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We study how survival and death by apoptosis is regulated in cells.  We focus on these pathways in neurons during development, long-term maintenance, and disease.  We use molecular and cell biological approaches in multiple models including primary neurons, stem cells undergoing neuronal differentiation, and mouse models of neurodevelopmental disorders (e.g. Autism, Schizophrenia) and neurodegenerative (e.g. Alzheimer’s) disease.

Mohanish Deshmukh