{"id":2273,"date":"2014-12-05T19:55:00","date_gmt":"2014-12-06T00:55:00","guid":{"rendered":"https:\/\/med.sites.unc.edu\/cedas\/research-1\/other-research-studies\/"},"modified":"2024-02-22T14:47:01","modified_gmt":"2024-02-22T19:47:01","slug":"other-research-studies","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/cedas\/research-1\/other-research-studies\/","title":{"rendered":"Other Gastroenterology Research Studies"},"content":{"rendered":"

Currently Enrolling<\/h1>\n\n\n\n\n
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Trial of Oral IW-3718 Administered to Patients with Gastroesophageal Reflux Disease while receiving Proton Pump Inhibitors
\n<\/strong>Currently enrolling<\/p>\n

Purpose:<\/strong> To evaluate the safety and efficacy of IW-3718 in patients with Gastroesophageal Reflux Disease (GERD)
\nPrincipal Investigator:<\/strong> Nicholas Shaheen, MD MPH
\nSponsor:<\/strong> Ironwood Pharmaceuticals, Inc.<\/p>\n

Visit clinicaltrials.gov to learn more about this GERD Study<\/a><\/p>\n

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Phase 2, Multicenter, Open-Label, Extension Study to Evaluate the Safety and Tolerability of AK002 in Patients with Eosinophilic Gastritis and\/or Eosinophilic Gastroenteritis (AK002-003X\/ENIGMA)<\/strong><\/p>\n

Currently enrolling by invitation only<\/p>\n

Purpose:<\/strong> To evaluate the efficacy (eosinophil count) of AK002 in patients with Eosinophilic Gastritis (EG) and\/or Eosinophilic Gastroenteritis (EGE)
\nPrincipal Investigator:<\/strong> Evan Dellon, MD MPH
\nSponsor:<\/strong> Allakos, Inc.<\/p>\n

Visit clinicaltrials.gov to learn more about this ENIGMA Extension Study<\/a><\/p>\n

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Enrollment Closed<\/h1>\n\n\n\n\n\n\n
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A Phase 2, Multicenter Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamic Effect of AK002 in Patients with Eosinophilic Gastritis with or without Eosinophilic Gastroenteritis (AK002-003)<\/h2>\n

Enrollment Closed
\nPurpose:<\/strong> To evaluate the efficacy (histological response) of AK002 in adults with Eosinophilic Gastritis (EG) with ir without Eosinophilic Gastroenteritis (EGE)
\nPrincipal Investigator:<\/strong> Evan Dellon, MD MPH
\nSponsor:<\/strong> Allakos<\/p>\n

Visit clinicaltrials.gov to learn more about the ENIGMA Study<\/a><\/p>\n

\"Clinicaltrials.gov\"<\/a><\/td>\n<\/tr>\n

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\u00a0A Multicenter, Randomized, Double-Blind, Sham-Controlled Clinical Investigation of the EndoStim\u00ae Lower Esophageal Sphincter (LES) Stimulation System for the Treatment of Gastroesophageal Reflux Disease (GERD), Protocol # CS-100<\/h2>\n

Enrollment Closed
\nPurpose:<\/strong> To demonstrate the safety and effectiveness of the EndoStim\u00ae Lower Esophageal Sphincter (LES) Stimulation System in the treatment of subjects with gastroesophageal reflux disease (GERD)
\nPrincipal Investigator:<\/strong> Dr. Nicholas J. Shaheen, MD, MPH
\nSponsor:<\/strong> EndoStim<\/p>\n

Visit clinicaltrials.gov to learn more about the EndoStim Study<\/a><\/p>\n

\"Clinicaltrials.gov\"<\/a><\/td>\n<\/tr>\n

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Please contact us for more information regarding any of the above active CEDAS research studies:<\/p>\n