee.jpg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee.jpg\",\"width\":285,\"height\":400},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/\",\"name\":\"UNC Blood Research Center\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#\/schema\/person\/260407197a0758362b2233f07aa78729\",\"name\":\"amshespe\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/33be13405b42e0c3ce651a66d1f7b8ad48d3b4eab5cd3ccc001ba6f4d92d9d71?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/33be13405b42e0c3ce651a66d1f7b8ad48d3b4eab5cd3ccc001ba6f4d92d9d71?s=96&d=mm&r=g\",\"caption\":\"amshespe\"},\"url\":\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/author\/amshespe\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight | UNC Blood Research Center","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/","og_locale":"en_US","og_type":"article","og_title":"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight | UNC Blood Research Center","og_description":"Platelet homeostasis, i.e. a stable platelet count in the circulation, is dependent on a tight regulation of both platelet production and clearance. Dr. Robert Lee, in collaboration with members of the Bergmeier lab, the Flick lab, and international collaborators, recently published their studies on the effect of uninhibited signaling by the small GTPase Rap1 on … Read more","og_url":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/","og_site_name":"UNC Blood Research Center","article_published_time":"2022-04-04T17:13:57+00:00","article_modified_time":"2022-04-04T17:25:11+00:00","og_image":[{"url":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee-214x300.jpg","type":"","width":"","height":""}],"author":"amshespe","twitter_card":"summary_large_image","twitter_misc":{"Written by":"amshespe","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#article","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/"},"author":{"name":"amshespe","@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#\/schema\/person\/260407197a0758362b2233f07aa78729"},"headline":"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight","datePublished":"2022-04-04T17:13:57+00:00","dateModified":"2022-04-04T17:25:11+00:00","mainEntityOfPage":{"@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/"},"wordCount":107,"image":{"@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee-214x300.jpg","articleSection":["News"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/","url":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/","name":"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight | UNC Blood Research Center","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#primaryimage"},"image":{"@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee-214x300.jpg","datePublished":"2022-04-04T17:13:57+00:00","dateModified":"2022-04-04T17:25:11+00:00","author":{"@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#\/schema\/person\/260407197a0758362b2233f07aa78729"},"breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#primaryimage","url":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee.jpg","contentUrl":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-content\/uploads\/sites\/1089\/2020\/02\/Bobby-H.-Lee.jpg","width":285,"height":400},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2022\/04\/dr-robert-lee-published\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/"},{"@type":"ListItem","position":2,"name":"Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#website","url":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/","name":"UNC Blood Research Center","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#\/schema\/person\/260407197a0758362b2233f07aa78729","name":"amshespe","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/33be13405b42e0c3ce651a66d1f7b8ad48d3b4eab5cd3ccc001ba6f4d92d9d71?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/33be13405b42e0c3ce651a66d1f7b8ad48d3b4eab5cd3ccc001ba6f4d92d9d71?s=96&d=mm&r=g","caption":"amshespe"},"url":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/author\/amshespe\/"}]}},"featured_image":false,"featured_image_medium":false,"featured_image_medium_large":false,"featured_image_large":false,"featured_image_thumbnail":false,"featured_image_alt":false,"category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/category\/news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/posts\/4327","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/users\/112194"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/comments?post=4327"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/posts\/4327\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/media?parent=4327"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/categories?post=4327"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/wp-json\/wp\/v2\/tags?post=4327"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}