For Graduate Students:
PHYI 702 - Experimental Physiology of Human Health & Disease (4.0)
Students learn the principles of cell, organ and systems physiology and pathophysiology required to identify important areas of current biomedical research. Companion course to PHYI 703 (offered in the spring semester). Both courses cover different physiological systems (cardiovascular, neuro, respiratory, etc) with emphasis on examples of specific diseases (channelopathies, schizophrenia, hypertension, diabetes, etc) and current research opportunities. PHYI 702 focuses on non-human model systems (cultured cells, mice, zebrafish, etc), while PHYI 703 focuses on approaches that utilize human samples or human genomics. Both courses emphasize the current research literature and include weekly journal-club discussion of assigned papers. Fall. Goy, Caron, Lund, Otey, Randell, Tzima, Zylka. MWF 9:00-10:20AM in 5201 MBRB.
PHYI 703 - Experimental Physiology of Human Health & Disease (4.0)
See description above. Spring. Goy, Arendshorst, Frohlich, Lund, Randell, Rawls. MWF 9:00-10:20AM in 5201 MBRB.
PHYI 705 - Communicating Scientific Results (1.0)
This course is required for students in the Physiology Program in years 2 and 3, and is only open to students in the PHYI and NBIO curricula. The goals of this class are:
- To develop in each student the ability to speak and write effectively about science—with ease, clarity and even pleasure!
- To develop the skill of illustrating talks effectively
- To eliminate the defensiveness provoked in students by being critiqued, edited, and rehearsed
- To build self-confidence in speaking and teaching
- To demystify various professional duties and give students practice in how they are executed
These goals are accomplished through multiple mechanisms: student presentations of PowerPoint and chalk talks, formal rehearsal with class buddies and formal presentations to the faculty, videotaping of the presentations and one-on-one review of the video with Dr. Stuart, critiques by Dr. Stuart and other students of presentations and writing assignments, critiquing of departmental seminars, training in audience engagement from a person experienced in theater. Each week a different faculty member from the C&M Physiology Department or the Neurobiology Curriculum visits the class to bring a fresh perspective. A lunch with these “visiting” faculty ends the semester. Fall. Goy. Fridays 1:00-2:30PM in 3118 Neuroscience Research Building.
PHYI 706 - Communicating Scientific Results (1.0)
See PHYI 705 above. Spring. Goy. Fridays 1:00-2:30PM in 3118 Neuroscience Research Building.
PHYI 751/752 - Seminar in Physiology (1.0)
Prerequisite, permission of the director of graduate studies. Weekly seminars emphasize current literature. Open only to Physiology program students. Staff.
PHYI/NBIO 722A - Cellular and Molecular Neurobiology: INTRODUCTORY MATERIAL & DEVELOPMENTAL NEUROBIOLOGY (10 sessions) (2.0)
Detailed course description Prerequisite, permission of course director. This introductory block covers basic molecular biology, as applied to neurons, and an overview of developmental neurobiology. Fall. Stuart and faculty.
PHYI/NBIO 722B - Cellular and Molecular Neurobiology: NEUROTRANSMITTER RECEPTORS (11 sessions) (2.0)
Prerequisite, permission of course director. This block considers membrane receptor molecules activated by neurotransmitters in the nervous system, with emphasis on ligand binding behavior and molecular and functional properties of different classes of receptors. Fall. Stuart and faculty.
PHYI/NBIO 722C - Cellular and Molecular Neurobiology: Electrical Signaling (17 sessions) (2.0)
Prerequisite, permission of course director. This block considers the genesis of electrical impulses in the nervous system with an emphasis on membrane potentials, voltage-gated and mechanically-gated ion channels, and structural features of neurons that influence coding. Fall. Sealock.
PHYI/NBIO 723A - Cellular and Molecular Neurobiology: SYNAPTIC MECHANISMS AND INTRACELLULAR SIGNALING (22 sessions) (2.0)
Prerequisite, permission of the course director. This block explores synaptic transmission: the mechanisms regulating the release of neurotransmitters from nerve terminals, including quantal release, vesicle and terminal membrane proteins, neurotransmitter transporters, and synaptic plasticity; and the biochemical signal transduction events following activation of neurotransmitter receptors including G-protein coupling, desensitization, signaling specificity, downstream effectors, calcium signaling and tyrosine kinases. Spring. Stuart and faculty.
PHYI/NBIO 723B - Cellular and Molecular Neurobiology: CNS: ANATOMY AND FUNCTION OF SENSORY AND MOTOR SYSTEMS (19 sessions) (2.0)
Prerequisite, permission of the course director. This block introduces the sensory pathways of vision, audition, taste, olfaction, pain, and touch, as well as the motor pathways of the spinal cord, basal ganglia, cerebellum, and motor cortex. Mechanisms of sensory information processing and motor execution are discussed. The section includes sessions on human brain neuroanatomy and brain imaging. Spring. Stuart and faculty.
PHYI/NBIO 724 - Developmental Neurobiology (3.0)
Prerequisite, permission of the instructor. A survey of nervous system development emphasizing detailed analysis of selected research topics such as neuronal induction, neural crest development, neuronal differentiation, synapse formation, neurotrophic factors, glial development, and the effects of experience. Fall. Crews, Polleux and faculty.