{"id":11012,"date":"2020-08-26T10:52:50","date_gmt":"2020-08-26T14:52:50","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/?post_type=directory&#038;p=11012"},"modified":"2022-12-01T16:12:17","modified_gmt":"2022-12-01T21:12:17","slug":"ben-philpot-phd-2","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/ben-philpot-phd-2\/","title":{"rendered":"Ben Philpot, PhD"},"content":{"rendered":"<p>The Philpot lab seeks to understand the pathophysiology underlying monogenic neurodevelopmental disorders, and we use this information to develop small molecule and gene therapies to treat these disorders.\u00a0Our research focuses on early-stage development of treatments for Pitt-Hopkins, Dup15q, and Angelman syndromes.\u00a0 Our lab has made key therapeutic discoveries, including developing an approach to unsilence the epigenetically-repressed paternal <em>UBE3A<\/em> allele as a novel treatment strategy for Angelman syndrome.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Philpot lab seeks to understand the pathophysiology underlying monogenic neurodevelopmental disorders, and we use this information to develop small molecule and gene therapies to treat these disorders.\u00a0Our research focuses on early-stage development of treatments for Pitt-Hopkins, Dup15q, and Angelman syndromes.\u00a0 Our lab has made key therapeutic discoveries, including developing an approach to unsilence the &hellip; <a href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/ben-philpot-phd-2\/\" aria-label=\"Read more about Ben Philpot, PhD\">Read more<\/a><\/p>\n","protected":false},"featured_media":12647,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-11012","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ben Philpot, PhD - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/ben-philpot-phd-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ben Philpot, PhD - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"The Philpot lab seeks to understand the pathophysiology underlying monogenic neurodevelopmental disorders, and we use this information to develop small molecule and gene therapies to treat these disorders.\u00a0Our research focuses on early-stage development of treatments for Pitt-Hopkins, Dup15q, and Angelman syndromes.\u00a0 Our lab has made key therapeutic discoveries, including developing an approach to unsilence the &hellip; 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