{"id":6015,"date":"2024-05-21T10:12:39","date_gmt":"2024-05-21T14:12:39","guid":{"rendered":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/?p=6015"},"modified":"2024-05-21T10:12:39","modified_gmt":"2024-05-21T14:12:39","slug":"stephan-moll-md-gets-article-published-in-nejm","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2024\/05\/stephan-moll-md-gets-article-published-in-nejm\/","title":{"rendered":"Stephan Moll, MD gets article published in NEJM"},"content":{"rendered":"<p>Dr. Stephan Moll coauthored an article published on May 15, 2024 in the <em>New England Journal of Medicine<\/em> (<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc240259\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc240259<\/a> ) expanding on an earlier observation (Warkentin TE et al. <a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc2307721\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc2307721<\/a> ) that adenoviral infection can be associated with a clinical picture of severe thrombosis and thrombocytopenia, triggered by antibody formation against platelet factor 4 (PF4), similar to but distinct from heparin-induced thrombocytopenia, and similar to adeno-virus vector COVID-vaccine associated VITT (vaccine-induced immune thrombocytopenia).<\/p>\n<p>The current study entitled \u201c<em>Antibody Fingerprints Linking Adenoviral Anti-PF4 Disorders\u201c <\/em>further characterized the anti-PF4 antibodies from four patients with an adenoviral infection associated anti-PF4 disorder and found highly similar amino acid fingerprints of their antibodies\u2019 antigen-binding sites, leading to superimposable molecular structures of these anti-PF4 antibodies with anti-PF4 antibodies identified in patients with vaccine-induced immune thrombocytopenia (VITT).<\/p>\n<p><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc2402592\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc2402592<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Stephan Moll coauthored an article published on May 15, 2024 in the New England Journal of Medicine (https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc240259 ) expanding on an earlier observation (Warkentin TE et al. https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc2307721 ) that adenoviral infection can be associated with a clinical picture of severe thrombosis and thrombocytopenia, triggered by antibody formation against platelet factor 4 (PF4), &hellip; <a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2024\/05\/stephan-moll-md-gets-article-published-in-nejm\/\" aria-label=\"Read more about Stephan Moll, MD gets article published in NEJM\">Read more<\/a><\/p>\n","protected":false},"author":116232,"featured_media":2431,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-6015","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Stephan Moll, MD gets article published in NEJM | UNC Blood Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2024\/05\/stephan-moll-md-gets-article-published-in-nejm\/\" \/>\n<meta property=\"og:locale\" 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