{"id":11621,"date":"2021-02-22T15:52:07","date_gmt":"2021-02-22T20:52:07","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/?post_type=directory&#038;p=11621"},"modified":"2021-02-22T15:52:07","modified_gmt":"2021-02-22T20:52:07","slug":"zoe-mcelligott-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/","title":{"rendered":"Zoe McElligott, PhD"},"content":{"rendered":"<div class=\"directory-post-content\">\n<h2>Research Interests<\/h2>\n<ul>\n<li>Mechanisms that underlie various affective disorders including anxiety disorders, depression and substance abuse<\/li>\n<\/ul>\n<h2>Research Synopsis<\/h2>\n<p>Research in the McElligott lab focuses on the circuits and plasticity that underlie the development and manifestation of psychiatric illness, specifically disorders on the affective spectrum including: alcohol use disorders, drug abuse and anxiety disorders. The lab has expertise in studying neurotransmission from the level of signaling in individual cells through behavior utilizing a variety of techniques including: whole-cell electrophysiology,\u00a0<em>in vivo<\/em>\u00a0and\u00a0<em>ex vivo<\/em>\u00a0fast-scan cyclic voltammetry, circuit manipulations (optogenetics, chemogenetics, caspase ablation), and behavioral assays.<\/p>\n<p>There are several ongoing projects in the lab. One area we are focused on explores the role of neurons in the central nucleus of the amygdala (CeA) that express the neuropeptide neurotensin and the role these neurons play in alcohol related phenotypes. Additionally we are interested in exploring how norepinephrine modulates neurotransmission within the brain and how the norepinephrine system itself is modulated in models of substance abuse and post-traumatic stress. Beyond these studies, we are actively engaged in several other collaborative projects with other labs at UNC, as well as around the world.<\/p>\n<h2>Publications<\/h2>\n<p><strong><a class=\"external-link\" title=\"\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=mcelligott_z\" rel=\"noopener noreferrer\">\u00a0View complete list of publications in PubMed<\/a><\/strong><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Research Interests Mechanisms that underlie various affective disorders including anxiety disorders, depression and substance abuse Research Synopsis Research in the McElligott lab focuses on the circuits and plasticity that underlie the development and manifestation of psychiatric illness, specifically disorders on the affective spectrum including: alcohol use disorders, drug abuse and anxiety disorders. The lab has &hellip; <a href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/\" aria-label=\"Read more about Zoe McElligott, PhD\">Read more<\/a><\/p>\n","protected":false},"featured_media":11620,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-11621","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Zoe McElligott, PhD - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zoe McElligott, PhD - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"Research Interests Mechanisms that underlie various affective disorders including anxiety disorders, depression and substance abuse Research Synopsis Research in the McElligott lab focuses on the circuits and plasticity that underlie the development and manifestation of psychiatric illness, specifically disorders on the affective spectrum including: alcohol use disorders, drug abuse and anxiety disorders. The lab has &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2021\/02\/zoe-mcelligott.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"130\" \/>\n\t<meta property=\"og:image:height\" content=\"150\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/\",\"name\":\"Zoe McElligott, PhD - Department of Cell Biology and Physiology\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2021\/02\/zoe-mcelligott.jpeg\",\"datePublished\":\"2021-02-22T20:52:07+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2021\/02\/zoe-mcelligott.jpeg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2021\/02\/zoe-mcelligott.jpeg\",\"width\":130,\"height\":150,\"caption\":\"Zoe McElligott\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Zoe McElligott, PhD\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/\",\"name\":\"Department of Cell Biology and Physiology\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Zoe McElligott, PhD - Department of Cell Biology and Physiology","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/zoe-mcelligott-phd\/","og_locale":"en_US","og_type":"article","og_title":"Zoe McElligott, PhD - Department of Cell Biology and Physiology","og_description":"Research Interests Mechanisms that underlie various affective disorders including anxiety disorders, depression and substance abuse Research Synopsis Research in the McElligott lab focuses on the circuits and plasticity that underlie the development and manifestation of psychiatric illness, specifically disorders on the affective spectrum including: alcohol use disorders, drug abuse and anxiety disorders. 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