{"id":4664,"date":"2016-06-10T18:11:00","date_gmt":"2016-06-10T22:11:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/"},"modified":"2024-11-06T11:55:49","modified_gmt":"2024-11-06T16:55:49","slug":"douglas-phanstiel","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/","title":{"rendered":"Douglas Phanstiel, PhD"},"content":{"rendered":"

<\/p>\n

Associate Professor
\nUNC-Chapel Hill<\/p>\n

\n

Education and Training<\/h3>\n

University of California, San Diego, BS
\nUniversity of Wisconsin, PhD
\nStanford University, Postdoc<\/p>\n

Areas of Interest<\/h3>\n
Rheumatoid arthritis is an autoimmune disorder that effects 1.3 million people nationwide and has no known cure. The onset and progression of rheumatoid arthritis involves the complex interplay of a variety of cell types including macrophages, osteoclasts, and dendritic cells. Many of these cell are derived from or can be derived from monocytic precursors. The focus of our research is to better understand the molecular mechanisms that drive the transition from monocytes to each of these disease-relevant cell types. We are particularly interested in the phenomena of dynamic DNA looping and kinase signaling and the role that they play in lineage specificity and cell fate decisions. By better understanding the mechanisms that give rise to these cells we can improve our understanding of rheumatoid arthritis and potentially identify novel therapeutic targets. However, the knowledge we gain regarding gene regulation and cell signaling with inform our understanding of a wide variety of biological processes and human diseases. We employ a variety of technologies including genomics, proteomics, genome editing, and bioinformatics to characterize and functionally test molecular events driving monocyte differentiation.<\/div>\n


\nAwards and Honors<\/span><\/h3>\n
2015: K99\/R00 Pathway to Independence<\/span><\/div>\n
2012: Damon Runyon Fellowship Award<\/div>\n
<\/div>\n
\"\"<\/a><\/div>\n
<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Associate Professor UNC-Chapel Hill Education and Training University of California, San Diego, BS University of Wisconsin, PhD Stanford University, Postdoc Areas of Interest Rheumatoid arthritis is an autoimmune disorder that effects 1.3 million people nationwide and has no known cure. The onset and progression of rheumatoid arthritis involves the complex interplay of a variety of … Read more<\/a><\/p>\n","protected":false},"featured_media":9771,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-4664","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"\nDouglas Phanstiel, PhD - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Douglas Phanstiel, PhD - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"Associate Professor UNC-Chapel Hill Education and Training University of California, San Diego, BS University of Wisconsin, PhD Stanford University, Postdoc Areas of Interest Rheumatoid arthritis is an autoimmune disorder that effects 1.3 million people nationwide and has no known cure. The onset and progression of rheumatoid arthritis involves the complex interplay of a variety of … Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Cell Biology and Physiology\" \/>\n<meta property=\"article:modified_time\" content=\"2024-11-06T16:55:49+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2019\/01\/9B7A0359-1-e1585859343949-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"2382\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/\",\"name\":\"Douglas Phanstiel, PhD - Department of Cell Biology and Physiology\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2019\/01\/9B7A0359-1-e1585859343949-scaled.jpg\",\"datePublished\":\"2016-06-10T22:11:00+00:00\",\"dateModified\":\"2024-11-06T16:55:49+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2019\/01\/9B7A0359-1-e1585859343949-scaled.jpg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2019\/01\/9B7A0359-1-e1585859343949-scaled.jpg\",\"width\":2560,\"height\":2382,\"caption\":\"Doug Phanstiel\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Douglas Phanstiel, PhD\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/\",\"name\":\"Department of Cell Biology and Physiology\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Douglas Phanstiel, PhD - Department of Cell Biology and Physiology","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/","og_locale":"en_US","og_type":"article","og_title":"Douglas Phanstiel, PhD - Department of Cell Biology and Physiology","og_description":"Associate Professor UNC-Chapel Hill Education and Training University of California, San Diego, BS University of Wisconsin, PhD Stanford University, Postdoc Areas of Interest Rheumatoid arthritis is an autoimmune disorder that effects 1.3 million people nationwide and has no known cure. The onset and progression of rheumatoid arthritis involves the complex interplay of a variety of … Read more","og_url":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/","og_site_name":"Department of Cell Biology and Physiology","article_modified_time":"2024-11-06T16:55:49+00:00","og_image":[{"width":2560,"height":2382,"url":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2019\/01\/9B7A0359-1-e1585859343949-scaled.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/","url":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/","name":"Douglas Phanstiel, PhD - Department of Cell Biology and Physiology","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#primaryimage"},"image":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2019\/01\/9B7A0359-1-e1585859343949-scaled.jpg","datePublished":"2016-06-10T22:11:00+00:00","dateModified":"2024-11-06T16:55:49+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#primaryimage","url":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2019\/01\/9B7A0359-1-e1585859343949-scaled.jpg","contentUrl":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2019\/01\/9B7A0359-1-e1585859343949-scaled.jpg","width":2560,"height":2382,"caption":"Doug Phanstiel"},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/douglas-phanstiel\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/cellbiophysio\/"},{"@type":"ListItem","position":2,"name":"Douglas Phanstiel, PhD"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#website","url":"https:\/\/www.med.unc.edu\/cellbiophysio\/","name":"Department of Cell Biology and Physiology","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/cellbiophysio\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_upd_display_name":["Douglas Phanstiel, PhD"],"_upd_reverse_display_name":["Phanstiel, Douglas"],"_upd_last_name":["Phanstiel"],"_upd_first_name":["Douglas"],"_upd_sortorder_override":[],"_upd_sortorder":["1"],"_upd_gallery_summary":["<p style=\"text-align: left\"><strong>Associate Professor\r\n<\/strong><strong>Office:<\/strong> \u00a04019A Thurston-Bowles\r\n<strong>Phone:<\/strong> \u00a0608-609-8377\r\n<a class=\"email-link\" title=\"\" href=\"mailto:douglas_phanstiel@med.unc.edu\" target=\"_self\">Email<\/a>\u00a0| <a class=\"external-link\" title=\"\" href=\"http:\/\/phanstiel-lab.med.unc.edu\" target=\"_self\">Webpage<\/a><\/p>"],"_upd_no_link":[],"_upd_degree1":["PhD"],"_upd_degree2":[],"_upd_email":[[{"email_text":"douglas_phanstiel@med.unc.edu"}]],"_upd_phone":[[{"phone_text":"608-609-8377","phone_type":"Office Phone"}]],"_upd_address":[[{"address":{"address-1":"4019A Thurston Bowles","address-2":"Campus Box 7280","campus-box":"","city":"Chapel Hill","state":"NC","zip":"27599-7280"}}]],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/directory\/4664","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/directory"}],"about":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/types\/directory"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/directory\/4664\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/media\/9771"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/media?parent=4664"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}