{"id":14763,"date":"2025-02-04T11:10:34","date_gmt":"2025-02-04T16:10:34","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/?p=14763"},"modified":"2025-02-25T12:19:50","modified_gmt":"2025-02-25T17:19:50","slug":"understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/","title":{"rendered":"Heather McCauley receives a Junior Faculty Development Award"},"content":{"rendered":"

The UNC Provost\u2019s Office awarded Heather McCauley a Junior Faculty Development Award to create a new humanized mouse model that more closely replicates complex epithelial and immune cell dynamics in the gut.\u00a0<\/em><\/p>\n

\n

Lining the intestines are rare hormone-producing cells called enteroendocrine cells that sense nutrients, gut microbes, and metabolites in the food we eat. These cells can even detect physical cues like how much our intestines stretch when we consume a meal. In response to these changes, enteroendocrine cells secrete a slew of hormonal peptides, metabolites, neurotransmitters, and cytokines throughout the body to prepare it for an influx of nutrients. But enteroendocrine cells may also play a central yet elusive role in gastrointestinal health.<\/p>\n

\"McCauley,
Heather McCauley received a UNC Provost Junior Faculty Development Award to develop a new humanized mouse model that more closely replicates in vivo gut physiology.<\/figcaption><\/figure>\n

Enteroendocrine cells are often dysregulated in many metabolic and gastrointestinal disorders but normalize with dietary changes. This leads many scientists to wonder if abnormalities in these cells are a contributing cause or consequence of gastrointestinal dysfunction. Heather McCauley, an assistant professor in the Department of Cell Biology and Physiology at the University of North Carolina at Chapel Hill recently received an R.J. Reynolds Junior Faculty Development Award from the Provost\u2019s Office to develop a powerful new humanized mouse model that more closely replicates intestinal physiology and function to help answer this question.<\/p>\n

McCauley hypothesizes that enteroendocrine cells play a causative role in metabolic and gastrointestinal diseases by serving as the mechanistic links between diet, dysbiosis, and gut inflammation. \u201cWe anticipate that targeting enteroendocrine cells through dietary interventions or pharmacology may be an underappreciated avenue for prevention or treatment of all metabolic and inflammatory diseases with dietary risk,\u201d said McCauley.<\/p>\n

\"An
Enteroendocrine cells (purple), nestled between epithelial cells in the gut, sense changes after a meal and serve as relay cells, sending key signals to underlying immune cells.<\/figcaption><\/figure>\n

It is well known that enteroendocrine cells regulate their epithelial cell neighbors in the gut. McCauley proposes that enteroendocrine signaling may also regulate neurons, fibroblasts, and immune cells underlying the intestinal epithelium that are too far away to detect nutrient intake. If enteroendocrine signaling becomes dysregulated, immune cells in these areas may not receive the key messages needed to maintain gut health, resulting in gut inflammation.<\/p>\n

The problem is that scientists have been unable to comprehensively replicate human immune cell dynamics in mouse models of gastrointestinal disease. Current research strategies are limited to in vitro<\/em> modeling using human pluripotential stem cell-derived organoids (HIOs), which do not fully capture the complex multi-cell signaling landscape of in vivo<\/em> gut physiology.<\/p>\n

To solve this problem, McCauley\u2019s team plans to develop a new mouse model with a humanized immune system. They will then engraft HIOs with and without enteroendocrine cells into the mice. \u201cThis Development Award will enable our lab to develop this humanized mouse model and subsequent transplantation of HIOs to determine the impact of enteroendocrine cells on immune cell development, recruitment, and function in response to [gut] cues,\u201d said McCauley.<\/p>\n

\n

Written by Tiffany Garbutt, PhD<\/em><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

The UNC Provost\u2019s Office awarded Heather McCauley a Junior Faculty Development Award to create a new humanized mouse model that more closely replicates complex epithelial and immune cell dynamics in the gut.\u00a0 Lining the intestines are rare hormone-producing cells called enteroendocrine cells that sense nutrients, gut microbes, and metabolites in the food we eat. These … Read more<\/a><\/p>\n","protected":false},"author":77299,"featured_media":14764,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[52,2],"tags":[93,115,117,113,114,116],"featured-item":[],"class_list":["post-14763","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-featured-news","category-news","tag-cell-signaling","tag-dysbiosis","tag-gastrointestinal-disorders","tag-gastrointestinal-health","tag-immunology","tag-inflammation","odd"],"acf":[],"yoast_head":"\nHeather McCauley receives a Junior Faculty Development Award - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Understanding the role of gut messenger cells in gastrointestinal disease\" \/>\n<meta property=\"og:description\" content=\"Health McCauley received a Junior Faculty Development Award to create a new humanized mouse model that more closely replicates complex immune cell dynamics in the gut.\u00a0\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Cell Biology and Physiology\" \/>\n<meta property=\"article:published_time\" content=\"2025-02-04T16:10:34+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-25T17:19:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1812\" \/>\n\t<meta property=\"og:image:height\" content=\"1262\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Tiffany Garbutt\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Understanding the role of gut messenger cells in gastrointestinal disease\" \/>\n<meta name=\"twitter:description\" content=\"Health McCauley received a Junior Faculty Development Award to create a new humanized mouse model that more closely replicates complex immune cell dynamics in the gut.\u00a0\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Tiffany Garbutt\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/\"},\"author\":{\"name\":\"Tiffany Garbutt\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/9230fee8743ee29e077109c0143e75e0\"},\"headline\":\"Heather McCauley receives a Junior Faculty Development Award\",\"datePublished\":\"2025-02-04T16:10:34+00:00\",\"dateModified\":\"2025-02-25T17:19:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/\"},\"wordCount\":543,\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg\",\"keywords\":[\"cell signaling\",\"dysbiosis\",\"gastrointestinal disorders\",\"gastrointestinal health\",\"immunology\",\"inflammation\"],\"articleSection\":[\"Featured News\",\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/\",\"name\":\"Heather McCauley receives a Junior Faculty Development Award - Department of Cell Biology and Physiology\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg\",\"datePublished\":\"2025-02-04T16:10:34+00:00\",\"dateModified\":\"2025-02-25T17:19:50+00:00\",\"author\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/9230fee8743ee29e077109c0143e75e0\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg\",\"width\":1812,\"height\":1262,\"caption\":\"Enteroendocrine cells (purple), nestled between epithelial cells in the gut, sense changes after a meal and serve as relay cells, sending key signals to underlying immune cells.\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Heather McCauley receives a Junior Faculty Development Award\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/\",\"name\":\"Department of Cell Biology and Physiology\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/9230fee8743ee29e077109c0143e75e0\",\"name\":\"Tiffany Garbutt\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ef5a3f4b8d55785f2fefd2aacd67997f72c357d880f4b2e682e492ab034bff00?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ef5a3f4b8d55785f2fefd2aacd67997f72c357d880f4b2e682e492ab034bff00?s=96&d=mm&r=g\",\"caption\":\"Tiffany Garbutt\"},\"description\":\"UNC McAllister Heart Institute\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/author\/tgarbutt\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Heather McCauley receives a Junior Faculty Development Award - Department of Cell Biology and Physiology","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/","og_locale":"en_US","og_type":"article","og_title":"Understanding the role of gut messenger cells in gastrointestinal disease","og_description":"Health McCauley received a Junior Faculty Development Award to create a new humanized mouse model that more closely replicates complex immune cell dynamics in the gut.\u00a0","og_url":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/","og_site_name":"Department of Cell Biology and Physiology","article_published_time":"2025-02-04T16:10:34+00:00","article_modified_time":"2025-02-25T17:19:50+00:00","og_image":[{"width":1812,"height":1262,"url":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg","type":"image\/jpeg"}],"author":"Tiffany Garbutt","twitter_card":"summary_large_image","twitter_title":"Understanding the role of gut messenger cells in gastrointestinal disease","twitter_description":"Health McCauley received a Junior Faculty Development Award to create a new humanized mouse model that more closely replicates complex immune cell dynamics in the gut.\u00a0","twitter_image":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg","twitter_misc":{"Written by":"Tiffany Garbutt","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#article","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/"},"author":{"name":"Tiffany Garbutt","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/9230fee8743ee29e077109c0143e75e0"},"headline":"Heather McCauley receives a Junior Faculty Development Award","datePublished":"2025-02-04T16:10:34+00:00","dateModified":"2025-02-25T17:19:50+00:00","mainEntityOfPage":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/"},"wordCount":543,"image":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg","keywords":["cell signaling","dysbiosis","gastrointestinal disorders","gastrointestinal health","immunology","inflammation"],"articleSection":["Featured News","News"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/","url":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/","name":"Heather McCauley receives a Junior Faculty Development Award - Department of Cell Biology and Physiology","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#primaryimage"},"image":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg","datePublished":"2025-02-04T16:10:34+00:00","dateModified":"2025-02-25T17:19:50+00:00","author":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/9230fee8743ee29e077109c0143e75e0"},"breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#primaryimage","url":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg","contentUrl":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg","width":1812,"height":1262,"caption":"Enteroendocrine cells (purple), nestled between epithelial cells in the gut, sense changes after a meal and serve as relay cells, sending key signals to underlying immune cells."},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/understanding-the-role-of-gut-messenger-cells-in-gastrointestinal-disease\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/cellbiophysio\/"},{"@type":"ListItem","position":2,"name":"Heather McCauley receives a Junior Faculty Development Award"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#website","url":"https:\/\/www.med.unc.edu\/cellbiophysio\/","name":"Department of Cell Biology and Physiology","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/cellbiophysio\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/9230fee8743ee29e077109c0143e75e0","name":"Tiffany Garbutt","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/ef5a3f4b8d55785f2fefd2aacd67997f72c357d880f4b2e682e492ab034bff00?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ef5a3f4b8d55785f2fefd2aacd67997f72c357d880f4b2e682e492ab034bff00?s=96&d=mm&r=g","caption":"Tiffany Garbutt"},"description":"UNC McAllister Heart Institute","url":"https:\/\/www.med.unc.edu\/cellbiophysio\/author\/tgarbutt\/"}]}},"featured_image":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407-300x209.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407-768x535.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407-1024x713.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2025\/02\/Enteroendocrine-cells-in-gut-e1738616684407-150x150.jpg","featured_image_alt":"An illustration of enteroendocrine cells in the gut","category_details":[{"name":"Featured News","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/category\/featured-news\/"},{"name":"News","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/category\/news\/"}],"tag_details":[{"name":"cell signaling","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/tag\/cell-signaling\/"},{"name":"dysbiosis","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/tag\/dysbiosis\/"},{"name":"gastrointestinal disorders","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/tag\/gastrointestinal-disorders\/"},{"name":"gastrointestinal health","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/tag\/gastrointestinal-health\/"},{"name":"immunology","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/tag\/immunology\/"},{"name":"inflammation","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/tag\/inflammation\/"}],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/posts\/14763","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/users\/77299"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/comments?post=14763"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/posts\/14763\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/media\/14764"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/media?parent=14763"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/categories?post=14763"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/tags?post=14763"},{"taxonomy":"featured-item","embeddable":true,"href":"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-json\/wp\/v2\/featured-item?post=14763"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}