{"id":10994,"date":"2020-08-24T12:30:55","date_gmt":"2020-08-24T16:30:55","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/?post_type=directory&#038;p=10994"},"modified":"2024-08-16T12:37:31","modified_gmt":"2024-08-16T16:37:31","slug":"brian-diekman-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/brian-diekman-phd\/","title":{"rendered":"Brian Diekman, PhD"},"content":{"rendered":"<p>Dr. Diekman has established a research laboratory that utilizes regenerative medicine technologies to develop novel therapeutic approaches for osteoarthritis. One goal of the lab is to use engineered cartilage tissue as a model system to understand the mechanisms by which aging contributes to cartilage dysfunction and to screen for drugs that prevent cartilage dysfunction. The lab also uses genome editing of stem cells to investigate the genetic risk factors for osteoarthritis. In addition to experiments with cultured cells, work with rodent models allows the lab to test the feasibility of interventions designed to increase the regenerative capacity of cartilage tissue after injury.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-10760\" src=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2020\/07\/ogetrained2.jpg\" alt=\"\" width=\"133\" height=\"133\" srcset=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2020\/07\/ogetrained2.jpg 434w, https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2020\/07\/ogetrained2-300x300.jpg 300w, https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2020\/07\/ogetrained2-150x150.jpg 150w\" sizes=\"auto, (max-width: 133px) 100vw, 133px\" \/>\u00a0 OGE Mentoring Workshop<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Diekman has established a research laboratory that utilizes regenerative medicine technologies to develop novel therapeutic approaches for osteoarthritis. One goal of the lab is to use engineered cartilage tissue as a model system to understand the mechanisms by which aging contributes to cartilage dysfunction and to screen for drugs that prevent cartilage dysfunction. The &hellip; <a href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/brian-diekman-phd\/\" aria-label=\"Read more about Brian Diekman, PhD\">Read more<\/a><\/p>\n","protected":false},"featured_media":10995,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-10994","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Brian Diekman, PhD - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/brian-diekman-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brian Diekman, PhD - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"Dr. Diekman has established a research laboratory that utilizes regenerative medicine technologies to develop novel therapeutic approaches for osteoarthritis. One goal of the lab is to use engineered cartilage tissue as a model system to understand the mechanisms by which aging contributes to cartilage dysfunction and to screen for drugs that prevent cartilage dysfunction. 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