BRIC Seminar Series September 2016

Join us for a presentation by Dr. Yihong Yang, Chief of fMRI Section, NIDA.

When Sep 14, 2016
from 12:00 PM to 01:00 PM
Where Marsico 4004
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Yihong Yang 9_14_16 Seminar SeriesJoin us on September 14, 2016 at 12:00 PM in Marsico Hall, room 4004, for a presentation of "Searching for neuroimaging-based biomarkers of brain disorders" by Dr. Yihong Yang, Chief of fMRI Section, NIDA. 


There has been growing interest in identifying system-level biomarkers of brain disorders using neuroimaging technology. Specifically, intrinsic brain activity at “rest” has been used to reveal brain functions in healthy populations and dysfunctions in patients with neurological or psychiatric disorders. In this seminar, the neurophysiological basis of the resting-state brain activity will be discussed, and applications of resting-state fMRI in clinical studies and in animal models will be demonstrated.

Relevant publications:

H. Lu, Q. Zou, H. Gu, M. Raichle, E. A. Stein, Y. Yang. Rats Also Possess a Default Mode Brain Network. Proc. Natl. Acad. Sci. U.S.A. 109: 3979-3984 (2012).

X. Liang, Q. Zou, Y. He, Y. Yang. Coupling of functional connectivity and regional cerebral blood flow reveals a physiological basis for network hubs of the human brain. Proc Natl Acad Sci U S A. 110:1929-34 (2013).

Y. Hu, X. Chen, H. Gu, Y. Yang. Resting-state glutamate and GABA concentrations predict task-induced deactivation in the default mode network. J. Neuroscience 33:18566-18573 (2013).

Y. Hu, B. J. Salmeron, H. Gu, E.A. Stein, Y. Yang. Impaired functional connectivity within and between frontostriatal circuits is associated with compulsive drug use and trait impulsivity in cocaine addiction. JAMA Psychiatry 76: 584-592 (2015).

X. Liang, Q. Zou, Y. He, and Y. Yang. Topologically reorganized connectivity architecture of default-mode, executive-control and salience networks across working memory task loads. Cereb Cortex 26: 1501-1511 (2016).