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January 3, 2022

Rapid Diagnostic Tests to Improve Antibiotic Stewardship for Pediatric Acute Respiratory Illnesses in Uganda

Globally, respiratory illness is one of the most common reasons that children seek care. It is often treated inappropriately with antibiotics, which can drive the development of antibiotic resistance. In resource-rich settings, testing for specific pathogens or measurement of clinical biomarkers, such as procalcitonin and C-reactive protein, is often employed to help determine which children …

graph of EAT free days

December 20, 2021

Early De-escalation of Empiric Antimicrobial Therapy in Acute Leukemia Patients with Febrile Neutropenia

CASP’s Bill Wilson, PharmD, Clinical Pharmacy Specialist, Infectious Diseases & Antimicrobial Stewardship in the UNC Children’s Hospital, was among the authors on a new article published today in Journal of Oncology Pharmacy Practice. Recent trials have shown early de-escalation of empiric antimicrobial therapy (EAT) in febrile neutropenia has led to less adverse effects with no …

Handle antimicrobials with care

November 17, 2021

Shortest Effective Durations of Antimicrobial Therapy focus of CASP’s observance of World Antimicrobials Awareness Week

More than half of all patients receive at least one antimicrobial agent during their hospital stay. At the Medical Center as with other facilities, patients sometimes receive treatment that is longer than needed for common infections. Reducing unnecessary antimicrobial exposure is essential to preserving the efficacy of these drugs for the future. Carolina Antimicrobial Stewardship …

cover of PIDS journal

June 15, 2021

Molecular Testing in Antimicrobial Stewardship

Antimicrobial resistance is a major global public health threat, and growing evidence suggests that antimicrobial-resistant infections are becoming increasingly common in children. Early selection of appropriate antimicrobial therapy can improve clinical outcomes and decrease exposure to unnecessary antimicrobials. For this reason, the 2016 Infectious Diseases Society of America guidelines for implementing an antimicrobial stewardship program …

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