{"id":4144,"date":"2011-12-21T18:20:00","date_gmt":"2011-12-21T23:20:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/potential-treatment-strategy-for-angelman-syndrome-identified\/"},"modified":"2018-10-17T13:41:25","modified_gmt":"2018-10-17T17:41:25","slug":"potential-treatment-strategy-for-angelman-syndrome-identified","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/potential-treatment-strategy-for-angelman-syndrome-identified\/","title":{"rendered":"Potential treatment strategy for Angelman syndrome identified by Philpot, Zylka and Roth"},"content":{"rendered":"
\n

December 2011 \u2013 Collaborators Ben Philpot, Mark Zylka and Bryan Roth identify compounds that cause the dormant Ube3a gene to be expressed.<\/p>\n

\n
\"image2\"
At top, a mouse brain showing flourescent expression of the UBE3A gene, and below, lack of expression when the maternal copy of the gene is missing.<\/figcaption><\/figure>\n<\/div>\n
\n

December 2011 <\/i>\u2013 An interdisciplinary team of UNC scientists say they have found a way to \u201cawaken\u201d the paternal allele of Ube3a, which could lead to a potential treatment strategy for Angelman syndrome (AS). Their results were published online by the journal Nature. Read the complete UNC School of Medicine news release >><\/a><\/p>\n

Simons Foundation Autism Research Institute news release >> <\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

<\/p>\n

December 2011 – Collaborators Ben Philpot, Mark Zylka and Bryan Roth identify compounds that cause the dormant Ube3a gene to be expressed.<\/p>\n","protected":false},"author":80868,"featured_media":4145,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[5,29],"featured-item":[],"class_list":["post-4144","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-philpot-news","tag-zylka-news","odd"],"acf":[],"yoast_head":"\nPotential treatment strategy for Angelman syndrome identified by Philpot, Zylka and Roth - Department of Cell Biology and Physiology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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