{"id":6819,"date":"2025-10-15T09:16:57","date_gmt":"2025-10-15T13:16:57","guid":{"rendered":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/?p=6819"},"modified":"2025-10-15T09:16:57","modified_gmt":"2025-10-15T13:16:57","slug":"sam-short-md-and-collaborators-mentors-from-the-regards-study-published-two-papers-in-jth-about-stroke-risk-in-atrial-fibrillation","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2025\/10\/sam-short-md-and-collaborators-mentors-from-the-regards-study-published-two-papers-in-jth-about-stroke-risk-in-atrial-fibrillation\/","title":{"rendered":"Sam Short, MD and collaborators\/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation.\u00a0"},"content":{"rendered":"<div class=\"x_elementToProof\" data-olk-copy-source=\"MessageBody\">UNC Hem\/Onc Fellow Sam Short, MD and collaborators\/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation.<\/div>\n<div class=\"x_elementToProof\"><\/div>\n<ul data-editing-info=\"{&quot;applyListStyleFromLevel&quot;:false,&quot;unorderedStyleType&quot;:2}\">\n<li>\n<div class=\"x_elementToProof\" role=\"presentation\">Improving stroke risk prediction in atrial fibrillation with \u00a0circulating biomarkers: the CHA2DS2-VASc\u2013Biomarkers model\u00a0(DOI:\u00a0<a id=\"OWA727120c4-fba3-385e-72d7-dd3b3daa26d5\" class=\"x_OWAAutoLink\" title=\"Original URL: https:\/\/doi.org\/10.1016\/j.jtha.2025.06.007. Click or tap if you trust this link.\" href=\"https:\/\/nam12.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.jtha.2025.06.007&amp;data=05%7C02%7C%7Cc70ec84974824322365e08de098e1f8c%7C58b3d54f16c942d3af081fcabd095666%7C1%7C0%7C638958703218894415%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=jvG1Un1s%2BxiUTz1ePwhzhkzLFOvjZ3IA9PT3RsxmDOI%3D&amp;reserved=0\" data-auth=\"NotApplicable\" data-linkindex=\"0\">10.1016\/j.jtha.2025.06.007<\/a>)<\/div>\n<\/li>\n<li>\n<div class=\"x_elementToProof\" role=\"presentation\">Circulating biomarkers and ischemic stroke risk in adults with \u00a0atrial fibrillation taking anticoagulation: the Reasons for \u00a0Geographic And Racial Differences in Stroke study (DOI:\u00a0<a id=\"OWA3ea12045-3443-d2ea-1c05-581f9ffd05ac\" class=\"x_OWAAutoLink\" title=\"Original URL: https:\/\/doi.org\/10.1016\/j.jtha.2025.05.029. Click or tap if you trust this link.\" href=\"https:\/\/nam12.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.jtha.2025.05.029&amp;data=05%7C02%7C%7Cc70ec84974824322365e08de098e1f8c%7C58b3d54f16c942d3af081fcabd095666%7C1%7C0%7C638958703218917033%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=%2FEFp6Zq6ghc7J8h1F4HAICzl390eIEJuoBWJVqnhP18%3D&amp;reserved=0\" data-auth=\"NotApplicable\" data-linkindex=\"1\">10.1016\/j.jtha.2025.05.029<\/a>)<\/div>\n<\/li>\n<\/ul>\n<div class=\"x_elementToProof\"><\/div>\n<div class=\"x_elementToProof\">These studies examined whether circulating biomarkers could improve modeling of stroke risk in people with atrial fibrillation not on anticoagulation (to consider this) and, secondarily, among those already taking anticoagulation to examine residual risk. They developed a new clinical risk calculator (the CHA2DS2-VASc\u2013Biomarkers model) which improved CHA2DS2-VASc stroke risk prediction by adding NTproBNP and GDF15. They also found differences in associations for various biomarkers by anticoagulant use. Findings are relevant to those wishing to understand pathways to stroke \u00a0and anticoagulant prescription strategies in atrial fibrillation.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>UNC Hem\/Onc Fellow Sam Short, MD and collaborators\/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation. Improving stroke risk prediction in atrial fibrillation with \u00a0circulating biomarkers: the CHA2DS2-VASc\u2013Biomarkers model\u00a0(DOI:\u00a010.1016\/j.jtha.2025.06.007) Circulating biomarkers and ischemic stroke risk in adults with \u00a0atrial fibrillation taking anticoagulation: the Reasons for \u00a0Geographic And Racial &hellip; <a href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2025\/10\/sam-short-md-and-collaborators-mentors-from-the-regards-study-published-two-papers-in-jth-about-stroke-risk-in-atrial-fibrillation\/\" aria-label=\"Read more about Sam Short, MD and collaborators\/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation.\u00a0\">Read more<\/a><\/p>\n","protected":false},"author":117184,"featured_media":6820,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-6819","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sam Short, MD and collaborators\/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation.\u00a0 | UNC Blood Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2025\/10\/sam-short-md-and-collaborators-mentors-from-the-regards-study-published-two-papers-in-jth-about-stroke-risk-in-atrial-fibrillation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sam Short, MD and collaborators\/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation.\u00a0 | UNC Blood Research Center\" \/>\n<meta property=\"og:description\" content=\"UNC Hem\/Onc Fellow Sam Short, MD and collaborators\/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation. Improving stroke risk prediction in atrial fibrillation with \u00a0circulating biomarkers: the CHA2DS2-VASc\u2013Biomarkers model\u00a0(DOI:\u00a010.1016\/j.jtha.2025.06.007) Circulating biomarkers and ischemic stroke risk in adults with \u00a0atrial fibrillation taking anticoagulation: the Reasons for \u00a0Geographic And Racial &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/bloodresearchcenter\/2025\/10\/sam-short-md-and-collaborators-mentors-from-the-regards-study-published-two-papers-in-jth-about-stroke-risk-in-atrial-fibrillation\/\" \/>\n<meta property=\"og:site_name\" content=\"UNC Blood Research Center\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-15T13:16:57+00:00\" \/>\n<meta name=\"author\" content=\"martimic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"martimic\" \/>\n\t<meta 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