{"id":4653,"date":"2017-03-17T18:24:41","date_gmt":"2017-03-17T22:24:41","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/alain-burette-phd\/"},"modified":"2024-11-06T11:38:46","modified_gmt":"2024-11-06T16:38:46","slug":"alain-burette-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/alain-burette-phd\/","title":{"rendered":"Alain Burette, PhD"},"content":{"rendered":"

<\/p>\n

Assistant Professor
\nUNC-Chapel Hill<\/p>\n

\n

Education and Training<\/h2>\n

Blaise Pascal University, PhD, 1997<\/p>\n

Areas of Interest<\/h2>\n

Synapses are specialized sites of contact between neurons in the brain that are vital for the interneuronal signaling required for the processing and integration of information. Synapses are not simply organelles filled with a mixture of individual proteins; for proper function, these molecules must be organized into biological machines ranging in scale from molecular complexes to large organelles. Like their man-made counterparts, biological machines are composed of individual components that function in a coordinated fashion to perform specific functions. Malfunction of a single structural element can result in disease. I have used well-established light and electron microscopy techniques, along with innovative tools such as quantitative immunogold, electron tomography, FIB-SEM and super-resolution microscopy, to explore the nanoanatomy of synapses. My recent work involves the study of the spatial organization of proteins implicated in neurological disorders, with a special focus on the neurobiology of Angelman syndrome (a devastating neurodevelopmental disorder).<\/p>\n

\"\"
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Assistant Professor UNC-Chapel Hill Education and Training Blaise Pascal University, PhD, 1997 Areas of Interest Synapses are specialized sites of contact between neurons in the brain that are vital for the interneuronal signaling required for the processing and integration of information. Synapses are not simply organelles filled with a mixture of individual proteins; for proper … Read more<\/a><\/p>\n","protected":false},"featured_media":4654,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-4653","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"\nAlain Burette, PhD - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/alain-burette-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Alain Burette, PhD - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"Assistant Professor UNC-Chapel Hill Education and Training Blaise Pascal University, PhD, 1997 Areas of Interest Synapses are specialized sites of contact between neurons in the brain that are vital for the interneuronal signaling required for the processing and integration of information. 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