{"id":11716,"date":"2021-04-11T11:35:55","date_gmt":"2021-04-11T15:35:55","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/?post_type=directory&#038;p=11716"},"modified":"2021-04-12T09:42:28","modified_gmt":"2021-04-12T13:42:28","slug":"timothy-elston-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/timothy-elston-phd\/","title":{"rendered":"Timothy Elston, PhD"},"content":{"rendered":"<h2>Research Interests<\/h2>\n<ul>\n<li>Signal Transduction<\/li>\n<li>Noise in Gene Expression<\/li>\n<li>Airway Surface Volume Regulation<\/li>\n<li>Motor Proteins<\/li>\n<\/ul>\n<h2>Research Synopsis<\/h2>\n<p class=\"p1\">My lab integrates computational approaches, including mathematical modeling and quantitative image analysis, with experimental investigations to understand complex cellular behavior. Current projects in the lab focus on cell fate decisions, polarity establishment and gradient sensing. The primary model system we use to study these cellular functions is the yeast\u00a0<span class=\"s1\"><i>Saccharomyces cerevisiae<\/i><\/span>. Our investigations combine microfluidic technology with live-cell microscopy to observe cellular behavior in well-controlled environments. This experimental platform provides a powerful system for developing and validating predictive models of cellular function. My lab also is involved in multiple collaborative projects to investigate these fundamental cellular processes in physiological contexts and their dysregulation in human disease.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research Interests Signal Transduction Noise in Gene Expression Airway Surface Volume Regulation Motor Proteins Research Synopsis My lab integrates computational approaches, including mathematical modeling and quantitative image analysis, with experimental investigations to understand complex cellular behavior. Current projects in the lab focus on cell fate decisions, polarity establishment and gradient sensing. The primary model system &hellip; <a href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/timothy-elston-phd\/\" aria-label=\"Read more about Timothy Elston, PhD\">Read more<\/a><\/p>\n","protected":false},"featured_media":11715,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-11716","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Timothy Elston, PhD - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/timothy-elston-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Timothy Elston, PhD - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"Research Interests Signal Transduction Noise in Gene Expression Airway Surface Volume Regulation Motor Proteins Research Synopsis My lab integrates computational approaches, including mathematical modeling and quantitative image analysis, with experimental investigations to understand complex cellular behavior. Current projects in the lab focus on cell fate decisions, polarity establishment and gradient sensing. 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