{"id":8139,"date":"2025-08-27T10:26:55","date_gmt":"2025-08-27T14:26:55","guid":{"rendered":"https:\/\/www.med.unc.edu\/bric\/?page_id=8139"},"modified":"2025-08-27T15:02:48","modified_gmt":"2025-08-27T19:02:48","slug":"ultrasound","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/bric\/preclinical-molecular-imaging\/pmi-equipment\/ultrasound\/","title":{"rendered":"Ultrasound Imaging"},"content":{"rendered":"
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Instruments<\/strong><\/h3>\n\n\n\n
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Vevo-F2<\/em><\/h4>\n

The BRIC Preclinical Molecular Imaging (PMI) core facility has recently received a new animal ultrasound imaging system through a NIH S10 shared instrumentation grant (S10-OD034328). The new system, Vevo-F2 (Fujifilm VisualSonics, Inc), will replace the old Vevo-2100 system that has been serving more than 25 research labs in our community. The new system greatly enhance animal ultrasound imaging capability in the PMI facility. Some new features of the new ultrasound imaging system include:<\/p>\n

Main Imaging Features<\/p>\n

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  • Six imaging transducers with wide frequency coverage (from 5~ 50 MHz), allowing imaging from mice to small dogs\/cats. These will provide either high resolution imaging down to 30 \u03bcm, or deep penetration up to 15 mm for larger animals.<\/li>\n
  • Superior image quality with HD image processing technology, leading to the reduction in speckle noise and artifacts while enhancing tissue contrast<\/li>\n
  • 4D imaging allowing users to capture dynamic motions in 3D fashion, for example, a complete cardiac cycle in 3D volume.<\/li>\n
  • Super-fast frame rates (as high as 10,000 frames-per-second) for dynamic acquisition and processing including contrast enhanced imaging;<\/li>\n
  • Touchpad interface with enhanced workflow<\/li>\n
  • Three active transfer ports allowing switching between one to another transducer seamlessly<\/li>\n
  • Additional image analysis packages: Auto-LV (automatic LV analysis in B-mode and M-mode); VevoStrain (cardiac strain analysis); VevoVasc (vascular tissue analysis); VevoCQ(microbubble contrast enhanced image analysis for tissue perfusion).<\/li>\n<\/ul>\n

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The Vevo-F2 ultrasound imaging system is funded by an NIH shared instrumentation grant, 1S10OD034328. When data collected from the Vevo-F2 ultrasound imaging system results in any publications, please include the following in the acknowledgement:<\/b><\/p>\n

“Ultrasound Imaging is supported by the Preclinical Molecular Imaging Core Facility at UNC Biomedical Imaging Research Center (BRIC), and the ultrasound imaging system was funded by an NIH shared instrumentation grant, S10OD034328”<\/b><\/p>\n\n\n\n
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Vevo-2100<\/em><\/h4>\n

The BRIC is home to a Vevo-2100 ultrasound system (Fujifilm Visualsonics, Inc) which is located in upper basement of the Genetic Medicine Building vivarium.\u00a0 Users who want to use the Vevo-2100 system in GMB are required to have their animals housed in the GMB Vivarium. We offer several transducer options, and analysis and imaging packages to optimize your imaging study.<\/p>\n

Main Imaging Features<\/p>\n

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  • Several imaging modes available<\/li>\n
  • Multiple foci covering a larger field of view<\/li>\n
  • 3D imaging<\/li>\n
  • VevoCQ analysis software package for easy quantification<\/li>\n
  • Ultrasound guided injection<\/li>\n<\/ul>\n<\/td>\n

\"Vevo_2100\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
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Sample Images and Study Examples<\/strong><\/h3>\n

To see sample images from our optical imaging systems please follow this\u00a0link<\/a>.<\/p>\n

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Imaging Applications and Examples<\/strong><\/h3>\n