{"id":12757,"date":"2023-02-27T11:18:25","date_gmt":"2023-02-27T16:18:25","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/?post_type=directory&#038;p=12757"},"modified":"2024-11-06T11:47:14","modified_gmt":"2024-11-06T16:47:14","slug":"whitney-edwards-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/whitney-edwards-phd\/","title":{"rendered":"Whitney Edwards, PhD"},"content":{"rendered":"<h3><strong>Research Description<\/strong><\/h3>\n<p>Congenital heart diseases (CHDs) are characterized by structural malformations that arise from perturbations in the molecular programs that regulate heart development. CHD is the most common birth defect, affecting approximately 1% of all live births. Despite the prevalence of CHDs, the underlying cause remains unknown in most cases. My lab&#8217;s overarching goal is to identify the cellular processes essential for cardiac development and determine how these processes are altered in CHDs. We use a multifaceted approach to investigate molecular mechanisms of cardiogenesis, including mammalian cell culture, genetic mouse models, biochemical\/molecular studies, and transcriptomics.\u00a0 In addition, the lab emphasizes a proteomics-based approach to investigate the contribution of 1) protein expression dynamics, 2) protein interactions, and 3) post-translation regulation to heart development.<\/p>\n<h3><\/h3>\n","protected":false},"excerpt":{"rendered":"<p>Research Description Congenital heart diseases (CHDs) are characterized by structural malformations that arise from perturbations in the molecular programs that regulate heart development. CHD is the most common birth defect, affecting approximately 1% of all live births. Despite the prevalence of CHDs, the underlying cause remains unknown in most cases. My lab&#8217;s overarching goal is &hellip; <a href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/whitney-edwards-phd\/\" aria-label=\"Read more about Whitney Edwards, PhD\">Read more<\/a><\/p>\n","protected":false},"featured_media":12758,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-12757","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Whitney Edwards, PhD - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/whitney-edwards-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Whitney Edwards, PhD - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"Research Description Congenital heart diseases (CHDs) are characterized by structural malformations that arise from perturbations in the molecular programs that regulate heart development. CHD is the most common birth defect, affecting approximately 1% of all live births. Despite the prevalence of CHDs, the underlying cause remains unknown in most cases. 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