{"id":4760,"date":"2016-09-21T18:24:00","date_gmt":"2016-09-21T22:24:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/"},"modified":"2026-02-23T09:59:50","modified_gmt":"2026-02-23T14:59:50","slug":"flavio-frohlich-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/","title":{"rendered":"Flavio Frohlich, PhD"},"content":{"rendered":"<p><!-- title_affiliation --><\/p>\n<p>Professor<strong><br \/>\n<\/strong>Associate Vice Chair of Research<br \/>\nDepartment of Psychiatry<br \/>\nDirector, <a id=\"OWA7baa227b-6020-a0c6-12f9-70dfb6cfe95a\" class=\"OWAAutoLink\" title=\"https:\/\/www.carolinaneurostimulation.org\/\" href=\"https:\/\/www.carolinaneurostimulation.org\/\" data-outlook-id=\"b65ca3e8-98d2-4950-9d46-c8eced583347\">Carolina Center for Neurostimulation<\/a><br \/>\nUniversity of North Carolina at Chapel Hill<\/p>\n<h2><strong>About<\/strong><\/h2>\n<p>Flavio received a degree in electrical engineering at the Swiss Federal Institute of Technology in Zurich, an International Diploma in electrical engineering at the Imperial College in London, his PhD in computational neurobiology at UC San Diego, and his MA in clinical psychology at UNC &#8211; Chapel Hill. He completed a postdoctoral fellowship at Yale University where he made the breakthrough discovery that the electric fields generated by the brain represent an active neuronal communication mode. In 2011, Flavio moved to UNC to translate this discovery into novel therapeutic strategies for disorders of the brain.<\/p>\n<p>Flavio is currently a tenured professor in the Departments of Psychiatry and Cell Biology and Physiology, where he also serves as Associate Vice Chair for Research. In addition, he is a member of the UNC Neuroscience Center and holds adjunct appointments in Biomedical Engineering and Neurology. He is also an adjunct professor of neurology at the University of Bern in Switzerland.<\/p>\n<div>\n<p class=\"elementToProof\">Flavio&#8217;s goal is to revolutionize how we treat psychiatric illnesses. His vision is that understanding brain network activity will enable the development of novel diagnosis and treatment paradigms. Flavio is convinced that such rational design of neurotherapeutics will open the door for individualized, highly effective brain stimulation in psychiatry. His research in transcranial alternating current stimulation (tACS) for treatment-resistant depression has achieved response rates of up to 80% in clinical trials. Flavio is passionate about combining different methodological approaches to scientific problems and is a pioneer in the field of network neuroscience. His research integrates neurobiology, engineering, and medicine. The\u00a0<b><a id=\"OWAe83bdc1c-6791-2376-ba24-c25282c728d9\" class=\"OWAAutoLink\" title=\"http:\/\/frohlichlab.org\/\" href=\"http:\/\/frohlichlab.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" data-auth=\"NotApplicable\" data-linkindex=\"0\" data-outlook-id=\"32a027de-9816-42e8-bedd-326aec35e8db\">Frohlich Lab<\/a><\/b>\u00a0(1) performs computational modeling, (2) combines electrophysiology, imaging, brain stimulation, and behavioral assays in animal models, (3) records and modulates human brain activity, and (4) studies new treatments in randomized controlled clinical trials. Flavio is the director of the\u00a0<b><a id=\"OWA3b4a1443-41c1-9045-4b6d-364729f5724e\" class=\"OWAAutoLink\" title=\"https:\/\/www.carolinaneurostimulation.org\/\" href=\"https:\/\/www.carolinaneurostimulation.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" data-auth=\"NotApplicable\" data-linkindex=\"1\" data-outlook-id=\"92a6883f-2a28-4d5c-8636-8b612932a165\">Carolina Center for Neurostimulation<\/a><\/b>, which integrates brain stimulation research and clinical trials in depression and anxiety.<\/p>\n<p class=\"elementToProof\">Flavio has received funding for his research from the National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, the Brain Behavior Foundation, the Human Frontier Science Program, and the Foundation of Hope. Flavio is the author of the textbook\u00a0<i>Network Neuroscience<\/i>, frequently presents his work at invited meetings and seminars, and has been recognized by numerous awards, including the NIMH Award for Innovative New Scientists in Biobehavioral Research and a NARSAD Distinguished Investigator Award. Flavio is also the founder of Pulvinar Neuro LLC, a neurotechnology company that received FDA Breakthrough Device designation and was acquired, and co-founder of Qortical Clinical Partners, a specialized CRO focused on neurotechnology clinical trials.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Professor Associate Vice Chair of Research Department of Psychiatry Director, Carolina Center for Neurostimulation University of North Carolina at Chapel Hill About Flavio received a degree in electrical engineering at the Swiss Federal Institute of Technology in Zurich, an International Diploma in electrical engineering at the Imperial College in London, his PhD in computational neurobiology &hellip; <a href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/\" aria-label=\"Read more about Flavio Frohlich, PhD\">Read more<\/a><\/p>\n","protected":false},"featured_media":15911,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-4760","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Flavio Frohlich, PhD - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Flavio Frohlich, PhD - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"Professor Associate Vice Chair of Research Department of Psychiatry Director, Carolina Center for Neurostimulation University of North Carolina at Chapel Hill About Flavio received a degree in electrical engineering at the Swiss Federal Institute of Technology in Zurich, an International Diploma in electrical engineering at the Imperial College in London, his PhD in computational neurobiology &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Cell Biology and Physiology\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-23T14:59:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2016\/09\/Headshot_FlavioFrohlich-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1708\" \/>\n\t<meta property=\"og:image:height\" content=\"2560\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/\",\"name\":\"Flavio Frohlich, PhD - Department of Cell Biology and Physiology\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2016\/09\/Headshot_FlavioFrohlich-scaled.jpg\",\"datePublished\":\"2016-09-21T22:24:00+00:00\",\"dateModified\":\"2026-02-23T14:59:50+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2016\/09\/Headshot_FlavioFrohlich-scaled.jpg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2016\/09\/Headshot_FlavioFrohlich-scaled.jpg\",\"width\":1708,\"height\":2560,\"caption\":\"Flavio Frohlich poses for a portrait on April 30, 2025 at the Carolina Center for Neuroscience in Chapel Hill, NC. Frohlich recently received the Brain &amp; Behavior Research Foundation\u2019s Distinguished Investigator Grant. Frohlich will develop and test a novel non-invasive neurostimulation approach (aperiodic tACS) designed to rapidly reduce depression symptoms in women who are pregnant. tACS, or transcranial alternating current stimulation, has been shown to be safe and effective in major depressive disorder in several pilot trials. 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Frohlich recently received the Brain &amp; Behavior Research Foundation\u2019s Distinguished Investigator Grant. Frohlich will develop and test a novel non-invasive neurostimulation approach (aperiodic tACS) designed to rapidly reduce depression symptoms in women who are pregnant. tACS, or transcranial alternating current stimulation, has been shown to be safe and effective in major depressive disorder in several pilot trials. (Photograph by Jeyhoun Allebaugh\/UNC-Chapel Hill)."},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/flavio-frohlich-phd\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/cellbiophysio\/"},{"@type":"ListItem","position":2,"name":"Flavio Frohlich, PhD"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#website","url":"https:\/\/www.med.unc.edu\/cellbiophysio\/","name":"Department of Cell Biology and Physiology","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/cellbiophysio\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_upd_display_name":["Flavio Frohlich, PhD"],"_upd_reverse_display_name":["Frohlich, Flavio"],"_upd_last_name":["Frohlich"],"_upd_first_name":["Flavio"],"_upd_sortorder_override":[],"_upd_sortorder":["1"],"_upd_gallery_summary":["<p style=\"text-align: left\"><strong>Professor\r\n<\/strong><strong>Office:<\/strong> \u00a06018A MEJ\r\n<strong>Phone:<\/strong> \u00a0919-966-4584\r\n<a class=\"email-link\" title=\"\" href=\"mailto:flavio_frohlich@med.unc.edu\" target=\"_self\">Email<\/a> | <a class=\"external-link\" title=\"\" href=\"http:\/\/frohlichlab.org\/\" target=\"_self\">Webpage<\/a><\/p>"],"_upd_no_link":[],"_upd_degree1":["PhD"],"_upd_degree2":[],"_upd_email":[[{"email_text":"flavio_frohlich@med.unc.edu"}]],"_upd_phone":[[{"phone_text":"919-966-4584","phone_type":"Office Phone"}]],"_upd_address":[[{"address":{"address-1":"60108A Mary Ellen Jones","address-2":"Campus Box 7250","campus-box":"","city":"Chapel Hill","state":"NC","zip":"27599-7250"}}]],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/directory\/4760","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/directory"}],"about":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/types\/directory"}],"version-history":[{"count":4,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/directory\/4760\/revisions"}],"predecessor-version":[{"id":15914,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/directory\/4760\/revisions\/15914"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/media\/15911"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/media?parent=4760"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}