{"id":4134,"date":"2011-02-25T19:00:00","date_gmt":"2011-02-26T00:00:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/"},"modified":"2018-10-17T13:41:11","modified_gmt":"2018-10-17T17:41:11","slug":"philpot-lab-publication","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/","title":{"rendered":"Philpot lab publication sheds light on function of NMDA receptors"},"content":{"rendered":"<div>\n<p>\u00a0<\/p>\n<div class=\"image-section\">\n<figure class=\"thumbnail wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-4135\" src=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2018\/06\/philpot-lab-publication-image2-228x300.jpeg\" alt=\"image2\" width=\"300\" height=\"200\"><figcaption class=\"caption wp-caption-text\">Nature Neuroscience, volume 14, number 3 March 2011<\/figcaption><\/figure>\n<\/div>\n<div>\n<p><i>March 2011 \u2013<\/i> Researchers in Dr. Ben Philpot\u2019s lab have discovered a new role for a class of receptors that underlie learning and memory in the brain. In a study published in the journal <i><a class=\"external-link\" href=\"http:\/\/www.nature.com\/neuro\/index.html\">Nature Neuroscience<\/a><\/i>, they found that one type of these receptors \u2013 the NR3A subtype of NMDA receptors \u2013 is expressed at high levels during formative periods of early brain development, where it promotes the release of brain neurotransmitters and weakens connections between neurons. Since NMDA receptors contribute to a large number of neurological disorders \u2013 including schizophrenia, neuropathic pain, Alzheimer\u2019s disease, forms of mental retardation, and ischemic injury \u2013 the researchers\u2019 findings are of particular importance because they suggest a novel functions for these receptors in the human brain. This work was also highlighted in the <i>Nature Neuroscience<\/i>\u2018s <a class=\"external-link\" href=\"http:\/\/www.nature.com\/neuro\/journal\/v14\/n3\/full\/nn0311-274.html\">News &amp; View section<\/a>.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 Nature Neuroscience, volume 14, number 3 March 2011 March 2011 \u2013 Researchers in Dr. Ben Philpot\u2019s lab have discovered a new role for a class of receptors that underlie learning and memory in the brain. In a study published in the journal Nature Neuroscience, they found that one type of these receptors \u2013 the &hellip; <a href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/\" aria-label=\"Read more about Philpot lab publication sheds light on function of NMDA receptors\">Read more<\/a><\/p>\n","protected":false},"author":80868,"featured_media":4135,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[5,17],"featured-item":[],"class_list":["post-4134","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-philpot-news","tag-publications-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Philpot lab publication sheds light on function of NMDA receptors - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Philpot lab publication sheds light on function of NMDA receptors - Department of Cell Biology and Physiology\" \/>\n<meta property=\"og:description\" content=\"\u00a0 Nature Neuroscience, volume 14, number 3 March 2011 March 2011 \u2013 Researchers in Dr. Ben Philpot\u2019s lab have discovered a new role for a class of receptors that underlie learning and memory in the brain. In a study published in the journal Nature Neuroscience, they found that one type of these receptors \u2013 the &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Cell Biology and Physiology\" \/>\n<meta property=\"article:published_time\" content=\"2011-02-26T00:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-10-17T17:41:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2018\/06\/philpot-lab-publication-image2.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"440\" \/>\n\t<meta property=\"og:image:height\" content=\"580\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Nathaniel Bailey\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Nathaniel Bailey\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/\"},\"author\":{\"name\":\"Nathaniel Bailey\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/#\/schema\/person\/5858263096b03dd1d401a4f6e847b994\"},\"headline\":\"Philpot lab publication sheds light on function of NMDA receptors\",\"datePublished\":\"2011-02-26T00:00:00+00:00\",\"dateModified\":\"2018-10-17T17:41:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/\"},\"wordCount\":149,\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/wp-content\/uploads\/sites\/734\/2018\/06\/philpot-lab-publication-image2.jpeg\",\"keywords\":[\"Philpot news\",\"Publications news\"],\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/\",\"url\":\"https:\/\/www.med.unc.edu\/cellbiophysio\/philpot-lab-publication\/\",\"name\":\"Philpot lab publication sheds light on function of NMDA receptors - 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